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Radboudumc to lead research team into tackling future pandemics NWO funds complexity research on pandemics

5 August 2021

The Radboudumc is going to lead a study on how to deal with future pandemics, together with Radboud University and the University of Amsterdam. Rick Quax from the Informatics Institute/IAS is involved in this project.

Research into treatment for bladder pain syndrome will now be reimbursed

4 August 2021

Bladder pain syndrome, also called interstitial cystitis, is a chronic benign condition of the urinary bladder

More variants TLR7 gene found in young healthy men with severe Covid-19 Screening and accelerated vaccination for TLR7 immunodeficiency

3 August 2021

Spanish-Dutch research has revealed two new mutations in the TLR7 gene in healthy young men who became seriously ill with severe Covid-19.

Senior Kolff Fellowship for Jeroen de Baaij

29 July 2021

Jeroen de Baaij, theme Renal disorders, received a prestigious Senior Kolff grant from The Dutch Kidney Foundation. His project aims to establish dietary approaches against vascular calcification in chronic kidney disease.

Differences in the number of de novo mutations between individuals due to small family-specific effects and stochasticity

28 July 2021

Christian Gilissen and colleagues investigated whether there is a family-specific contribution to the number of de novo mutations in the DNA of offspring and published the results in the Genome Research.

Christa Sperna Weiland, Erwin van Geenen and Joost Drenth discuss the best strategy to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis

28 July 2021

Christa Sperna Weiland, Erwin van Geenen and Joost Drenth, published in Lancet Gastroenterology & Hepatology a systematic review and network meta-analysis to determine the most efficacious prophylaxis strategy to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis.

ZonMw Gender in Research competition awarded to Genderful Research World Consortium

27 July 2021

Natalia Valdrighi and Esmeralda Blaney Davidson won the competition to create a plan for the dissemination of the knowledge and skills gained during the Gender in Research workshop amongst their peers, colleagues and institution, financed by ZonMw and CIHR-IGH in Canada.

Young people with colorectal cancer deserve their own treatment

27 July 2021

Richarda de Voer and Marjolijn Ligtenberg's study on clinical, pathological, genetic and molecular characteristics of colorectal tumors in adolescents and adults 25 years of age or younger is published in Clinical Gastroenterology and Hepatology.

Nijmegen literally puts Digital Health on the map Flourishing ecosystem gets its own interactive overview

22 July 2021

Digital Health is thriving in the Nijmegen region, where it contributes to better care and health and also creates jobs. To bring developers and end users even closer together, The Economic Board and the Radboudumc are introducing the Interactive Digital Health map.

Jeroen de Baaij Appointed associate professor

21 July 2021

Jeroen de Baaij, from the department of Physiology, has been appointed associate professor Kidney Physiology as of 1 August 2021.

Michiel Vermeulen and Klaas Mulder receive funding from ZonMw for a collaborative project using stem cell-based models

15 July 2021

Michiel Vermeulen and Klaas Mulder, theme Cancer development and immune defense, receive funding from ZonMw for a collaborative project to develop a stem cell based model to study early human embryogenesis.

ZonMw funding for PSIDER program

14 July 2021

Michiel Vermeulen, Klaas Mulder and Nael Nadif Kasri receive funding from ZonMw for a collaborative project to develop a stem cell based model to study early human embryogenesis.

Happy summer greetings from René Bindels

14 July 2021

Before most colleagues enjoy their well-deserved summer break, I would like to briefly share these wishes with you...

VIDI grants for researchers of Radboud university medical center

14 July 2021

Several Radboudumc researchers have been awarded a VIDI grant by the Dutch Organisation for Scientific Research (NWO). They each receive a sum of 800,000 euros, which they will use over the next five years to develop their own innovative line of research and to set up a research group.

Sonlicromanol seems promising for certain cancers Khondrion announces publication in PLOS ONE of new research

13 July 2021

Khondrion announces publication in PLOS ONE of new research showing normalisation of prostate cancer stem cell mPGES-1 overexpression and inhibition of cancer spheroid growth by sonlicromanol’s active metabolite.

