Study into better protection for healthcare workers against coronavirus infection19 March 2020
Radboudumc and UMC Utrecht will investigate whether health care workers are better protected against the coronavirus after a vaccination against tuberculosis (BCG vaccine). This vaccine does not directly protect against the coronavirus, but provides a boost to the immune system.
Differences in the placental disposition of TNF inhibitors uncovered19 March 2020
In Clinical Pharmacology and Therapeutics, researchers from the Depts. of Pharmacology and Toxicology, Obstetrics and Gynecology, and Health Evidence, in collaboration with Sanquin Diagnostic Services, investigated the placental handling of the TNF inhibitors infliximab and etanercept.
Register for pilot peer coaching for RIMLS PhD candidates17 March 2020
Obtaining your PhD can be a difficult task. In a peer coaching group (“intervisie groep”) you can discuss your (non-technical) problems or dilemmas in a structured way with peers. You can now register for the RIMLS pilot with PhD peer coaching groups. Extended deadline 15 May 2020.
Interleukin-37 plays a rol in the pathogenesis and treatment of gout11 March 2020
RIMLS researchers Leo Joosten, Viola Klück and Rosanne van Deuren, in collaboration with the Dept. of Human Genetics, discovered that rare genetic variants in interleukin-37 link the anti-inflammatory cytokine to the pathogenesis and treatment of gout.
NWO Open Competition ENW - KLEIN grant for Jenny van der Wijst9 March 2020
KLEIN grants offer researchers the possibility to realize curiosity-driven, fundamental research and elaborate creative and risky ideas. For this project, Jenny is seeking an enthusiastic postdoc to join her team working on ion channels.
FET-OPEN grant for Toin van Kuppevelt and Willeke Daamen6 March 2020
A grant of 592 kEuro has been awarded to Toin van Kuppevelt and Willeke Daamen, theme Reconstructive and regenerative medicine, for a Horizon 2020 FET-OPEN project entitled “Heparin and heparan sulphate: from sequence determination to therapeutic strategies for Parkinson’s disease”.
Plugging the gap ZonMw/Health Holland grant3 March 2020
RIMLS en RIHS researchers Willeke Daamen, Frank Vandenbussche, Joris van Drongelen, Toin van Kuppevelt and Janneke Grutters have been granted 1.3 million euro for the development and evaluation of a new technology to prevent premature rupture of fetal membranes (iPPROM).
Guiding the surgeon real-time tumor visualization during surgery26 February 2020
Incomplete excision of tumor tissue negatively affects the prognosis of the patient. RIHS researcher Mark Rijpkema and colleagues are working on the development of new dual-labeled tracers and currently are implementing this into the clinic.
NWO open call GROOT grant for Michiel Vermeulen24 February 2020
Michiel Vermeulen, theme Cancer development and immune defense, received a 300,000 EUR grant within the NWO-GROOT consortium. He will use mass spectrometry-based proteomics and interaction proteomics applications to study proteome and gene expression dynamics during early C. Elegans development.
Researchers investigate how stem cells affect the immune system18 February 2020
RIMLS researchers Irma Joosten and Renate van der Molen, participating in an European study into the treatment of brain damage in premature babies. Is it possible to limit or even partly repair the damage with stem cells? They focus primarily on the effect of those stem cells on the immune system.
Five ZonMw ‘Off Road’ grants for Radboudumc researchers17 February 2020
Benoit Besson, Annemarie Boleij, Jonne Doorduin, Jorik Nonnekes and Sara Roig Merino have each received an ZonMw ‘Off Road’ grant of €100,000. The grants are intended for biomedical health researchers who dare to go off the beaten track in their search for new insights and unexpected breakthroughs.
Dutch Kidney Foundation PhD grant for Johan van der Vlag and Tom Nijenhuis14 February 2020
Johan van der Vlag and Tom Nijenhuis, theme Renal disorders, received this grant for their joint research project “Targeting a novel paracrine signaling pathway between glomerular endothelium and podocytes to treat glomerular injury”.
Interactive career day for Postdocs and PhD candidates13 February 2020
45 Postdocs and PhD candidates attended the first Interactive career day organised by Janssen Pharmaceutica, to learn more about career perspectives and R&D activities that on the longer term can lead to ideas and potential future collaboration.
Khondrion begins study on optimal dosage of new drug10 February 2020
Pharmaceutical company Khondrion, a spin-off from Radboudumc, has taken another important step in the development of its drug sonlicromanol. The first patients have used the drug as part of a phase 2b study, which focuses on determining the optimum dose and efficacy.
Human pDCs attract cytolytic lymphocytes in anti-cancer vaccination6 February 2020
RIMLS researchers Jasper van Beek and Jolanda de Vries, theme Cancer development and immune defense, discovered that pDCs can efficiently recruit cytolytic immune effector cells, a property that could be exploited in anti-cancer vaccines. They have published these findings in Cell Reports.
Research Integrity Round with Frank Miedema6 February 2020
Guest speaker on 9 March 2020 is Frank Miedema, Vice Rector for research and chair of the Utrecht University Open Science program. He is one of the initiators of Science in Transition. All students, PhD candidates and senior researchers are invited to attend. Please register via the website.
ZonMw funding for teams of Michiel Vermeulen and Jolanda de Vries4 February 2020
The awarded research projects of RIMLS researchers Michiel Vermeulen, Jolanda de Vries, Gerty Schreibelt and Martijn Verdoes and colleagues will initiate new research lines and collaborations between various research groups.
