NL
DE
5 April 2019
Outline of this thesis
In chapter 2 we assessed the habitual protein intake of physically active older adults and the prevalence of the population that met the protein intake guidelines. This is important as sufficient protein intake is needed to utilize the benefits of the exercise-induced enhanced muscle protein synthesis and, thus, to prevent age-related muscle mass loss.
The beneficial effect of enhancing protein intake with supplementation has shown conflicting results, which may partly be explained by the different target groups. Whereas in frail older adults often promising results are found, in non-frail community-dwelling older adults more conflicting results are present. In chapter 3 we performed a meta-analysis on exclusively non-frail community-dwelling older adults to assess the effect of protein supplementation on lean body mass, muscle strength and physical performance. Moreover, we assessed the superior effects of protein supplementation during resistance exercise training on muscle characteristics in exclusively non-frail community-dwelling older adults.
Habitual protein intake, protein distribution and physical activity levels of participants can also affect muscle characteristics. In chapter 4 we investigated whether protein intake and protein intake distribution are associated with muscle strength, physical function and quality of life in community-dwelling older adults while additionally accounting for the role of physical activity.
In chapter 5 we assessed the effects of 12 weeks of daily protein supplementation on lean body mass, muscle strength and physical performance in physically active older adults with a low habitual protein intake using a randomized double-blinded controlled trial.
In chapter 6 we assessed another contributing factor for optimal muscle health, vitamin D. We assessed the vitamin D status in different age subgroups of physically active older adults. Moreover, we assessed which determinants contributed to vitamin D status.
Finally, in chapter 7 we discuss the concepts of each chapter and how they related to each other, we describe how they support the current body of literature and discuss the most important findings and implications and provide future directions for research in this area.
Click here to access Dominique' thesis digitally.
Dominique ten Haaf obtained her PhD degree in the Medical Sciences of the Radboud University Nijmegen after the successful defense of her thesis.
Outline of this thesis
In chapter 2 we assessed the habitual protein intake of physically active older adults and the prevalence of the population that met the protein intake guidelines. This is important as sufficient protein intake is needed to utilize the benefits of the exercise-induced enhanced muscle protein synthesis and, thus, to prevent age-related muscle mass loss.
The beneficial effect of enhancing protein intake with supplementation has shown conflicting results, which may partly be explained by the different target groups. Whereas in frail older adults often promising results are found, in non-frail community-dwelling older adults more conflicting results are present. In chapter 3 we performed a meta-analysis on exclusively non-frail community-dwelling older adults to assess the effect of protein supplementation on lean body mass, muscle strength and physical performance. Moreover, we assessed the superior effects of protein supplementation during resistance exercise training on muscle characteristics in exclusively non-frail community-dwelling older adults.
Habitual protein intake, protein distribution and physical activity levels of participants can also affect muscle characteristics. In chapter 4 we investigated whether protein intake and protein intake distribution are associated with muscle strength, physical function and quality of life in community-dwelling older adults while additionally accounting for the role of physical activity.
In chapter 5 we assessed the effects of 12 weeks of daily protein supplementation on lean body mass, muscle strength and physical performance in physically active older adults with a low habitual protein intake using a randomized double-blinded controlled trial.
In chapter 6 we assessed another contributing factor for optimal muscle health, vitamin D. We assessed the vitamin D status in different age subgroups of physically active older adults. Moreover, we assessed which determinants contributed to vitamin D status.
Finally, in chapter 7 we discuss the concepts of each chapter and how they related to each other, we describe how they support the current body of literature and discuss the most important findings and implications and provide future directions for research in this area.
Click here to access Dominique' thesis digitally.
