News RIMLS

Genetic mutations cause severe magnesium deficiency

Newly discovered errors in DNA change diagnostics and treatment. Jeroen de Baaij tracked down new genetic errors that cause magnesium deficiency and published the findings in the Journal of the American Society of Nephrology.

Tom Nijenhuis appointed professor of Rare Kidney Diseases

Wanted: RIMLS PhDs to organize ENABLE symposium in Seville in November 2022

Ever thought it could be fun to organize a scientific symposium? Want to improve your CV? Want to collaborate with international PhD candidates? Want to get in contact with biomedical companies? Ever felt lost at a conference because of too little focus on young researchers?

Best presentation award for Felicitas Pardow at the European Epidermal Barrier Research Network

During the annual meeting of the European Epidermal Barrier Research Network (E2BRN) recently, Felicitas Pardow received the best presentation award.

Antibodies are sustained in nasal fluid after mild corona infection

Testing through nasal fluids is easier than through blood

Large AI project receives over €95 million for ten years of public-private research

The Dutch Research Council (NWO) is to fund two consortia for a period of ten years. Radboudumc participates in the ROBUST consortium, which consists of 17 AI labs, eight of which are dedicated to healthcare. Radboudumc leads five of these eight labs.

Reading ADP-ribosylation signaling using chemical biology and interaction proteomics published in Molecular Cell

Kasia Kliza and Michiel Vermeulen worked on a project to synthesize biotinylated ADPr-based probes that can identify ADPr readers and determine their specificity for mono- and polyADPr. They published this in Molecular Cell.

Systematic analysis of short tandem repeats in 38,095 exomes provides an additional diagnostic yield

Christian Gilissen and colleagues published in Genetics in Medicine about their work guiding the application of short tandem repeat analysis in clinical exome sequencing.

TropIQ seeks new mosquito repellents

TropIQ Health Sciences, a Radboudumc spin-off, has received a 1.3 million USD grant from the Bill & Melinda Gates Foundation to track down new mosquito repellents.

Young Radboudumc researchers receive grant to engage in bio-medical and health research that is off the beaten path

The ZonMw Off Road program is once again giving young scientists the opportunity to conduct innovative research in medical and/or health care. This research is off the beaten track and aims to bring about new insights and unexpected breakthroughs for healthcare and healthcare innovation.

Infections increase risk to develop dementia

In a recently published study, Radboudumc researchers investigated the effects of infectious events on cognitive decline and the development of dementia and its possible structural underpinning using pre- and post-infection MRI of the brain.

Young Investigator Award for Alex Garanto

Alex Garanto has been honored with the 2021 Mary Ann Liebert, Inc. publishers Young Investigator Award

ENABLECARES launches a course on entrepreneurship for PhD candidates and postdocs

Are you thinking about what to do after your PhD? Want to know more about entrepreneurship? This course gives you insight in many aspects of entrepreneurship and research in industry.

Effectiveness and predictors of response to somatostatin analogues in patients with gastrointestinal angiodysplasias

Lia Goltstein and colleagues published a study about effectiveness and predictors of response to somatostatin analogues in patients with gastrointestinal angiodysplasias: a systematic review and individual patient data meta-analysis.

Cooperating T cells clear tumor cells more effectively

Live imaging: immune cells attack tumor

Genetic archaeology reveals major changes in the immune system

Evolution of the immune system unraveled based on ancient DNA

Tackling cancer with radioactive particles

Professor Sandra Heskamp receives grant for research into cancer treatment with radioactivity

Three groundbreaking Radboud projects launched through NWO open competition

Three groundbreaking research projects at Radboudumc and Radboud University have been awarded grants of up to 50,000 euros through NWO's ENW - XS Open Competition.

New Frontiers symposium on Translational Glycoscience Last chance for early bird registration

Register now for our annual New Frontiers Symposium (18 & 19 November 2021) on current advances in glycobiology.

Unraveling piRNA-mediated degradation of viral RNA in vector mosquitoes published in Nucleic Acids Research

Joep Joosten and colleagues have published their discoveries about a new molecular mechanism with important implications for our understanding of the mosquito immune system and its role in controlling transmission of viruses.

Photosensitizer-based multimodal PSMA-targeting ligands for intraoperative detection of prostate cancer

Sandra Heskamp and Yvonne Derks published in Theranostics that photosensitizer-based PSMA-targeting ligands can be used for intraoperative detection and treatment of prostate cancer.

Genetic diagnosis in hereditary hemochromatosis discovering and understanding the biological relevance of variants

Floor Baas and Dorine Swinkels, theme Renal Disorders, published about assessment of pathogenicity of genetic variants in hereditary hemochromatosis.

Fresh postdoc wanted for RIMLS Graduate School committee

Do you want to use your experience as a RIMLS PhD candidate for the next generation?

Call for Research at InScience Filmfestival Register before 16 September 2021

ENABLE continues New funding guarantees four more international conferences by and for young researchers

Thanks to sponsoring of FEBS (Federation of European Biochemical Societies) and IUBMB (International Union of Biochemistry and Molecular Biology), ENABLE’s success formula can be continued for four more years. That means: four more gatherings full of science, career options, outreach and fun.

Off the shelf proximity biotinylation for interaction proteomics

Irene Santos-Barriopedro and Michiel Vermeulen, theme Cancer development and immune defense, published an off-the-shelf proximity biotinylation enzyme for interaction proteomics.

KNAW Ter Meulen grants for Radboudumc researchers

Four young researchers of the Radboudumc in the field of pediatrics and related fields can go abroad for a scientific research project/work visit in the coming year with a KNAW Ter Meulen grant.

