News RIMLS

A single protein complex balances the very first lineage decision of cells in human: towards foetus or placenta

The international group of researchers spearheaded by Dick Zijlmans and Hendrik Marks together with colleagues from KU Leuven, examined which proteins are associated with the chromatin and how this affects gene transcription.

Registration is open for the international PhD retreat in Barcelona

Do you love PhD retreats? Do you want to know what these are like in other institutes? The Institute for Research in Biomedicine (IRB) in Barcelona is organizing a PhD retreat on 21 and 22 October 2022 in Barcelona.

In the lead of your PhD RIMLS introduction course

Within 1.5 days, 15 new PhD candidates from many departments created a very good start of their PhDs.

‘Happiness is in the small things’ a throwback to the valedictory lecture of René Bindels

In a full Aula he outlined his scientific journey of the past 40 years that led to the groundbreaking discovery of the transient receptor potential ion channel TRPV5 that plays an essential role in maintaining the calcium balance in our body.

Dutch Society of Clinical Chemistry Science & Innovation Award for the team of Hans Jacobs

The team of Hans Jacobs pioneers on the development of personalized diagnostics to measure minimal residual disease in patients with multiple myeloma.

The consortium 'OAInject' has been awarded a grant within NWO's 'Perspectief' program for research into the treatment of osteoarthritis

The 'OAinject' consortium, in which Peter van der Kraan is involved as one of the Work Package leaders, received the NWO 'Perspectief' grant to develop new diagnostic tools that determine exactly what form of osteoarthritis someone has to enable tailor-made treatments.

Parasitology prize for researcher Matthijs Jore Boehringer Ingelheim Parasitology Award for malaria vaccine research

Field research on malaria vaccine offers unexpected surprise

Field research on the effectiveness of a malaria vaccine, came up with unexpected results for an international group of researchers including Benjamin Mordmüller of Radboudumc. The vaccine evokes a broader response against malaria proteins than there are in the vaccine.

The future of laboratory animal research More attention to living conditions of laboratory animals

On May 9, a meeting took place at the Radboudumc as a result of the launch of the Dutch Transparency Agreement on Animal Testing. The Radboudumc is one of the twenty signatories and has thus committed itself to openly and transparently communicate its vision and policy with regard to animal testing.

Jolanda de Vries and Teun Bousema appointed member of KNAW

Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling

Bart Smeets, Jitske Jansen and collegues, theme Renal disorders published this article in the Human Development.

Renee Salz wins prize for best presentation

Renee Salz won the award for best oral presentation during the Rolduc genetics retreat, organized by the Dutch and Belgian Societies of Human Genetics in Brugge. Her presentation was titled "Variant effect prediction based on long read transcriptomes".

Mani Diba joins the Department of Dentistry as Hypatia Tenure Track Fellow

Mani Diba recently re-joined Radboudumc as an Hypatia Tenure Track Fellow at the research group Regenerative Biomaterials of the Department of Dentistry.

Combining targeted radionuclide therapy and immune checkpoint inhibition for cancer treatment

Simone Kleinendorst, Sandra Heskamp and colleagues, theme Rare cancers, published in Clinical Cancer Research about their research on combined radionuclide therapy and immunotherapy for cancer treatment.

European grants for groundbreaking Radboudumc research Professors Roshan Cools and Peter Friedl receive ERC Advanced Grant

The European Research Council (ERC) is awarding grants to Roshan Cools and Peter Friedl, both professors at Radboudumc. While Cools will investigate how brains control behaviour in (stressful) situations, Friedl will work on developing a new cancer therapy.

New malaria drug is ready for testing in humans Drug kills malaria parasite and blocks transmission of parasite to mosquito

Saponin-based adjuvant-induced dendritic cell cross-presentation is dependent on PERK activation published in Cellular and Molecular Life Sciences

Lisa Huis in ‘t Veld, Nataschja Ho and colleagues from the team of Gosse Adema published in Cellular and Molecular Life Sciences that Saponin-based adjuvant-induced dendritic cell cross-presentation is dependent on PERK activation.

