We focus on basic and translational research in the medical biosciences, from molecules to humans, to better understand disease and health and improve diagnostics and treatment.
We combine research and teaching in various aspects of Medical Biosciences from the molecular to the whole body level.
We study the biochemical, cellular and physiological aspects of biological processes in health and disease, using both experimental and informatics approaches, and to use this knowledge to further improve health care.
We work on the development of new drug delivery approaches, biomaterials for tissue engineering, and the immunological treatment of tumors, aiming at the translation of our findings to clinical applications.
Dendritic Cell (DC) therapy represents a promising immunotherapeutic approach for the treatment of cancer.
The beauty of DC therapy is that it exploits the body's own immune system to fight cancer. Since 1997 we perform clinical trials to test the potency of this approach. For each patient a specialized vaccine is prepared from immune cells isolated from the blood. In specialized cleanrooms, a personalized DC vaccine is prepared after which patients are vaccinated.
So far, our clinical trials are mainly focused on melanoma, a cancer of the pigmented cells of the skin. We have treated more than 350 patients until now and observed that DC vaccination is well tolerated with minimal side effects.
More information can be found on the website of Stichting Afweer Tegen Kanker.
Merging of departments
This department is a merger of the 5 departments Biochemistry, Cell Biology, CMBI (Center for Molecular and Biomolecular Informatics), Physiology, and Tumor Immunology.
Our technology centers
Technology center Bioinformatics
This technology center offers computational biology and big data solutions that we believe are key in shaping the data-driven life science and care of the future. It is a one-stop-shop for biodata analysis with rapid deployment without sacrifices on safety and privacy.see page
Technology center Human performance
This technology center offers human in-vivo measurement techniques to study human functionality from the level of organs to individuals as a whole. These can play an important role in the evaluation of new therapies and interventions at the patient level.see page