Research into treatment for bladder pain syndrome will now be reimbursed

Bladder pain syndrome, also called interstitial cystitis, is a chronic benign condition of the urinary bladder

More variants TLR7 gene found in young healthy men with severe Covid-19 Screening and accelerated vaccination for TLR7 immunodeficiency

Spanish-Dutch research has revealed two new mutations in the TLR7 gene in healthy young men who became seriously ill with severe Covid-19.

Jeroen de Baaij Appointed associate professor

We are happy to announce that Jeroen de Baaij has been appointed associate professor of Kidney Physiology.

Senior Kolff Fellowship for Jeroen de Baaij

Jeroen de Baaij, theme Renal disorders, received a prestigious Senior Kolff grant from the Dutch Kidney Foundation. His project aims to establish dietary approaches against vascular calcification in chronic kidney disease.

Differences in the number of de novo mutations between individuals due to small family-specific effects and stochasticity

Christian Gilissen and colleagues investigated whether there is a family-specific contribution to the number of de novo mutations in the DNA of offspring and published the results in the Genome Research.

Christa Sperna Weiland, Erwin van Geenen and Joost Drenth discuss the best strategy to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis

Christa Sperna Weiland, Erwin van Geenen and Joost Drenth, published in Lancet Gastroenterology & Hepatology a systematic review and network meta-analysis to determine the most efficacious prophylaxis strategy to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis.

ZonMw Gender in Research competition awarded to Genderful Research World Consortium

Natalia Valdrighi and Esmeralda Blaney Davidson won the competition to create a plan for the dissemination of the knowledge and skills gained during the Gender in Research workshop amongst their peers, colleagues and institution, financed by ZonMw and CIHR-IGH in Canada.

Young people with colorectal cancer deserve their own treatment

Richarda de Voer and Marjolijn Ligtenberg's study on clinical, pathological, genetic and molecular characteristics of colorectal tumors in adolescents and adults 25 years of age or younger is published in Clinical Gastroenterology and Hepatology.

Nijmegen literally puts Digital Health on the map Flourishing ecosystem gets its own interactive overview

Digital Health is thriving in the Nijmegen region, where it contributes to better care and health and also creates jobs. To bring developers and end users even closer together, The Economic Board and the Radboudumc are introducing the Interactive Digital Health map.

Michiel Vermeulen and Klaas Mulder receive funding from ZonMw for a collaborative project using stem cell-based models

Michiel Vermeulen and Klaas Mulder, theme Cancer development and immune defense, receive funding from ZonMw for a collaborative project to develop a stem cell based model to study early human embryogenesis.

ZonMw funding for PSIDER program

Michiel Vermeulen, Klaas Mulder and Nael Nadif Kasri receive funding from ZonMw for a collaborative project to develop a stem cell based model to study early human embryogenesis.

Happy summer greetings from René Bindels

Before most colleagues enjoy their well-deserved summer break, I would like to briefly share these wishes with you...

VIDI grants for researchers of Radboud university medical center

Several Radboudumc researchers have been awarded a VIDI grant by the Dutch Organisation for Scientific Research (NWO). They each receive a sum of 800,000 euros, which they will use over the next five years to develop their own innovative line of research and to set up a research group.

Sonlicromanol seems promising for certain cancers Khondrion announces publication in PLOS ONE of new research

Khondrion announces publication in PLOS ONE of new research showing normalisation of prostate cancer stem cell mPGES-1 overexpression and inhibition of cancer spheroid growth by sonlicromanol’s active metabolite.

Newborn screening in sight through the discovery of novel disease biomarkers by new technique

To identify new biomarkers that can be used in the newborn screening protocol, also known as the neonatal heel prick, Karlien Coene and colleagues joined forces with scientists at the Radboud University’s FELIX laser laboratory. They published their findings in The Journal of Clinical Investigation.

Researchers identify missing ‘switch’ that controls expression of essential genes Published in Nature

Michiel Vermeulen and colleagues identified that a long-sought-after transcription factor that regulates essential genes in the mouse and human genome. Published in Nature.

Radboud Pluim for Myrthe Swaak

''Extraordinary accomplishments, strong commitment and a positive and constructive attitude” were the words used to praise senior communications advisor for science, Myrthe Swaak, when she received the Radboud Pluim.

RIMLS PhD retreat Registration closed.

Fun and Science come togther during the online RIMLS PhD retreat on 17-19 November, which is organized togeher with the New Frontiers Symposium. Register and upload your abstract quickly!

Next Generation cytogenetics is on its way Does Optical Genome Mapping turn cytogenetics upside down?

Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately.

Finding better ways to diagnose and treat IgA nephropathy

IgA nephropathy is a slowly progressing disease that causes kidney damage and leads to kidney failure in about 25-50% of patients. The reason why some people develop IgA nephropathy is unclear and there is no effective treatment.

New culture method reveals how cancer cells bypass immune system

Publication in Cancer Immunology Research

Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum in Nature Communcations

Using complexome profiling Felix Evers, Taco Kooij and colleagues unravel the composition of mitochondrial oxidative phosphorylation complexes of asexual and sexual blood-stage malaria parasites, showing abundance differences and a metabolic switch central to gametocyte development and function.

DNA from 34-thousand-year-old skull helps research on the immune system

Scientists at the Radboudumc have gained knowledge about genetic variation in the DNA of mankind of that time thanks to DNA research from a 34-thousand-year-old skull found in a Romanian cave.