29 April 2019

Transradial intervention (TRI) may impair digital perfusion with hand dysfunction as a result. However, the effect of TRI on digital perfusion has never been investigated, including the influence of variations of the collateral arterial network and the effect on hand dysfunction.

Niels van Royen, theme Vascular damage, and colleagues, investigated the effect of TRI on digital perfusion by laser doppler perfusion imaging. They concluded in Circulation: Cardiovascular Interventions, that TRI is safe. Digital perfusion is reduced in both hands during radial access and TR band application but is not associated with future loss of hand function and variations of the arterial hand supply.

Laser Doppler perfusion imaging was performed at baseline, during radial access, TR band application, and at discharge. compared tissue perfusion of the homolateral thumb (access site) with the contralateral thumb (comparator) during radial access as primary outcome. The hand circulation was assessed with angiography. Upper extremity function was evaluated with the validated QuickDASH questionnaire at baseline and follow-up. A significant reduction of tissue perfusion was observed during radial access and TR band application in the homolateral thumb (−32%, −32%, respectively) and contralateral thumb (−34%, −21%, respectively). They detected no perfusion difference between the homolateral and contralateral thumb during radial access (217; interquartile range, 112–364 versus 209; interquartile range, 99–369 arbitrary flux units; P=0.59). Reduced perfusion of the thumb during radial access was not associated with incompleteness of the superficial palmar arch (P=0.13). Digital perfusion improved at discharge, though it remained below baseline levels (homolateral −11% and contralateral −14%). Hand dysfunction at 18 months was not associated with TRI-induced perfusion reduction (P=0.54).

Related news items

European Commission Initiative on Breast Cancer (ECIBC) Guidelines

13 August 2019

In Annals of internal medicine Mireille Broeders and colleagues from the ECIBC Guidelines Development Group described the methods used to develop person-centered evidence-based recommendations for screening and diagnosis of breast cancer.

read more

Circulation publication for exercise physiologists

13 August 2019

Thijs Eijsvogels and Vincent Aengevaeren showed that exercise-incuded elevations of troponin concentrations are predictive of major adverse cardiovascular events and mortality.

read more

DELA, Radboudumc and Games for Health start a new project to fight loneliness among elderly using games

12 August 2019

More than half of people aged 75 and over feel their selves lonely every now and then. A special collaboration between DELA, Radboudumc, and Games for Health will investigate whether joined gaming between elderly and young people can alleviate this social problem.

read more

Floris Schreuder received Dekker grant

6 August 2019

Floris Schreuder received one of the ten Dekker grants from the Dutch Heart Foundation (Hartstichting).

read more

A warm welcome for a new RIMLS colleague Nico Sommerdijk

5 August 2019

As of 1 August we welcome Nico Sommerdijk as our new colleague at the RIMLS. Nico will join the department of Biochemistry, with his research group “Biochemistry of Mineralized Tissues”.

read more

Bart Kiemeney finishes 1st in the Tour and raises thousands of euros

30 July 2019

With over €43,000 on the counter, Kiemeney can see the Tour de France as a great success.

read more