News items related to the Radboud Institute for Molecular Life Sciences.
High school science education program Immunology and Programming23 April 2019
International PhD candidates Joshua Gillard, Dorien Feyaerts and Yessica Rodriguez of the Laboratory of Medical Immunology (LMI), recently developed and implemented an exciting 4-day science challenge to teach vaccinology, immunology, and programming at the Lorenz Lyceum high school in Arnhem.
Interacting non-specific immunological effects of BCG and Tdapf vaccinations5 April 2019
In a randomized trial Mihai Netea and colleagues aim to investigate the non-specific immunological effects of BCG and DTP-containing vaccines on the immune response to unrelated pathogens. They have published their findings in Clinical Infectious Diseases.
Size matters: Miniaturised interaction proteomics with ultra-low input requirements4 April 2019
Cristina Furlan and René Dirks from the groups of Michiel Vermeulen and Hendrik Marks, theme Cancer development and immune defense, teamed up to develop a low-input interaction proteomics platform, called on-chip AP-MS. They published these findings in Nature Communications.
A personal touch of Glenn van Wigcheren4 April 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Glenn van Wigcheren.
Coronary angiography after cardiac arrest without ST-segment elevation2 April 2019
Niels van Royen, theme Vascular damage, found out and published in NEJM, that among patients who had been successfully resuscitated after out-of-hospital cardiac arrest and had no signs of STEMI, a strategy of immediate angiography was not found to be better than a strategy of delayed angiography.
Sarah Verhoeff wins audience award Radboud Talks Jury chose neuroscientist as overall winner26 March 2019
The winner of the fifth edition of scientific pitch competition Radboud Talks is Suhas Vijayakumar, PhD candidate at the Faculty of Social Sciences and the Donders Institute. Research physician Sarah Verhoeff, Radboud Institute for Health Sciences, won the audience award.
Biomaterials-aided mandibular reconstruction using in vivo bioreactors22 March 2019
In a collaborative effort, John Jansen en Jeroen van den Beucken, theme Reconstructive and regenerative medicine, have demonstrated in PNAS the feasibility of an in vivo bioreactor-based strategy to generate vascularized bony tissue and its use for mandibular reconstruction.
Grant to study mitochondrial morphofunction in Parkinson’s disease14 March 2019
Werner Koopman, theme Mitochondrial diseases, received 400,000 euro as a member of the PD-MitoQUANT consortium. The latter is an EU-funded Innovative Medicines Initiative research project that will improve our understanding of Parkinson’s so that better treatments can be developed in the future.
A personal touch of Georgina Flórez Grau10 March 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Georgina Flórez Grau.
15 million Euro to identify new drug targets for HIV28 February 2019
André van der Ven and Mihai Netea, theme Infectious diseases and global health, and colleagues, will receive 15 million Euro from pharmaceutical company ViiV Healthcare for research into new ways to fight the HIV virus. The aim of the HIV 2000+ project is to identify new drug targets for HIV.
Valentine’s day spectacle at the Radboud Research Rounds21 February 2019
This year’s Valentine’s day in the Radboudumc was focused on the RRR of the Tumors of the Digestive Tract. In the biannual Paper Award session the big prize went to Daniel Garza from the Center for Molecular and Biomolecular Informatics, for his paper on “the environmental metabolome”.
Imprinted genes during early embryonic development18 February 2019
René Dirks, with other members from the lab of Hendrik Marks, theme Cancer development and immune defense, show in a paper in Epigenetics & Chromatin that genomic imprinting (genes expressed from the paternal or maternal allele only) is often lost in cultured embryonic stem cells.
The first Radboud Nanomedicine community networking event14 February 2019
On 7 February 2019 the first Radboud Nanomedicine community networking event took place. The goal of the event was to bring together all those working in the field of nanomedicine at the Radboud University and Radboudumc, irrespective of the theme in which the research is performed.
Research Integrity Round: The ConScience App 15 February 201914 February 2019
To introduce the new Netherlands Code of Conduct for Research Integrity we invited ‘Het Acteursgenootschap’ to perform ‘The ConScience App’, a theatre piece designed to move the debate on scientific knowledge. All Radboudumc researchers are invited to attend this event.
Gene involved in colorectal cancer also causes breast cancer14 February 2019
Judith Grolleman, Nicoline Hoogerbrugge and Richarda de Voer, theme Tumors of the digestive tract, published in Cancer Cell that mutations in the NTHL1 gene, previously associated with colorectal cancer, also cause breast cancer and other types of cancer.
Endometrial natural killer cells remember previous pregnancy11 February 2019
Dorien Feyaerts, theme Inflammatory diseases, showed that pregnancy induces a memory phenotype on endometrial natural killer cells. However, previous CMV infection is a prerequisite for this memory induction. They published their findings in Cellular and Molecular Immunology.