Newborn screening in sight through the discovery of novel disease biomarkers by new technique

8 July 2021

To identify new biomarkers that can be used in the newborn screening protocol, also known as the neonatal heel prick, Karlien Coene and colleagues joined forces with scientists at the Radboud University’s FELIX laser laboratory. They published their findings in The Journal of Clinical Investigation.

Researchers identify missing ‘switch’ that controls expression of essential genes Published in Nature

8 July 2021

Michiel Vermeulen and colleagues identified that a long-sought-after transcription factor that regulates essential genes in the mouse and human genome. Published in Nature.

Radboud Pluim for Myrthe Swaak

8 July 2021

''Extraordinary accomplishments, strong commitment and a positive and constructive attitude” were the words used to praise senior communications advisor for science, Myrthe Swaak, when she received the Radboud Pluim.

RIMLS PhD retreat Registration open now!

8 July 2021

As announced previously, this year’s RIMLS PhD retreat will take place online from 17-19 Nov 2021, in collaboration with the New Frontiers Symposium.

Next Generation cytogenetics is on its way Does Optical Genome Mapping turn cytogenetics upside down?

7 July 2021

Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately.

Finding better ways to diagnose and treat IgA nephropathy

6 July 2021

IgA nephropathy is a slowly progressing disease that causes kidney damage and leads to kidney failure in about 25-50% of patients. The reason why some people develop IgA nephropathy is unclear and there is no effective treatment.

New culture method reveals how cancer cells bypass immune system

5 July 2021

Publication in Cancer Immunology Research

Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum in Nature Communcations

1 July 2021

Using complexome profiling Felix Evers, Taco Kooij and colleagues unravel the composition of mitochondrial oxidative phosphorylation complexes of asexual and sexual blood-stage malaria parasites, showing abundance differences and a metabolic switch central to gametocyte development and function.

DNA from 34-thousand-year-old skull helps research on the immune system

1 July 2021

Scientists at the Radboudumc have gained knowledge about genetic variation in the DNA of mankind of that time thanks to DNA research from a 34-thousand-year-old skull found in a Romanian cave.

Diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis in taskforce report

30 June 2021

Diagnosis and management of COVID-19 associated pulmonary aspergillosis (CAPA) is challenging, so Paul Verweij and colleagues set a goal to develop practical guidelines.

RIMLS introductory course: ''In the Lead of your PhD" Online and personal

29 June 2021

During last week’s introductory course, new RIMLS PhD candidates worked on personal development from a comfortable chair at home.

Biomarkers for pyridoxine-dependent epilepsy identified by untargeted metabolomics and infrared ion spectroscopy

24 June 2021

Karlien Coene, theme Metabolic Diseases, and colleagues published in the Journal of Clinical Investigation that untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy.

Magnesium deficiency increases the risk of cardiovascular disease in diabetic patients

21 June 2021

Publication in Diabetes Care.

Two science talents to foreign top institutes with Rubicon

21 June 2021

Rubicons for Michelle Brouwer and Guido van Mierlo

The international dataset for colorectal local excisions is published

16 June 2021

Iris Nagtegaal and colleagues presented their first paper on the colorectal cancer dataset and published this in the journal Gastroenterology.

Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis

15 June 2021

Intan Dewi and Frank van de Veerdonk published in Cell Reports Medicine that Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis.

ZonMw Open Competition Grants for several Radboud researchers

15 June 2021

Four teams including researchers from Radboudumc and Radboud University receive a ZonMw Open Competion grant. Each proposal has a maximum budget of 750K euros.

ZonMw Open Competition Grant for Annemiek van Spriel and Piet Gros

15 June 2021

Annemiek van Spriel, theme cancer development and immune defense, together with Piet Gros, Dept. of Chemistry, Utrecht University obtained a ZonMw Open Competition Grant to investigate IL-6 receptor structure and signalling in tumor cells.

Human microbiome could shed light on higher morbidity rate in minoritized populations The link between environmental inequities and disease may lie in the gut

15 June 2021

A study published in PNAS is the first to explicitly address the gut microbiome as a pathway to understanding how environmental inequities could lead to health disparities.

