Research news at Radboudumc.
Laparoscopy reduces the number of adhesions but it is still too high14 January 2020
Adhesions after abdominal surgery cause too many re-admissions. Although keyhole surgery reduces the number of adhesions and the complications associated with them, the total disease burden remains high, as reported in The Lancet by RIHS researcher Richard ten Broek and colleagues.
Rubicon Grant for Marieke Klein14 January 2020
DCMN researcher Marieke Klein, theme Neurodevelopmental disorders, received a Rubicon Grant from the Dutch Organisation for Scientific Research (NWO). The Rubicon program gives young, highly promising researchers the opportunity to gain international research experience.
Radboud Talks 2020 scientific pitch competition14 January 2020
The next edition of Radboud Talks will take place in the spring. During this academic pitch competition, young researchers will be given the opportunity to share their stories with a large audience. In a three-minute presentation, you will talk about your research in a fun and accessible manner.
Rubicon Grant for Sami Mohammed14 January 2020
Former RIMLS researcher Sami Mohammed, theme Renal disorders, received a Rubicon Grant from the Dutch Organisation for Scientific Research (NWO). The Rubicon program gives young, highly promising researchers the opportunity to gain international research experience.
Review Sanne Frambach accepted by Pharmacological Reviews13 January 2020
In this review entitled 'Brothers in arms: ABCA1 and ABCG1-mediated cholesterol efflux as promising targets in cardiovascular disease treatment', RIMLS researcher Sanne Frambach, describe the possibilities for stimulating cellular efflux.
9 million euros made available for lifestyle research13 January 2020
Neuroscientist Esther Aarts has been awarded a Crossover grant from NWO for her MOCIA project. This grant will boost progress in lifestyle research for the elderly. MOCIA focuses on achieving a healthier brain during aging, and involves a public-private partnership.
Prostate cancer can now be diagnosed better using artificial intelligence9 January 2020
RIHS researchers Wouter Bulten and Geert Litjens have developed a ‘deep learning’ system that is better than most pathologists at determining the aggressiveness of prostate cancer. The Artificial Intelligence system taught itself to identify prostate cancer based on data from over 1200 patients.
European grant for rare neurological disease9 January 2020
Together with a consortium of European researchers, neurologist and Donders PI Bart van de Warrenburg and RIHS researcher Marjan Meinders have received a 2 million euro grant for research into rare neurological movement disorders: spastic ataxia.
Supplemental MRI screening for women with extremely dense breast tissue9 January 2020
In the New England Journal of Medicine, the DENSE trial study group including RIHS researchers Ritse Mann and Nico Karssemeijer showed that additional MRI after the nationwide breast screening, reduces interval breast cancer in women with extremely dense breast tissue.
p120-catenin-dependent collective brain infiltration by glioma cell networks7 January 2020
Pavlo Gritsenko and Peter Friedl, theme Cancer development and immune defense, report in Nature Cell Biology, that glioma cells infiltrate the brain by a collective network mechanism, which critically depends on p120 catenin. p120 thus represents a potential target to combat glioma.
Resistance of malaria parasites against artemisinin explained7 January 2020
Malaria parasites that are resistant to the commonly used malaria medicine artemisinin are a growing problem. How these parasites become resistant has now been uncovered by the RIMLS group of Richard Bartfai, theme Infectious diseases and global health, and published in Science.
JPI-AMR grant for Quirijn de Mast and Marien de Jonge6 January 2020
The JPI-AMR grant ‘Diagnostics and surveillance of antimicrobial resistance: development of tools, technologies and methods for global use’ has been awarded to Quirijn de Mast and Marien de Jonge), the Charles University Prague and the Kilimanjaro Christian Medical Centre in Moshi, Tanzania.
Niels Stensen Fellowship for Jorieke Weiden6 January 2020
Jorieke Weiden was recently awarded a grant from the Niels Stensen Fellowship. Since the 1960s, the Niels Stensen Fellowship has been awarded annually to outstanding researchers who recently received their PhD to enable them to gain research experience at a top university or institute abroad.
Simple tool provides insight into the average life expectancy for patients with dementia19 December 2019
A simple tool can quickly provide patients, with a dementia diagnosis, with more clarity about their average life expectancy. This tool is developed by Radboudumc in collaboration with the Karolinska Institute in Sweden.
UMC consortium brings Digital Research Environment to next phase19 December 2019
Radboudumc, Erasmus MC and UMC Utrecht will work together to bring the Digital Research Environment to the next phase. The ultimate goal: to make this online environment for the secure and fast management, analysis, sharing and storage of research data a national and international success.
