7 November 2018

Yonne Peters and Peter Siersema obtained a MLDS grant of €250k for their project ‘Early detection of Barrett’s esophagus and esophageal cancer: accuracy and acceptability of a novel screening strategy in primary care’.

By 2030, 1 in 100 men in the Netherlands are predicted to be diagnosed with esophageal cancer during their lifetime. This large increase in incidence and the dismal prognosis of this tumor have stimulated interest the early detection of its precursor Barrett’s esophagus.The aim of the project is to determine the accuracy and acceptability of a non-invasive screening strategy (breath analysis with an electronic nose) followed by unsedated transnasal endoscopy (TNE)) for detecting Barrett’s esophagus and esophageal cancer in a primary care setting.Their ultimate goal is to implement breath test technology as a screening test in standard primary care for patients with (long-term) reflux symptoms. This may lead to an earlier detection of esophageal cancer, less invasive treatment, better survival rates, and even to the prevention of esophageal cancer.

This research was conducted within the theme: Tumors of the digestive tract

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