Camille Le Gall reports an efficient approach for delivery of poorly soluble tumor antigens to human cDC1s

Camille Le Gall published about an efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion in the Journal of Immunotherapy of Cancer.

Rubicon grants awarded to three RIMLS researchers

Three researchers have received Rubicon funding from NWO/ZonMw. This will enable Elke Muntjewerff, Laura de Vries and Laurens van de Wiel to do research at a foreign research institute for the next two years.

Poster prize for Valerie Betting

At the recent EMBO Workshop PIWI proteins and piRNAs, Valerie Betting, theme Infectious Diseases & Global Health, won a poster prize for her poster Elucidating the role of Yb in PIWI4/tapiR-mediated gene silencing.

A "QR code" to read metabolism inside prostate cells: labeled extra-cellular citrate

In a recent publication in the Proceedings of the National Academy of Sciences USA, Frits van Heijster and his colleagues describe investigations to uncover which carbon sources and metabolic pathways are used by epithelial cells of the prostate to sustain high luminal citrate levels.

Patient must give explicit consent Request for permission to use medical data, leftover human biomaterial and images

Neolithic made us taller and more intelligent, but more prone to heart disease How modern European populations have evolved over the past 50,000 years

After the Neolithic, European populations showed an increase in height and intelligence, reduced skin pigmentation and increased risk of cardiovascular disease due to genetic changes that lowered concentrations of 'good' HDL cholesterol.

Joyce Aarts and colleagues published in Scientific Reports about the role of TGF-β1 in (experimental) arthritis

Joyce Aarts, theme Inflammatory diseases, and her colleagues published in Scientific Reports, that local inhibition of TGF-β1 signaling improves Th17/Treg balance but not joint pathology during experimental arthritis.

Large NWA ORC grant awarded for national skin research: Next Generation ImmunoDermatology

Research for better treatment methods for chronic skin diseases.

ERC Starting Grant awarded to Jeroen de Baaij

Jeroen de Baaij, kidney researcher the Radboudumc, receives an ERC Starting Grant worth 1.5 million euros. He will use this grant to improve the diagnosis and treatment of severe magnesium deficiencies, which can lead to epileptic seizures and muscle cramps.

Wanted: PhDs or postdocs to organize ENABLE symposium in Cologne in November 2023

Did you ever consider organising a scientific symposium? Do you want to improve your CV, collaborate with international PhD candidates, or get in touch with biomedical companies? We are now looking for the two representatives of Radboudumc.

Scan avoids unnecessary surgery for thyroid nodules PET scan with radioactive sugar is effective, cost-saving and safe

ERC Proof of Concept Grant for Martijn Verdoes

Martijn Verdoes, group leader Chemical Immunology at the department of Tumor Immunology, has been awarded an ERC Proof of Concept (PoC) Grant. The ERC PoC Grants are designed to support ERC grantees with the commercial or societal application of the results of their funded research.

Research on the development of kidneys in prematurely born children

Michiel Schreuder, together with Maastricht UMC+, is now starting a study into the kidneys of these children. For this, the researchers received a grant from the Kidney Foundation. 

Immunogenetic studies in diverse populations are essential Clear immunological differences between populations in Europe and Africa

Genetic factors that partly determine host defenses sometimes differ significantly between people and populations. This is shown in a publication in the American Journal of Human Genetics by researchers from the Netherlands, Tanzania and India.

Arnhem Nijmegen: top region in Health, High-Tech and Energy

Projects in the Arnhem Nijmegen region can expect millions of extra euros in the coming years. This will be used for, amongst other things, the circular economy and pioneering applications in the fields of Health, High-tech and Energy. 

Micro-Cosmos helps patient unwind during hospitalization

Nijmegen-based Micro-Cosmos is a start-up that makes retractable hoods to speed up the recovery of hospitalized patients.

LUMO Labs and Oost NL invest in Aiosyn Investment accelerates development of artificial intelligence platform to improve diagnostics

Aiosyn, a spin-off from Radboudumc, has received an investment from LUMO Labs. Oost NL is a co-investor.

