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About
GLOBAL-DATA-MATCH is an international, world-leading collaboration between Radboudumc, University of Glasgow and Liverpool John Moores University, aiming to provide definitive estimates on the effect of exercise-based cardiac rehabilitation in people with cardiovascular disease.
Secondary prevention strategies through the application of exercise-based cardiac rehabilitation (ExCR) are recognized by international guidelines as an integral component of contemporary management of various cardiovascular diseases, including coronary heart disease (CHD), heart failure (HF) and atrial fibrillation (AF). To provide definitive estimates of the effect of ExCR and inform future guidelines on ExCR prescription, GLOBAL-DATA-MATCH aims to bring together individual participant data from randomized controlled trials on the effectiveness of ExCR versus usual care.
GLOBAL-DATA-MATCH includes a collection of “living” individual participant data meta-analyses, and brings together individual participant data from randomized trials on the effectiveness of ExCR in CHD (CaReMATCH), AF (AFterMATCH) and HF (ExTrMATCH).
As of March 2025, 27 trials, including approximately 9,000 participants, have been included in our analyses. GLOBAL-DATA-MATCH is constantly updated with information from "living" Cochrane reviews on ExCR in CHD, AF, and HF, which are co-led by the principal investigators of GLOBAL-DATA-MATCH. Publications of GLOBAL-DATA-MATCH have been published in leading journals, including the European Heart Journal of Heart Failure, BMJ, and JACC. We also collaborate with patient and public involvement groups across the globe (Harteraad, the Netherlands; REACH-HF patient-participation group, Arrythmia Alliance, UK; StopAfib, US).
Participation
We invite principal investigators of randomized controlled trials on ExCR to share their individual participant data and participate in GLOBAL-DATA-MATCH. Data security and transparency are key priorities, and participation follows clear guidelines and ethical standards. If you’re interested in learning more, we welcome you to get in touch (see "Contact").
Team
GLOBAL-DATA-MATCH is led by:
- Prof. Rod Taylor - Professor of Population Health Research, University of Glasgow
- Dr. Ben Buckley - Senior lecturer, Liverpool John Moores University
- Prof. Dick Thijssen - Professor of Cardiovascular Physiology, Radboudumc
Other team members are:
- Drs. Niels Stens - PhD candidate and epidemiologist, Radboudumc
- Dr. Grace Dibben-Santillan - Research associate, University of Glasgow
- Dr. Geert Kleinnibbelink - Cardiologist in training, Radboudumc
- Dr. Laurien Buffart - Associate professor and epidemiologist, Radboudumc