A tipping point in cancer-immune dynamics leads to divergent immunotherapy responses

8 June 2021

Jeroen Creemers and Johannes Textor published in the Journal for ImmunoTherapy of Cancer that a tipping point in cancer-immune dynamics leads to divergent immunotherapy responses and hampers biomarker discovery.

Radboud Pluim for Dagmar Eleveld-Trancikova Policy advisor of the three research institutes

8 June 2021

Radboudpluim for research policy adviser Dagmar Eleveld-Trancikova.

A hybrid in silico and tumor-on-a-chip approach to model targeted protein behavior in 3D microenvironments

2 June 2021

Valentina Palacio-Castañeda published in Cancers about modeling the behavior of targeted proteins in 3D microenvironments by approaching a hybrid in silico and tumor-on-a-chip.

Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses

2 June 2021

Rosanne van Deuren published her study in Genome Medicine which shows that functionally grouping common and rare genetic variants enables the elucidation IL-1-mediated biological mechanisms, specifically, for IL-1β and IL-6 cytokine responses induced by various stimuli.

European research project raises hopes in fight against rare diseases Solve-RD successfully established an innovative approach to jointly re-analyze genomic and phenotypic data from unsolved rare disease patients

1 June 2021

For the first time in Europe hundreds of rare disease experts team up to actively share and jointly analyze existing data from unsolved rare disease patients.

Vaccination with immune cells boosts immune system after stem cell transplantation

1 June 2021

Jesper van Eck van der Sluijs and other researchers have developed a method for growing different types of dendritic cells: the cells of the immune system that specialize in processing foreign substances (including tumor proteins) and presenting them to killer cells.

Aggressive periprocedural hydration + rectal NSAID: no reduction in incidence of post-ERCP pancreatitis

1 June 2021

Aggressive fluid hydration plus non-steroidal anti-inflammatory drugs versus non-steroidal anti-inflammatory drugs alone for post-endoscopic retrograde cholangiopancreatography pancreatitis (FLUYT): a multicentre, open-label, randomised, controlled trial.

4th ENABLE symposium a big success

27 May 2021

RIMLS PhD candidates co-organized this unique event with three other European research institutes (IRB Barcelona, CPR Copenhagen, SEMM Milan), which was facilitated by a competitive Horizon 2020 grant.

Lisanne Gommers nominated for James Lind Prize Your vote is needed

25 May 2021

Her PhD research entitled "Digesting the role of the gut microbiome in proton pump inhibitor (PPI)-induced hypomagnesemia'' has been nominated for the James Lind Prize. You can vote now until 8 June.

NWO-Groot grant awarded to Nico Sommerdijk for groundbreaking research with electron microscopy

21 May 2021

NWO Large grant awarded to Nico Sommerdijk and colleagues

First volunteers vaccinated with Radboudumc malaria vaccine

20 May 2021

Today a new vaccine against malaria, largely developed in Nijmegen, is being tested for the first time in volunteers at Radboudumc.

Intensive writing week - online from Radboud in'to Languages

19 May 2021

This course is for early-career researchers, such as PhD candidates and postdocs, who are writing an article or thesis.

Call for entries Eppendorf & Science Prize for Neurobiology 2021

18 May 2021

Are you or one of your colleagues doing great research? If so, then we encourage you to apply for the prestigious Eppendorf & Science Prize for Neurobiology.

COVID-19 associated coagulopathy - lessons after 1 year

17 May 2021

Jenneke Leentjens, Saskia Middeldorp, and colleagues, published a review on the current knowledge of COVID-19 associated coagulopathy and the role of antithrombotic therapies in the Lancet Haematology.

Call Dutch L’Oréal UNESCO for Women in Science fellowships

12 May 2021

The Fondation L’Oréal and UNESCO invite you to nominate eminent women scientists for the 2022 L’Oréal-UNESCO For Women in Science International Awards. Deadline 31 May 2021.

Dried pepper and video games: novel proteins to generate small RNAs

11 May 2021

Joep Joosten and colleagues determined the composition of PIWI protein complexes to provide novel insights into the piRNA pathway of virus-transmitting mosquitoes. They published this recently in Cell reports.

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