Johannes Textor, theme Cancer development and immune defense, has been awarded a program grant of 1 million US dollars by The Human Frontier Science Program (HFSP), together with his team members Judith Mandl (McGill University, Montreal, Canada) and Daniel Parisi (Buenos Aires institute of Technology, Argentina).
The T cells of the adaptive immune system are constantly on the move, can enter most tissues, and operate inlarge crowds. Millions of densely packed T cells roam the lymphatic organs in search of foreign antigen while activated T cells divide vigorously and flock to tissues where they mount local immune responses to pathogens or cancer cells.
The HFSP project combines expertise in immunology, computational biology, and pedestrian dynamics to shed light how T cell crowds remain motile with such remarkable efficiency in many conditions and what it would take to disrupt their smooth flow
HFSP grants are highly competitive awards intended for basic research at the frontier of human knowledge. They are open to applicants from all nations, and awardees are selected through a rigorous year-long review process. From more than 700 proposals that were initially submitted by scientists based in more than 50 different countries, only the top 4% were funded, and Johannes Textor's propasal was ranked third overall. Johannes Textor was the only scientist from a Dutch instutition to be selected.
Related news items
New research through grants for Radboudumc researchers14 January 2021
Several researchers at the Radboudumc have received grants to start new studies, including on rare diseases, liver disease and cancer metastases. These are grants from the Dutch Research Council, European Joint Programme on Rare Diseases and the Gastric Liver Disease Foundation.read more
Should we prepare for a corona-related depression wave? Indira Tendolkar and Eric Ruhé talk about their research projects13 January 2021
Since the outbreak of the SARS-CoV-2, many of us have been staying at home in order to limit our social interactions, to keep ourselves and others safe from the virus. Yet, there’s also concern about what social distancing and anxiety generated by media reports are doing to people's mental health.read more
RIMLS online award ceremony proudly presenting the winners13 January 2021
In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony.read more
Cooling vests alleviate perceptual heat strain perceived by COVID-19 nurses11 January 2021
Wearing cooling vests during a COVID-19 shift ensures that nurses experience less heat during their work. The cooling vests offer such effective cooling that they are now part of the standard work clothing for nurses in the COVID nursing departments at Radboudumc.read more
Koen van den Dries received ENW-XS grant from the NWO7 January 2021
Koen van den Dries has received an ENW-XS grant from the NWO for his project titled: Small differences, large impact: how actin variants differentially control cancer cell migration.read more