Increase radio- and immunotherapy efficacy by targeting hypoxia21 January 2021
In a paper recently accepted by Clinical Cancer Research, Daan Boreel, together with Paul Span, Sandra Heskamp, Gosse Adema and Jan Bussink, reviews the therapeutic potential of decreasing the lack of oxygen (hypoxia) often found in solid tumors.
New research through grants for Radboudumc researchers14 January 2021
Several researchers at the Radboudumc have received grants to start new studies, including on rare diseases, liver disease and cancer metastases. These are grants from the Dutch Research Council, European Joint Programme on Rare Diseases and the Gastric Liver Disease Foundation.
RIMLS online award ceremony proudly presenting the winners13 January 2021
In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony.
Hermesdorf Prizes for COVID-19 research team and Charlotte Bekker7 January 2021
The entire COVID-19 research team at Radboudumc, which includes Frank van de Veerdonk, Mihai Netea, Roger Brüggemann, Leo Joosten and Alexander Hoischen, will receive the 2020 Hermesdorf Prize. Charlotte Bekker will be awarded the Hermesdorf Talent Prize.
1.6 million Euro for COHERENT to improve the diagnosis and treatment of blood cancer29 December 2020
The Dutch Cancer Society KWF has granted 1.6 million Euro to COHERENT a Dutch platform for the development of new diagnostic technologies for rare hematological (blood) cancers. COHERENT is an initiative from Radboudumc, AmsterdamUMC and ErasmusMC.
NWO ENW KLEIN grant awarded to Koen van den Dries and Michiel Vermeulen22 December 2020
Koen van den Dries will investigate the molecular mechanisms of actin isoform usage in cancer cell migrations. Michiel Vermeulen will search for proteins that interact with adenosine diphosphate ribose chains and play a role in the cellular response to damage to DNA.
Targeting of radioactive platinum-bisphosphonate anticancer drugs to kill cancer cells in bone tumors15 December 2020
Sander Leeuwenburgh and his team, theme Reconstructive and regenerative medicine, showed in a recently accepted paper (Materials Today Bio) that radioactive platinum-based anticancer drugs can be targeted towards bone tumors to killl tumor cells inside these tumors.
Enthusiasm among young researchers for the new Recognition and Rewards System10 December 2020
Do you think we assess each other adequately and justly at Radboudumc? How can we create a more collaborative environment that would foster scientific integrity? These questions were discussed at the Research Integrity Round titled ‘Recognition and Rewards for Radboudumc Academics’ on December 9.
Working energetically from home3 December 2020
By now, you may have gotten used to it: working from home. The page ‘Working energetically from home‘ offers you tips to help you work from home better, from setting up a good workspace to working more effectively and maintaining a good work-life balance.
Controlled human malaria infection induces long-term functional changes in monocytes3 December 2020
Robert Sauerwein and Henk Stunnenberg together with Mihai Netea and other colleagues now show for the first time that even a parasitic infection can train the immune system. The article is published in Frontiers in Molecular Biosciences.
Radboudumc research most lungs recover well after COVID-1926 November 2020
In severe COVID-19 patients the lung tissue recovers well in most cases. This is shown in research by the Radboudumc, published in Clinical Infectious Diseases. Striking conclusion: patients who were referred by the general practitioner recover worse than ICU patients.
Cell spreading is hard work Bioenergetics of stem cell mechanoresponses in Biomaterials12 November 2020
The study of Bioenergetics of stem cell mechanoresponses, published in Biomaterials is carried out in a collaboration between Werner Koopman, theme Metabolic Diseases, and colleagues from the Radboud University and California Institute of Technology.
967K Euro grant to develop organoids enabling new research methods for skin disorders11 November 2020
Ellen van den Bogaard will lead a consortium, financed by Health Holland, to establish a platform in which materials and technologies are developed to stimulate research with so-called skin organoids, small pieces of cultured skin.
Reprogramming of bone marrow myeloid precursor cells in patients with severe coronary artery disease10 November 2020
Exploratory ''first-in-man'' study adds a new dimension to the role of our innate immune system in the development of cardiovascular disease. This study from Niels Riksen and colleagues is published in Elife.
Veni grants for six Radboudumc researchers5 November 2020
The Netherlands Organization for Scientific Research (NWO) has awarded a Veni grant to six young researchers at Radboudumc, Pascal Miesen, Isabella Wagner, Janita Bralten, Jorge Dominguez Andres, Elin Svensson and Else Eising. This funding will enable them to further develop their research.
Ronald de Groot receives royal decoration as Knight in the Order of Oranje-Nassau.4 November 2020
Ronald de Groot receives royal decoration as Knight in the Order of Oranje-Nassau because of his exceptional contribution to pediatrics, in particular pediatric infectious diseases. He has used his influence, position and experience to help the most vulnerable in our society.
Two studies show potential of trained immunity for the treatment of cancer Radboudumc makes Cell twice in one issue29 October 2020
Mihai Netea: "These studies show that stimulating trained immunity can have an important anti-cancer effect. In combination with current immunotherapy with 'checkpoint inhibitors', boosting trained immunity has the potential to significantly improve cancer treatment"