News items related to the Radboud Institute for Molecular Life Sciences.
4,8 million euros for prevention of tuberculosis among people with diabetes in Africa16 July 2019
Reinout van Crevel and Lindsey te Brake have received European funding of 4.8 million euros to lead an international consortium to screen thousands of people with diabetes in Uganda and Tanzania for TB, and investigate the effect and costs of 3 months preventive treatment for TB.
Summer greetings from René Bindels5 July 2019
In this last newsletter before the summer break and before I wish you all a happy holiday, I would like to briefly summarize the first half of 2019 and especially look ahead to the interesting activities that will take place in the second half of the year.
Prostate cancer theranostics imaging, surgical guidance, and targeted photodynamic therapy5 July 2019
In Theranostics, Mark Rijpkema and colleagues present the development of a novel multimodal tracer that targets both preoperative imaging, surgical guidance, and targeted photodynamic therapy of PSMA-expressing prostate cancer.
Effects of prophylactic haloperidol on long-term quality of life in ICU Patients4 July 2019
In Anesthesiology, Paul Rood, Marieke Zegers and Mark van den Boogaard described that prophylactic haloperidol use does not affect long-term quality of life in critically ill patients at high risk for delirium.
Awarded KWF grants for Radboudumc researchers2 July 2019
The Dutch Cancer Society (KWF) has awarded 25.5 million euros to 50 new research projects in 16 different institutes. 8 grants are awarded to Radboudumc researchers. We congratulate our researchers with this funding and wish them success with their great work.
Jan Smit appointed as dean / vice chair27 June 2019
Professor Jan Smit, current head of the Department of Internal Medicine, will be appointed as dean and vice chair of the Radboud university medical center as of 1 August. Within the Executive Board, Jan Smit will be particularly tasked with the portfolio of education and research.
Midsummer night event very successful25 June 2019
Almost 300 PhD candidates and postdocs from DCMN, RIHS and RIMLS enjoyed an inspiring and tasty Midsummer Night Event. Dean a.i. Jan Smit opened the event, after which Louise Lagendijk presented about 'selfcare is healthcare and positive psychology’.
New opportunity for Henk Stunnenberg24 June 2019
After more than 22 years, Henk Stunnenberg, theme Cancer development and immune defense, has left the Radboud University, Dept. of Molecular Biology, to take up a position at the Prinses Maxima Centre for pediatric oncology in Utrecht. On Friday 5 July a farewell drink is being organized.
Radboudumc Master Prize for Mark van Goor18 June 2019
Mark van Goor, theme Renal disorders, received the Radboudumc Master Prize for his MSc thesis entitled “High-resolution structure of the renal calcium channel TRPV5 revealed with cryo-EM”, which was based on his internship at the lab of Prof. Yifan Cheng, USA.
Exome sequencing in routine diagnostics: a generic test for 254 patients with primary immunodeficiencies18 June 2019
Exome sequencing may provide a genetic diagnosis in a significant number of patients in a single genetic test. Alexander Hoischen and Mihai Netea, theme Infectious diseases and global health, and colleagues, published their results in Genome Medicine.
Lowering cholesterol is not enough to reduce hyperactivity of the immune system14 June 2019
In Cell Metabolism, Siroon Bekkering, theme Vascular damage, and colleagues, provide a novel potential explanation for the residual cardiovascular risk, related to persistent activation of the immune system in patients with hypercholesterolemia who are treated with statins.
A personal touch of Johan van der Vlag13 June 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Johan van der Vlag.
Peter van der Kraan new theme leader Inflammatory diseases13 June 2019
It is our pleasure to introduce Peter van der Kraan from the Dept. of Rheumatology, as the new leader of our theme Inflammatory diseases. As such he will be the successor of Irma Joosten who has done an outstanding job in the last years as theme leader, for which we thank her wholeheartedly.
Studying the function of liver cancer genes in mini-organs24 May 2019
Michiel Vermeulen, theme Cancer development and immune defense, and colleagues, have developed a human model in which they use organoids, or mini organs, to study the function of specific genes that are mutated in liver cancer. Their results were published in the scientific journal Cell Stem Cell.
Three VIDI grants for RIMLS researchers24 May 2019
Matthijs Jore, Daniele Tauriello and Johannes Textor are each to receive up to 800,000 euros to develop an innovative research theme and to build up their own research group. NWO is awarding the Vidi grant as part of the Innovational Research Incentives Scheme.
Graduate school news Adjusted PhD guidelines23 May 2019
It should be emphasized that the quality, and not the number of chapters, determines the assessment by the manuscript committee. To avoid the wrong emphasis on quantity, it is not recommended to have more than three publishable chapters in the thesis.
Universal tumor BRCA1/2 testing of ovarian cancer13 May 2019
Marjolijn Ligtenberg, Janet Vos and Nicoline Hoogerbrugge, assessed the feasibility of a workflow for universal tumor DNA BRCA1/2 testing of all newly diagnosed OC patients as prescreen for PARPi treatment and cancer predisposition testing. They have published their findings in the JNCI.
A cozy relationship; the enhancer landscape of embryonic stem cells13 May 2019
In Nature Cell Biology, Yaser Atlasi, Wout Megchelenbrink and colleagues from the group of Henk Stunnenberg, theme Cancer development and immune defense, published a combination of experimental and bioinformatic approaches to study enhancer regulation in different states of embryonic stem cells.
Special microscope films how gateway in kidney cells opens and closes6 May 2019
One of the gateways in the kidney cell virtually exclusively allows calcium through. But how does that calcium channel work exactly? What does the molecular machine look like that makes sure that the channel opens and closes?