News items related to the Radboud Institute for Molecular Life Sciences.
H2020 grant for a new EATRIS flagship project on personalised medicine6 September 2019
EATRIS obtained funding for a new flagship project for sustainability and personalised medicine: EATRIS-Plus. Alain van Gool, Peter-Bram ‘t Hoen and Ariaan Siezen are co-PI’s and receive approximately 550 k€ from this 5M€ Horizon2020 infrastructure development grant.
A personal touch of Lenneke Cornelissen5 September 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Lenneke Cornelissen.
New technique boosts preclinical antibody research30 August 2019
Martijn Verdoes, theme Nanomedicine, and Bas van der Schoot, theme Cancer development and immune defense, developed a technique to engineer and produce antibodies quickly, easily and cheaply. The researchers published their results in the open access journal Science Advances.
Help us evaluate the improved design of the lab U-workspace in practice29 August 2019
We have built two examples of the redesigned lab U-workspaces in the Research Tower (M850) on the 6th and 7th floor. These so-called ‘mockups’ are experimental setups that enable all potential users to evaluate the re-design of the workspaces in practice.
Publication in Blood on CD37 mutations in lymphoma26 August 2019
Suraya Elfrink, in Annemiek van Spriel's research group Immune cell signaling, theme Cancer development and immune defense, published a manuscript in Blood reporting that tetraspanin CD37 is frequently mutated in patients with diffuse large B cell lymphoma occurring at immune-privileged sites.
University Teaching Prize for Joost Hoenderop26 August 2019
The prize is a reward for excellent teaching and consists of a certificate and a sum of €3000, two-thirds of which is to be spent on educational activities. The prize will be awarded on Monday 2 September when the 2019-2020 Academic Year is opened.
Publication in PNAS on dissecting EEC syndrome using single-cell RNA-seq22 August 2019
PhD candidates Eduardo Soares and Quan Xu in Jo Huiqing Zhou’s group in Molecular Developmental Biology, theme Reconstruction and regenerative medicine, have published a paper in PNAS on the disease mechanism of EEC syndrome using single-cell RNA-seq technology and patient-derived iPSCs.
NWO grant for a tissue-generating patch to close diaphragmatic defects21 August 2019
Willeke Daamen and Toin van Kuppevelt, theme Reconstructive and regenerative medicine, were recently awarded a 690 k€ grant by NWO, domain Applied & Engineering Sciences, for the development of advanced patches for closure of diaphragmatic defects in children with congenital diaphragmatic hernia.
Front cover Human Mutation21 August 2019
The MetaDome web server build to interpret genetic variants based on genetic tolerance and homologous protein domains is featured on the Cover of Human Mutation. MetaDome was developed by Laurens van de Wiel, Coos Baakman, Daan Gilissen, Joris Veltman, Gert Vriend and Christian Gilissen,
NWO grant to develop new biomaterials for improved regeneration of bone defects20 August 2019
Sander Leeuwenburgh, theme Reconstructive and regenerative medicine, and Roland Brock, theme Nanomedicine, were recently awarded with a grant of 581 k€ by NWO, domain Applied & Engineering Sciences, to develop new biomaterials for improved regeneration of bone defects.
Interested to supervise a bachelor student for a short period?25 July 2019
Are you interested in helping second year (bio)medical bachelor students in the first steps of their scientific development? Especially for PhD candidates this is a perfect opportunity to become involved in teaching/supervision!
Four Veni grants for junior RIMLS researchers22 July 2019
Four junior researchers, affiliated to the RIMLS, have each received a Veni grant of 250,000 Euro from NWO. Our researchers received this prestigious grant for their remarkable and original talent and their ability to carry out innovative research.
4,8 million euros for prevention of tuberculosis among people with diabetes in Africa16 July 2019
Reinout van Crevel and Lindsey te Brake have received European funding of 4.8 million euros to lead an international consortium to screen thousands of people with diabetes in Uganda and Tanzania for TB, and investigate the effect and costs of 3 months preventive treatment for TB.
Summer greetings from René Bindels5 July 2019
In this last newsletter before the summer break and before I wish you all a happy holiday, I would like to briefly summarize the first half of 2019 and especially look ahead to the interesting activities that will take place in the second half of the year.
Prostate cancer theranostics imaging, surgical guidance, and targeted photodynamic therapy5 July 2019
In Theranostics, Mark Rijpkema and colleagues present the development of a novel multimodal tracer that targets both preoperative imaging, surgical guidance, and targeted photodynamic therapy of PSMA-expressing prostate cancer.
Effects of prophylactic haloperidol on long-term quality of life in ICU Patients4 July 2019
In Anesthesiology, Paul Rood, Marieke Zegers and Mark van den Boogaard described that prophylactic haloperidol use does not affect long-term quality of life in critically ill patients at high risk for delirium.
Awarded KWF grants for Radboudumc researchers2 July 2019
The Dutch Cancer Society (KWF) has awarded 25.5 million euros to 50 new research projects in 16 different institutes. 8 grants are awarded to Radboudumc researchers. We congratulate our researchers with this funding and wish them success with their great work.
Jan Smit appointed as dean / vice chair27 June 2019
Professor Jan Smit, current head of the Department of Internal Medicine, will be appointed as dean and vice chair of the Radboud university medical center as of 1 August. Within the Executive Board, Jan Smit will be particularly tasked with the portfolio of education and research.
Midsummer night event very successful25 June 2019
Almost 300 PhD candidates and postdocs from DCMN, RIHS and RIMLS enjoyed an inspiring and tasty Midsummer Night Event. Dean a.i. Jan Smit opened the event, after which Louise Lagendijk presented about 'selfcare is healthcare and positive psychology’.
New opportunity for Henk Stunnenberg24 June 2019
After more than 22 years, Henk Stunnenberg, theme Cancer development and immune defense, has left the Radboud University, Dept. of Molecular Biology, to take up a position at the Prinses Maxima Centre for pediatric oncology in Utrecht. On Friday 5 July a farewell drink is being organized.
Radboudumc Master Prize for Mark van Goor18 June 2019
Mark van Goor, theme Renal disorders, received the Radboudumc Master Prize for his MSc thesis entitled “High-resolution structure of the renal calcium channel TRPV5 revealed with cryo-EM”, which was based on his internship at the lab of Prof. Yifan Cheng, USA.
Exome sequencing in routine diagnostics: a generic test for 254 patients with primary immunodeficiencies18 June 2019
Exome sequencing may provide a genetic diagnosis in a significant number of patients in a single genetic test. Alexander Hoischen and Mihai Netea, theme Infectious diseases and global health, and colleagues, published their results in Genome Medicine.
Lowering cholesterol is not enough to reduce hyperactivity of the immune system14 June 2019
In Cell Metabolism, Siroon Bekkering, theme Vascular damage, and colleagues, provide a novel potential explanation for the residual cardiovascular risk, related to persistent activation of the immune system in patients with hypercholesterolemia who are treated with statins.