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Goals

  • To advance mechanistic understanding of how stress affects brain structure and function by integrating insights across levels from molecules to neurocognitive system and behavior and across animal and human experimental models. 
  • To identify genetic and environmental factors that confer risk and resilience to stress, and to uncover the transdiagnostic disease and resilience mechanisms that operate across timescales – from immediate responses to life episodes and across the lifespan. 
  • To develop individualized and targeted interventions for the treatment and prevention of transdiagnostic stress-related symptoms or the mitigation of somatic disease symptoms, based on mechanistic, genetic, developmental, and computational understanding. 
  • To advance analytical data science approaches for investigating quantitative (bio)markers (including neuroimaging, -omics, population registries, satellite remote sensing, and offline as well as real-time behavioral/digital phenotyping) for stress responsiveness and resilience, including the development of new algorithms. 


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Research Research programs Stress and mental health

Our mission

We aim to tackle one of the greatest public health challenges of our time: decreasing the vast burden of stress-related mental health problems, both in psychiatric and somatic illnesses.

Goals

See some of the most important goals for this research program.

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Research groups contributing to this research program

Addiction psychiatry

Arnt Schellekens's research group aims to reduce the tremendous burden of addictive disorders through translational research, linking basic science with clinical practice. The group focuses on disentangling clinical heterogeneity, in order to develop personalized addiction treatment strategies.

Behavioural neuroscience

Benno Roozendaal's research group investigates the effects of stress and emotional arousal on learning and memory.

Clinical neuroscience in psychiatry

Indira Tendolkar's research group works on understanding how individuals adapt to stress in both health and psychiatric conditions.

Spokesperson(s) for this research program

Spokeperson

dr. Martine Hoogman

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Spokeperson

dr. Marloes Henckens

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Spokesperson

prof. dr. Erno Hermans

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