Synopsis of the European Breast Guidelines on organized breast cancer screening programs19 December 2019
In Annals of internal medicine Mireille Broeders and colleagues from the European Commission Initiative on Breast Cancer (ECIBC) Guidelines Development Group provide a synopsis of recommendations on organized breast cancer screening programs for women aged 40 to 75 years.
Conversation analysis of video consultations vs face-to-face consultations19 December 2019
A video consultation is often about the benefits of a digital connection. But what does it mean for the conversation itself? Surgeon Martijn Stommel and his sister Wyke Stommel conducted research into specific parts of the conversations.
Theme Rare cancers paper award for Sven van den Bosch18 December 2019
The Radiother Oncology paper by researcher Sven van den Bosch and colleagues, won the first place in the paper award session of the theme Rare cancers. The paper competed with 4 other recent publications produced by radboudumc research groups.
Awarded KWF grants for Radboudumc researchers18 December 2019
KWF is investing 2.7 million euros in five different studies at Radboudumc. The awards are part of the new round of funding by DCS, in which over 34 million euros will be granted to Dutch cancer research. We congratulate our researchers with this funding and wish them success with their great work.
Mechanism exposed for increased stress sensitivity17 December 2019
Approximately seventy percent of the population carries a genetic variant of the so-called serotonin transporter gene. This genetic variant makes people more sensitive to stress and increases the risk of stress-related disorders, such as depression.
Kolff grants Dutch Kidney Foundation for Raphaël Duivenvoorden and Jitske Jansen17 December 2019
The Dutch Kidney Foundation supports talented postdocs and physician researchers through providing personal grants that support different phases of a research career. This year Raphaël Duivenvoorden and Jitske Jansen, theme Renal disorders, received a Kolff grant.
Galectin-9 controls plasma membrane integrity of dendritic cells16 December 2019
Laia Querol Cano, theme Cancer development and immune defense, has discovered how galectin-9, a sugar-binding membrane organiser, governs dendritic cell function by intracellularly modulating actin cytoskeleton. These findings are published in the latest issue of iScience.
PPP allowance by Health~Holland for Fons van de Loo16 December 2019
Fons van de Loo, theme Inflammatory diseases, has been granted a 3 year PPP Allowance made available by Health~Holland for the project ‘REFIT’. The goal of this project is to restore the barrier function, immunity and microbiome of the intestinal tract using extracellular vesicles from milk.
In order to maximize quality of life in pediatric psoriasis reaching for clear skin is necessary12 December 2019
In JAMA Dermatology, Bruins et al showed that greatest improvement in quality of life was achieved with 90% improvement of the Psoriasis Area and Severity Index (PASI) and 90% decrease of affected body surface area in a large cohort of children with psoriasis.
New insights into the initiation of T cell responses in the spleen11 December 2019
Carl Figdor and colleagues, theme Cancer development and immune defense, provide insights into the initiation of T cell responses in the spleen and their consequences for T cell differentiation. They have published their results in Proceedings of the National Academy of Sciences USA.
Dietrich-Knorr Prize for Hedi Claahsen-van der Grinten10 December 2019
Hedi Claahsen-van der Grinten, theme Vascular damage, received the Dietrich-Knorr prize 2019 for the best published paper in the field of adrenal research, for her publication in the Journal of Clinical Endocrinology & Metabolism.
'Stofwisselkracht' grant for Paola de Haas and Alessandra Cambi5 December 2019
Paola de Haas and Alessandra Cambi, theme Nanomedicine, have recently been awarded a grant from ‘Stichting Stofwisselkracht’ for their project entitled “Identification of immune-related symptoms in Congenital Disorders of Glycosylation”.
Newly appointed Junior Principal Clinicians3 December 2019
The appointed junior Principal Clinician for RIMLS are Heidi Zweers-van Essen and Jenneke Leentjens. These caregivers are at the forefront of renewing patient care and take the lead in the development and realization of the Radboudumc vision.
Exploration meeting Academic Alliance on Oncology2 December 2019
Within the Academic Alliance, the Maastricht UMC+ and Radboudumc are already working together in several areas. And this is happening in more and more fields. On 27 November researchers from both umc's met during the fourth Exploration meeting, this time with the theme: Oncology.
Two DCMN researchers in top 1 percent by citations28 November 2019
Jan Buitelaar and Christian Beckmann made it to this year’s list of highly cited researchers. Researchers in this list are selected for their exceptional research performance and are regarded to have had a major impact on fellow scientists.
Two RIHS researchers in top 1 percent by citations28 November 2019
Bart-Jan Kullberg and Jacques Meis, made it to this year’s list of highly cited researchers. Researchers in this list are selected for their exceptional research performance and are regarded to have had a major impact on fellow scientists.