Vici grant for Michiel Vermeulen Reading the epitranscriptome15 April 2021
Michiel Vermeulen, theme Cancer development and immune defense, has been awarded a Vici grant from the Netherlands Organisation for Scientific Research (NWO), one of the largest personal scientific awards in the Netherlands.
Anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity14 April 2021
Cell reports publication by Charles Dinarello and Mihai Netea and colleagues, theme Infectious diseases and global health, shows that the anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity.
Genetische pleister ‘remt’ blindheid in patiënten met Usher syndroom Leidse ProQR bouwt onderzoek Radboudumc verder uit14 April 2021
Het Leidse biotechbedrijf ProQR Therapeutics presenteerde deze week positieve resultaten van een klinische fase I/II studie met het molecuul QR-421a, een molecuul dat in de vroegste fase is ontwikkeld door onderzoekers van het Radboudumc
Cross communication between nephron segments by extracellular vesicles13 April 2021
In the FASEB Journal, Joost Hoenderop and other researchers, theme Renal disorders, demonstrated that purinergic signaling and αENaC mRNA expression is controlled by extracellular vesicles flowing along the nephron segments.
Autoantibody profiles in systemic sclerosis a comparison of diagnostic tests8 April 2021
The research of Ruben Smeets and colleagues in Autoimmunity showed high concordance of prevalent SSc-specific autoantibodies between different diagnostic assays. Further standardisation for low prevalent SSc-specific and SSc-associated autoantibodies is needed.
RIMLS PhD retreat. Save the date(s)! 8 & 9 July or 14 & 15 Oct 20211 April 2021
How much are we all longing for an old-fashioned RIMLS PhD retreat full of science, workshops and fun! In normal years, the RIMLS 2-day PhD retreat is held in April. This year, however, it is not yet definitive. Final decision will follow in May.
Rare and complex urology: Clinical overview of ERN eUROGEN25 March 2021
Wout Feitz and colleagues, theme Reconstructive & Regenerative Medicine, Department of Urology, Division of Pediatric Urology (Radboudumc Amalia Children’s Hospital) publish an article in European Urology which well indicates the impact of ERN developments.
Immunomodulatory aged neutrophils are augmented in blood and skin of psoriasis patients24 March 2021
A new study by Radboudumc researchers show that Psoriatic patients have a unique neutrophil profile in circulation, and two distinct neutrophils subsets are present in psoriatic skin. The results are published in the Journal of Allergy and Clinical Immunology on the 19th of March.
Discovery of new protein with an important role in atherosclerosis11 March 2021
Atherosclerosis is the underlying condition that causes heart attacks and strokes. Researchers at Radboudumc in the Netherlands have discovered a protein that appears to play an important role in atherosclerosis. The protein is called Prosaposin.
Benjamin Mordmüller10 March 2021
Ever since he realized about three decades ago that science was his fate, fighting neglected tropical diseases has become his fierce battle. When he’s not actively saving the world, he’s a devoted musician. Let’s get to know this new member of our research family better.
Researchers grow most lifelike bone organoid to date Greatly increasing our understanding of bone formation and bone diseases9 March 2021
Researchers from Radboudumc and Eindhoven University of Technology have interwoven various bone cells into an 'organoid' that can independently make new, hard bone tissue. It’s the most complete 3D model of bone formation to date. Peaked your interest? Read more!
Online, socially distanced, or pre-pandemic style... “In the Lead” is always inspiring and helpful. By Özlem Bulut25 February 2021
Every new RIMLS PhD candidate shares one common experience: an amazing 2-day retreat where you make friends, discover yourself, and get inspired. At least, that was the case pre-pandemic. No more communal retreats in an old convent, but the course still continues helping new PhDs online.
Trained immunity: a tool for reducing susceptibility to and the severity of SARS-CoV-2 infection17 February 2021
In a review in Cell Mihai Netea, Frank van de Veerdonk, Reinout van Crevel and Jorge Dominguez Andres propose that induction of trained immunity by whole-microorganism vaccines may represent an important tool for reducing susceptibility to and severity of SARS-CoV-2.
Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates9 February 2021
Gert-Jan Veenstra and Simon van Heeringen published in the Embo Journal. Their results show that transcription factors cooperate in a combinatorial fashion in generally open chromatin to orchestrate zygotic gene expression.
Vacancy in RIMLS PhD Council3 February 2021
Enthusiastic PhD candidates wanted to expand the RIMLS PhD Council, which consists of an active group of young researchers and different tasks are carried out in subgroups. Would you like to organize social or scientific activities for PhD candidates together with colleagues? Make your voice count!
ZonMw grants to study optimal use of COVID-19 vaccines in patients with impaired immune systems3 February 2021
How do people with reduced immunity, especially kidney patients, react to a COVID-19 vaccination? And how can patients with peripheral arterial disease be helped by DNA testing? Our researchers received grants from ZonMw to make these studies possible.
Establishing the biggest database of pathology images to accelerate the development of artificial intelligence in medicine.2 February 2021
A new consortium of the EU Innovative Medicines Initiative (IMI) aims to establish the biggest database of pathology images to accelerate the development of artificial intelligence in medicine.
Increase radio- and immunotherapy efficacy by targeting hypoxia21 January 2021
In a paper recently accepted by Clinical Cancer Research, Daan Boreel, together with Paul Span, Sandra Heskamp, Gosse Adema and Jan Bussink, reviews the therapeutic potential of decreasing the lack of oxygen (hypoxia) often found in solid tumors.
New research through grants for Radboudumc researchers14 January 2021
Several researchers at the Radboudumc have received grants to start new studies, including on rare diseases, liver disease and cancer metastases. These are grants from the Dutch Research Council, European Joint Programme on Rare Diseases and the Gastric Liver Disease Foundation.
RIMLS online award ceremony proudly presenting the winners13 January 2021
In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony.