advice and support

Qualified and competent

get certified
register
access to CDL
get iVentionLES account

Project license

apply

Protocol

write protocol
schedule planning meeting
request for animal products
surplus animals

Amendment

amendment

Closure

evaluate

advice and support

Process of animal experimentation

This timeline offers a guide to the process of animal experimentation to staff of Radboud University or Radboudumc. If you have any questions or need further assistance, please feel free to contact us.

Animal Welfare Body

The AWB acts on behalf of the Radboud University to oversee legal supervision of the performance of animal experiments and the welfare of laboratory animals, in accordance with the Animal Experimentation Act. The AWB is available via email and several contact persons.

read more

Animal Welfare Body

The Animal Welfare Body (AWB) (Instantie voor Dierenwelzijn IvD) helps to ensure a responsible animal experimentation policy within Radboud University and Radboudumc. The AWB acts on behalf of  the Radboud University to oversee legal supervision of the performance of animal experiments and the welfare of laboratory animals, in accordance with the Animal Experimentation Act.

Organizationally, the AWB falls under the Animal Research Facility (CDL). The AWB is composed of animal welfare officers, bio-technicians, and one or more scientists. If necessary, the group is supplemented by a veterinarian, statistician, or other specialists.

Additional information can be found below the contact information.

Contact

Email
instantievoordierenwelzijn@radboudumc.nl
Secretary AWB
Janny Verstegen-Gröning
Contact persons
Pieter Verbost: +31 (0)24 309 23 69
Roel Sneepers: +31 (0)24 309 23 68
Miriam Kool: +31 (0)24 309 23 64
Adriana Silveira de Souza (Tu. & Th.): +31 (0) 6 37408930

Additional information

Any institution that performs experiments on animals, or breeds or supplies animals for experiments, is required by the provisions of the 'Wet op de dierproeven' to set up such a body. We conduct our TASKS primarily for Radboud University and Radboudumc, and also for a few other educational and research institutions.

Optimal welfare for animals 
Our goal is to ensure that the optimal welfare of laboratory animals is an integral part of the structure of the Radboud University and Radboudumc. Of key importance is the optimal use of alternatives and proper and responsible research within the legal frameworks and with extra attention paid to replacement, reduction and refinement (3Rs).

Collaboration at all levels
In order to achieve these goals, we work closely together with researchers, research technicians, animal caretakers, managers and directors of Radboud University and Radboudumc. Together we maintain a ‘culture of care’.

Tasks
The Animal Welfare Body has a large number of tasks that we conduct on behalf of Radboud University and Radboudumc. These tasks are largely prescribed by law in accordance with the provisions of the Experiments on Animals Act. These tasks deal with issues such as animal welfare, alternatives to animal experiments, procedures, registration, supervision and communication with the Central Authority for Scientific Procedures on Animals (CCD). The most important of these tasks include:
Animal welfare and alternatives
  • offering advice on animal welfare during acquisition, accommodation, care and utilisation of animals
  • offering advice on replacement, reduction and refinement (3Rs)
  • providing information about technical and scientific developments
  • establishing and testing procedures for monitoring and reporting on animal welfare
  • providing information and advice on the rehousing scheme and the appropriate socialisation of the animals
Procedures
  • discussing a project proposal with the applicant prior to applying for a project licence from the Central Authority for Scientific Procedures on Animals (CCD)
  • consulting with the researcher prior to the conduct of an animal experiment
  • working with the researcher to determine whether changes in the project must be submitted to the CCD
Registration and supervision
  • collecting registration data on animals and experiments
  • monitoring the welfare of laboratory animals
  • supervising the registration and evaluation of authorizations, expertise and skills of those working with laboratory animals
Central Authority for Scientific Procedures on Animals (CCD)
  • providing information for retrospective evaluation
  • reporting cases when a project is conducted differently than specified in the licence
  • reviewing the non-technical summary
  • all other correspondence with the CCD
And more…
  • developing internal policy
  • communicating about animal experiments (policy)
  • contributing to training and education
  • acting as the first point of contact in the event of problems or potential problems pertaining to animal welfare 
  • encourage cooperation and collaboration between researchers and animal caretakers
  • acting as the first point of contact for inspectors from the Netherlands Food and Consumer Product Safety Authority (NVWA)

Contact

  • The Animal Welfare Body (AWB) is available via e-mail and several contact persons.

    read more


    Content related help

    Email
    instantievoordierenwelzijn@radboudumc.nl

    Secretary AWB
    Janny Verstegen-Gröning

    Contact persons
    Pieter Verbost: +31 (0)24 309 23 69
    Roel Sneepers: +31 (0)24 309 23 68
    Miriam Kool: +31 (0)24 309 23 64

  • Proces related help

    Helpdesk
    Email: helpdesk.cdl@radboudumc.nl
    T: +31 (0)24 361 35 00

    Contact persons
    Dorien van de Pol: +31 (0)24 361 93 80            
    Christien Frederiks: +31 (0)24 36 13500

Codes of Practice

The University Utrecht has an overview of Codes of Practice, guidelines and tools. visit website

Technology center Animal Research Facility

This timeline is part of Radboudumc's Animal Research Facility. go to facility

Qualified and competentget certified


Certification

The law requires that those involved in experiments on animals must be qualified. The successful candidate of the LAS course will get a FELASA accredited certificate.

read more

Certification

The law requires that those involved in experiments on animals must be qualified. The successful candidate of the LAS course will get a FELASA accredited certificate of the Radboud University and will be registered in the European FELASA database.

The LAS course has been accredited by the Federation of European Laboratory Animal Science Associations (FELASA). FELASA represents common interests in the furtherance of all aspects of laboratory animal science (LAS) in Europe and beyond. The FELASA accreditation program follows the requirements stated in article 23 of the EU Directive 2010/63  and the EC Guidelines (European Commission, 2014) and is recognized as the premier accreditation scheme in Europe for LAS courses.

Laboratory Animal Science course (LAS) art. 9

This course is designed to train participants in accordance with the requirements of Article 9 of the Experiments on Animals Act. The course includes all relevant topics related to the design of ethically, legally and scientifically appropriate animal experiments. read more

Need more info? Contact us

Merel Ritskes-Hoitinga PhD
LAS course coordinator

contact

register


Registration of persons involved in animal experiments

The law requires that those involved in experiments on animals must be registered at the Animal Welfare Body.

access to CDL


Under construction

Content for this step will follow soon.

get iVentionLES account


iVentionLES

iVentionLES is the laboratory execution system for animal experimentation. It supports the entire cycle of a research project: from the research question involving animal experiments to the implementation of these experiments and the registration of the research results.

read more

iVentionLES

iVentionLES is the laboratory execution system (LES) for animal experimentation used at Radboudumc and Radboud University. The system supports the entire cycle of a research project: from the research question involving animal experiments to the implementation of these experiments and the registration of the research results. In addition, financial data, invoicing information and management data is generated as output.
 
iVentionLES is a modular system. Each module is released separately.

Authorization

Every researcher registered at the Animal Welfare Body of the Radboudumc can get access to iVentionLES. Please send the request for an account to the helpdesk of the Radboud Animal Research Facility (in Dutch: Centrale Dierenlab).

Log in

> go to log in IVentionLES

Contact

Helpdesk
Email: helpdesk.cdl@radboudumc.nl
T: +31 (0)24 361 35 00
Contact persons
Dorien van de Pol: +31 (0)24 361 93 80            
Christien Frederiks: +31 (0)24 36 13500

Ask for an account

All persons registered at the Animal Welfare Body of Nijmegen can ask for an iVentionLES account. Please send the request for an account to the helpdesk of the Radboud Animal Research Facility

Contact The iVentionLES team

The team is available via email and several contact persons.

read more

Contact The iVentionLES team

Helpdesk
Email: helpdesk.cdl@radboudumc.nl
T: +31 (0)24 361 35 00
Contact persons
Dorien van de Pol: +31 (0)24 361 93 80            
Christien Frederiks: +31 (0)24 36 13500

Project licenseapply


Applying for a project licence

Researchers who wish to begin a research or education project that involves experiments on animals are required to apply for a licence from the Central Authority for Scientific Procedures on Animals (CCD).

Elements

The application for a project licence consists of

  • the project proposal
  • a non-technical summary (NTS)
  • the description of animal procedures

Advice

The Animal Welfare Body offers advice and support during the entire process of drafting and writing of a project in iVentionLES and applying for the project licence at the Central Authority for Scientific Procedures on Animals (CCD). The AWB is available via email and several contact persons.

read more

Advice

The Animal Welfare Body offers advice and support during the entire process of drafting and writing of a project in iVentionLES and applying for the project licence at the Central Authority for Scientific Procedures on Animals (CCD).

Contact

Email
instantievoordierenwelzijn@radboudumc.nl
Secretary AWB
Janny Verstegen-Gröning
Contact persons
Pieter Verbost (Mo., Tu. & We.): +31 (0)24 309 23 69
Roel Sneepers (Th. & Fr.): +31 (0)24 309 23 68
Miriam Kool (Mo., Tu. & Th.): +31 (0)24 309 23 64
 

 


Process flow

View the summary regarding the project application.

read more

Process flow


Application forms

All forms are available in iVentionLES. log in at iVentionLES

Protocolwrite protocol


Procedure forms

The protocol describes the details of an animal experiment and the actions to be taken by those performing an animal experiment. The protocol form and information on the procedure is available in iVentionLES. log in at iVentionLES

Process flow

View the summary for the protocol submission.

see image

Process flow

schedule planning meeting


Start-up meeting

After approval of the protocol by the Animal Welfare Body, a meeting with the Animal Research Facility contact person(s) needs to be scheduled. This is to discuss and plan the details of the execution of the experiment (who does what).

Teams and contact information

Animal Research Facility has four teams.

request for animal products


Use of animal products and biological material

To receive biological materials from surplus animals please get in touch with your CDL contact person. Click 'read more' for information about the definition for biological material. If you have any questions please contact the AWB (contact information available in block 'Animal Welfare Body').

read more

Use of animal products and biological material

To use biological materials from animals culled in the context of an experiment or from culled surplus breeding animals, it is no longer needed to fill in a biological materials form. To receive biological materials from surplus animals please get in touch with your CDL contact person.
 
It is strictly forbidden to specifically breed or house any animals for the purpose of acquiring biological materials, without a valid project license and protocol. Likewise, perfusions or other terminal procedures under anaesthesia are not allowed in the context of biological materials. For these procedures a valid project license and protocol is mandatory.
 
The CDL will decide when animals are surplus and at what time they will be culled. Animals will always be killed using standard procedures (CO2 or Cervical dislocation).

Animal Welfare Body

The AWB acts on behalf of the Radboud University to oversee legal supervision of the performance of animal experiments and the welfare of laboratory animals, in accordance with the Animal Experimentation Act. The AWB is available via email and several contact persons.

read more

Animal Welfare Body

The Animal Welfare Body (AWB) (Instantie voor Dierenwelzijn IvD) helps to ensure a responsible animal experimentation policy within Radboud University and Radboudumc. The AWB acts on behalf of  the Radboud University to oversee legal supervision of the performance of animal experiments and the welfare of laboratory animals, in accordance with the Animal Experimentation Act.

Organizationally, the AWB falls under the Animal Research Facility (CDL). The AWB is composed of animal welfare officers, bio-technicians, and one or more scientists. If necessary, the group is supplemented by a veterinarian, statistician, or other specialists.

Additional information can be found below the contact information.

Contact

Email
instantievoordierenwelzijn@radboudumc.nl
Secretary AWB
Janny Verstegen-Gröning
Contact persons
Pieter Verbost: +31 (0)24 309 23 69
Roel Sneepers: +31 (0)24 309 23 68
Miriam Kool: +31 (0)24 309 23 64
Adriana Silveira de Souza (Tu. & Th.): +31 (0) 6 37408930

Additional information

Any institution that performs experiments on animals, or breeds or supplies animals for experiments, is required by the provisions of the 'Wet op de dierproeven' to set up such a body. We conduct our TASKS primarily for Radboud University and Radboudumc, and also for a few other educational and research institutions.

Optimal welfare for animals 
Our goal is to ensure that the optimal welfare of laboratory animals is an integral part of the structure of the Radboud University and Radboudumc. Of key importance is the optimal use of alternatives and proper and responsible research within the legal frameworks and with extra attention paid to replacement, reduction and refinement (3Rs).

Collaboration at all levels
In order to achieve these goals, we work closely together with researchers, research technicians, animal caretakers, managers and directors of Radboud University and Radboudumc. Together we maintain a ‘culture of care’.

Tasks
The Animal Welfare Body has a large number of tasks that we conduct on behalf of Radboud University and Radboudumc. These tasks are largely prescribed by law in accordance with the provisions of the Experiments on Animals Act. These tasks deal with issues such as animal welfare, alternatives to animal experiments, procedures, registration, supervision and communication with the Central Authority for Scientific Procedures on Animals (CCD). The most important of these tasks include:
Animal welfare and alternatives
  • offering advice on animal welfare during acquisition, accommodation, care and utilisation of animals
  • offering advice on replacement, reduction and refinement (3Rs)
  • providing information about technical and scientific developments
  • establishing and testing procedures for monitoring and reporting on animal welfare
  • providing information and advice on the rehousing scheme and the appropriate socialisation of the animals
Procedures
  • discussing a project proposal with the applicant prior to applying for a project licence from the Central Authority for Scientific Procedures on Animals (CCD)
  • consulting with the researcher prior to the conduct of an animal experiment
  • working with the researcher to determine whether changes in the project must be submitted to the CCD
Registration and supervision
  • collecting registration data on animals and experiments
  • monitoring the welfare of laboratory animals
  • supervising the registration and evaluation of authorizations, expertise and skills of those working with laboratory animals
Central Authority for Scientific Procedures on Animals (CCD)
  • providing information for retrospective evaluation
  • reporting cases when a project is conducted differently than specified in the licence
  • reviewing the non-technical summary
  • all other correspondence with the CCD
And more…
  • developing internal policy
  • communicating about animal experiments (policy)
  • contributing to training and education
  • acting as the first point of contact in the event of problems or potential problems pertaining to animal welfare 
  • encourage cooperation and collaboration between researchers and animal caretakers
  • acting as the first point of contact for inspectors from the Netherlands Food and Consumer Product Safety Authority (NVWA)

Teams and contact information

Animal Research Facility has four teams.

surplus animals

Amendmentamendment


Process flow

View the summary regarding the amendments.

see image

Process flow

Closure evaluate


Evaluation form

Email form to instantievoordierenwelzijn @radboudumc.nl. download form

Procedure after the study

If you have completed an animal experiment or a series of animal experiments, your work is not yet done.

read more

Procedure after the study

If you have completed an animal experiment or a series of animal experiments, your work is not yet done.

Welfare Evaluation

After finishing each Work Protocol, you, being the researcher, fill out a Welfare Evaluation and send it to your CDL contact person for confirmation. Then, send it to instantievoordierenwelzijn@radboudumc.nl. The act of evaluating the experiment and capturing the information in the welfare evaluation document will both help you and your colleagues to estimate the discomfort level of future experiments and to be alert to welfare issues. 

ARRIVE

You may be working on a publication. To make animal experiments understandable for others on a detailed level, it is best to use the ARRIVE-guidelines when writing your article. 

Statement

Do you need a statement for your article, stating that the animal experiments have been issued a licence and were conducted in accordance with legal standards, then we can provide it. Let us know (instantievoordierenwelzijn@radboudumc.nl

Publication bias

To prevent publication bias, it is important that you make any results public, even if they are disappointing. Even if your experiment has failed, others can learn from your description of what went wrong, which will prevent them from making the same mistake. This is important in any research, but even more in animal experiments. If you haven't registered your research yet on www.preclinicaltrials.eu, you can still do so.

Technology center Animal Research Facility

This timeline is part of Radboudumc's Animal Research Facility. go to facility