People Hanka Venselaar Structural bioinformatics

Structural bioinformatics validating, improving and interpretating protein structures

This research group uses the information obtained from 3D-protein structures and homology models to answer (bio) medical questions. To do so, they work on the validation, improvement, and interpretation of protein structures.

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Structural bioinformatics validating, improving and interpretating protein structures

The 3D-conformation of proteins hold a wealth of information that can be beneficial for (bio)medical research. In our group, we work on the analysis and interpretation of these proteins structures. We study the structures of proteins in order to understand their function and the effect of mutations. Where necessary we can build homology models for non-existing structures and use other predictive techniques. We work closely in collaboration with (bio)medical researchers in order to understand the molecular basics of life. 

Research group leader

Hanka Venselaar PhD

+31 (0)24 361 63 74
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Aims of this research group

  • to understand molecular mechanisms of health and disease
  • to collect and combine structural data to predict new information
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Aims of this research group

This research group aims:
  • to understand molecular mechanisms of health and disease;
  • to collect and combine structural data to predict new information;
  • to use this knowledge/data in collaborative projects;
  • to teach Structural Bioinformatics to students in the fields of Molecular and Biomedical Sciences.

Discoveries of this research group

  • Automatic Mutation server HOPE
  • Tolerance plots based on homologous domains 
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Useful links CMBI film

Team

Radboudumc Technology Center Bioinformatics

The Bioinformatics technology center aims to raise and solve biological questions using the most recent computer technologies and big data solutions.

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Radboud Institute for Molecular Life Sciences

Our main aim is to achieve a greater understanding of the molecular mechanisms of disease. By integrating fundamental and clinical research, we obtain multifaceted knowledge of (patho)physiological processes. read more