7 November 2018

On 1 November 2018, the Radboudumc New Frontiers symposium about the way big data changes healthcare, took place in front of an audience of about 300 scientists.

The symposium was chaired by René Melis. The complete program can be found here.

With new scientific insights and increasing technological possibilities medical research is rapidly changing. Increased computer capacity, availability of data and connectivity between databases have propelled the development of fields such as multi-omics, network medicine and computational medicine. Insights derived from the application of these new methodologies change the way we look at diseases: what once was one disease increasingly turns out to be a collection of rare entities with their own etiology, diagnosis and treatment. Vice versa, we begin to understand how health and disease are inherently multiscale phenomena that emerge out of complex and dynamic interactions within and between a person and his environment. Technologies like lab on a chip and self monitoring with all kinds of sensors change the way we collect data to make a diagnosis and the way we monitor diseases. At the same time, healthcare has seen a strong fragmentation leading to a more complex healthcare delivery and organization.
During the symposium a peek was provided into the promise and challenges of big data application to healthcare.
Examples from the application of deep learning to image reading in pathology and radiology and the application of network medicine to monitor infectious disease outbreaks or collective mood states using twitter data showed the huge potential of big data approaches for building a better (public) healthcare. If we invest in carefully opening up the data sources such as electronic health records through for example natural language programming, high quality data are available for healthcare data science. Several challenges still remain. For example when to apply which methodology and the ethical and legal repercussions of healthcare data science. This requires that experts from different disciplines team up for the best result.

John Graunt award
Alessandro Vespignani received the John Graunt Award 2018, in recognition of his ground breaking research in the spreading of lethal infectious diseases.
John Graunt is considered as one of the first demographers and epidemiologists. An award in his name serves to honour the recipients for their eminence and influence in the health sciences.
Professor Vespignani’s research activities focus on the data-driven computational modeling of epidemic and spreading phenomena and the study of biological, social and technological networks. With his work, he contributed to health protection of people around the planet by combining two research fields: epidemiology and network science. He showed that the social network of people plays a major role in the spreading of viruses. And this forms the basis for health scientists who are building models for the prediction and prevention of the spreading of viruses such as Zika and Ebola.
     
Laptop presentation award
During the lunch PhD candidates and postdocs presented their research via laptop presentations. An excellent jury reviewed the presentations. The winner of the Laptop presentation award was Ankie Suntjens with her presentation ‘Text mining in electronic patient records for the early identification of the palliative phase’.

Here you can view all the pictures (made by Rob Gieling).

Past symposia
Every year, RIMLS and RIHS each organize an international symposium across one of the thematic areas of the Radboudumc with the intention of exploring the newest scientific research and pioneering developments from molecule to man and population. Here you can find more information about the past symposia.
 

Related news items


Optimal dosing of anti-HIV drug darunavir in pregnant women

21 February 2019

In the Journal of Antimicrobial Chemotherapy Stein Schalkwijk, Rob ter Heine, Angela Colbers and David Burger investigated how pregnant women should be treated with the anti-HIV drug darunavir.

read more

Celebrations to mark the retirement of Joost Schalkwijk

21 February 2019

With a mini symposium (‘Oppervlakkig en toch diepgaand’) and reception a passionate researcher of the RIMLS said farewell. After 36 working years Joost Schalkwijk, theme Inflammatory diseases, will enjoy his retirement.

read more

Ultrahigh-resolution MRI reveals structural brain differences in serotonin transporter knockout rats after sucrose and cocaine self-administration

20 February 2019

In Addiction Biology Peter Karel and Judith Homberg showed that rats lacking the serotonin transporter show increased cocaine, but unaltered sucrose, self-administration.

read more

RIHS awardees 2017 and 2018 Koek & Zopie ceremony

20 February 2019

During this event RIHS awardees accepted their awards for the best PhD thesis, the research product with the highest impact on society, the best peer-reviewed publication, and the Supervisor of the year.

read more

Standing balance capacity is easily overestimated in well-recovered stroke survivors

20 February 2019

In Neurorehabilitation and Neural Repair Jolanda Roelofs and Sander Geurts showed that well-recovered persons in the chronic phase after stroke with clinically no (or only very limited) motor impairment of the affected leg may still show substantial problems with standing balance control.

read more

Imprinted genes during early embryonic development

18 February 2019

René Dirks, with other members from the lab of Hendrik Marks, theme Cancer development and immune defense, show in a paper in Epigenetics & Chromatin that genomic imprinting (genes expressed from the paternal or maternal allele only) is often lost in cultured embryonic stem cells.

read more