RIMLS PhD retreat registration is open23 January 2020
Yearly, RIMLS PhD candidates gather for the two-day PhD Retreat. Apart from the science, this event is highly valued for the opportunity to meet and get to know fellow PhD candidates during the social activities. Early bird registration and abstract submission deadline: 4 March 2020.
NWO Open Competition Domain Science - XS grant for Ronald van Rij and Jenny van der Wijst21 January 2020
NWO Domain Science has awarded Ronald van Rij, theme Infectious diseases and global health and Jennny van der Wijst, theme Renal disorders an XS grant. The XS category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea.
Stofwisselkracht grant for Daan Panneman and Richard Rodenburg16 January 2020
Daan Panneman & Richard Rodenburg have been awarded a Stofwisselkracht grant for their proposal “CRISPR/Cas9 knock-in complementation in fibroblasts of mitochondrial disease patients”. Together with Omar Tutakhel & Jan Smeitink they will investigate the possibility of using CRISPR/Cas9 knock-in.
Radboud Talks 2020 deadline registration 3 February 202014 January 2020
The next edition of Radboud Talks will take place in the spring. During this academic pitch competition, young researchers will be given the opportunity to share their stories with a large audience. In a three-minute presentation, you will talk about your research in a fun and accessible manner.
Rubicon Grant for Sami Mohammed14 January 2020
Former RIMLS researcher Sami Mohammed, theme Renal disorders, received a Rubicon Grant from the Dutch Organisation for Scientific Research (NWO). The Rubicon program gives young, highly promising researchers the opportunity to gain international research experience.
Review Sanne Frambach accepted by Pharmacological Reviews13 January 2020
In this review entitled 'Brothers in arms: ABCA1 and ABCG1-mediated cholesterol efflux as promising targets in cardiovascular disease treatment', RIMLS researcher Sanne Frambach, describe the possibilities for stimulating cellular efflux.
p120-catenin-dependent collective brain infiltration by glioma cell networks7 January 2020
Pavlo Gritsenko and Peter Friedl, theme Cancer development and immune defense, report in Nature Cell Biology, that glioma cells infiltrate the brain by a collective network mechanism, which critically depends on p120 catenin. p120 thus represents a potential target to combat glioma.
Resistance of malaria parasites against artemisinin explained7 January 2020
Malaria parasites that are resistant to the commonly used malaria medicine artemisinin are a growing problem. How these parasites become resistant has now been uncovered by the RIMLS group of Richard Bartfai, theme Infectious diseases and global health, and published in Science.
JPI-AMR grant for Quirijn de Mast and Marien de Jonge6 January 2020
The JPI-AMR grant ‘Diagnostics and surveillance of antimicrobial resistance: development of tools, technologies and methods for global use’ has been awarded to Quirijn de Mast and Marien de Jonge), the Charles University Prague and the Kilimanjaro Christian Medical Centre in Moshi, Tanzania.
Niels Stensen Fellowship for Jorieke Weiden6 January 2020
Jorieke Weiden was recently awarded a grant from the Niels Stensen Fellowship. Since the 1960s, the Niels Stensen Fellowship has been awarded annually to outstanding researchers who recently received their PhD to enable them to gain research experience at a top university or institute abroad.
UMC consortium brings Digital Research Environment to next phase19 December 2019
Radboudumc, Erasmus MC and UMC Utrecht will work together to bring the Digital Research Environment to the next phase. The ultimate goal: to make this online environment for the secure and fast management, analysis, sharing and storage of research data a national and international success.
Awarded KWF grants for Radboudumc researchers18 December 2019
KWF is investing 2.7 million euros in five different studies at Radboudumc. The awards are part of the new round of funding by DCS, in which over 34 million euros will be granted to Dutch cancer research. We congratulate our researchers with this funding and wish them success with their great work.
Kolff grants Dutch Kidney Foundation for Raphaël Duivenvoorden and Jitske Jansen17 December 2019
The Dutch Kidney Foundation supports talented postdocs and physician researchers through providing personal grants that support different phases of a research career. This year Raphaël Duivenvoorden and Jitske Jansen, theme Renal disorders, received a Kolff grant.
Galectin-9 controls plasma membrane integrity of dendritic cells16 December 2019
Laia Querol Cano, theme Cancer development and immune defense, has discovered how galectin-9, a sugar-binding membrane organiser, governs dendritic cell function by intracellularly modulating actin cytoskeleton. These findings are published in the latest issue of iScience.
PPP allowance by Health~Holland for Fons van de Loo16 December 2019
Fons van de Loo, theme Inflammatory diseases, has been granted a 3 year PPP Allowance made available by Health~Holland for the project ‘REFIT’. The goal of this project is to restore the barrier function, immunity and microbiome of the intestinal tract using extracellular vesicles from milk.
New insights into the initiation of T cell responses in the spleen11 December 2019
Carl Figdor and colleagues, theme Cancer development and immune defense, provide insights into the initiation of T cell responses in the spleen and their consequences for T cell differentiation. They have published their results in Proceedings of the National Academy of Sciences USA.
A personal touch of Marieke Willemse10 December 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Marieke Willemse.
Dietrich-Knorr Prize for Hedi Claahsen-van der Grinten10 December 2019
Hedi Claahsen-van der Grinten, theme Vascular damage, received the Dietrich-Knorr prize 2019 for the best published paper in the field of adrenal research, for her publication in the Journal of Clinical Endocrinology & Metabolism.
Help wanted to organize our New Frontiers Symposium9 December 2019
Are you a 1st or 2nd year PhD candidate with the ambition to organize an international symposium? The organizing committee of the RIMLS New Frontiers Symposium of 2021 dedicated to Glycobiology is looking for two PhD candidates who are interested to participate in the organization.