Learning Social Dutch organized by RIMLS PhD council

Social Dutch is an initiative of the RIMLS PhD Council, aiming to bring together both Dutch and non-Dutch speaking colleagues. Dates to be announced.

What does the shingles vaccine teach us about other vaccines? Investigating the role of trained immunity

The vaccine for shingles, a condition that causes itching, pain, and blisters, is 90% effective, even in elderly. This is remarkable, since most vaccines offer less protection in elderly. Radboudumc is investigating why this vaccine works so well and how it might help us to develop better vaccines.

RIMLS PhD retreat 2022 Register now

This year, the 2-day RIMLS PhD retreat will be held on 14 & 15 July 2022 in the Koningshof, Veldhoven. We are aiming for a live event again!

Oncode collaboration: mobilizing innate leukocytes to attack tumors  Radboudumc is partner in a research project funded by KWF for 3.4 million euros

Laurens Verscheijden awarded doctorate degree 'cum laude'

Laurens Verscheijden of the Department of Pharmacology and Toxicology, defended his PhD thesis, entitled "Mechanistic models for the prediction of brain drug exposure and response in the paediatric population: A virtual child reaching maturation.

Looking back on RIMLS New Year celebration and awards

RIMLS organized a special online New Year Celebration, together looking back at the year 2021. René Bindels reviewed 2021 together with Clasien Oomen and Dagmar Eleveld-Trancikova, looked forward towards 2022 and presented the RIMLS awards and several other prizes.

Hans Jacobs receives KWF Proof-of-Concept grant to develop personalized cancer diagnostics

The Dutch Cancer Society (KWF) launched a new funding program to support successful KWF researchers to translate their results into clinical practice. Hans Jacobs and his team developed a personalized blood-test to measure minimal residual disease (MRD) in patients with multiple myeloma.

Radboud Postdoc Initiative (RPI) Pizza & Beer

On 2 February 2022 from 17:00 - 18:00 hrs the Radboud Postdoc Initiative will host an online meeting for Postdocs (and last year PhD candidates) with the theme ‘PhD to Start Up'. The meeting will be lead by Sruthi Sreekumar.

Scientists unite to shrink the carbon footprint in research "Flying thousands of miles for a 30 minute interview is very hard to justify during a climate crisis"

Novel high-resolution targeted sequencing of the cervicovaginal microbiome published in the Journal of BMC Biology

This project of William Melchers, Karolina Andralojc and Mariano Molina describe a novel sequencing method to profile the cervicovaginal microbiome at the species level and with the potential to elucidate the role of the microbiome in hrHPV-induced carcinogenesis.

Kidney damage as a result of coronavirus infection Coronavirus infects the kidneys and contributes to tissue scarring

What can we learn from rural Tanzanian food?

What we eat affects our bodies. A diet high in plant based products and low in fat offers health benefits and prevents lifestyle diseases, such as cardiovascular disease. This is what Quirijn de Mast shows based on his research in Africa.

Radboudumc receives 2.6 million Euro from KWF for cancer research

The Dutch Cancer Society (KWF) is awarding funds with a total of more than 2.6 million euros to five new research projects. The awards are part of the latest round of funding from KWF, in which almost 27 million euros is being allocated to Dutch cancer research. The projects will start in mid-2022.

NWO OTP grant to investigate fibrotic diseases with organ-on-a-chip technology

Wouter Verdurmen & Peter van der Kraan have been awarded with a grant by the Netherlands Organisation for Scientific Research (NWO-OTP) to develop and employ innovative organ-on-a-chip models to investigate fibrotic diseases, with a particular focus on systemic sclerosis.

Veni grants for RIMLS researchers

NWO has awarded 89 promising young scientists Veni funding of up to 280,000 euros. Three of them are from Radboud Institute of Molecular Life Sciences (RIMLS). They can develop their own research ideas over a period of three years.

New method improves diagnostics of lymphoma

Blanca Scheijen and Patricia Groenen of the Department of Pathology, together with a European consortium, developed a diagnostic method that more clearly distinguishes between inflammation and lymphoma in enlarged lymph nodes.