News Research

How are the Dutch Olympians prepared for the heat and humidity of Tokyo?

Personal heat preparedness advice for Dutch Olympic athletes

Nijmegen literally puts Digital Health on the map Flourishing ecosystem gets its own interactive overview

Digital Health is thriving in the Nijmegen region, where it contributes to better care and health and also creates jobs. To bring developers and end users even closer together, The Economic Board and the Radboudumc are introducing the Interactive Digital Health map.

Marijn de Bruin appointed professor of Behavioural medicine & Health psychology

Michiel Vermeulen and Klaas Mulder receive funding from ZonMw for a collaborative project using stem cell-based models

Michiel Vermeulen and Klaas Mulder, theme Cancer development and immune defense, receive funding from ZonMw for a collaborative project to develop a stem cell based model to study early human embryogenesis.

Launch of UNITE4TB partnership marks a new era in Tuberculosis treatment development

The partnership will accelerate the development of new Tuberculosis (TB) drug regimens as part of the Innovative Medicines Initiative (IMI), a public-private European Research & Development Consortium

Henk Schers appointed professor of Regional Network Formation of General Practice

His research focuses on innovations in the collaboration between healthcare providers from inside and outside the hospital

ZonMw funding for PSIDER program

Michiel Vermeulen, Klaas Mulder and Nael Nadif Kasri receive funding from ZonMw for a collaborative project to develop a stem cell based model to study early human embryogenesis.

VIDI grants for researchers of Radboud university medical center

Several Radboudumc researchers have been awarded a VIDI grant by the Dutch Organisation for Scientific Research (NWO). They each receive a sum of 800,000 euros, which they will use over the next five years to develop their own innovative line of research and to set up a research group.

Newborn screening in sight through the discovery of novel disease biomarkers by new technique

To identify new biomarkers that can be used in the newborn screening protocol, also known as the neonatal heel prick, Karlien Coene and colleagues joined forces with scientists at the Radboud University’s FELIX laser laboratory. They published their findings in The Journal of Clinical Investigation.

Researchers identify missing ‘switch’ that controls expression of essential genes Published in Nature

Michiel Vermeulen and colleagues identified that a long-sought-after transcription factor that regulates essential genes in the mouse and human genome. Published in Nature.

Radboud Pluim for Myrthe Swaak

''Extraordinary accomplishments, strong commitment and a positive and constructive attitude” were the words used to praise senior communications advisor for science, Myrthe Swaak, when she received the Radboud Pluim.

RIMLS PhD retreat Registration open now!

As announced previously, this year’s RIMLS PhD retreat will take place online from 17-19 Nov 2021, in collaboration with the New Frontiers Symposium.

New study: Lack of consideration of sex and gender in COVID-19 clinical studies

Publication in Nature Communications

Q fever antibody does not predict disease progression

Joint study by Radboudumc, Jeroen Bosch Hospital and UMC Utrecht.

Finding better ways to diagnose and treat IgA nephropathy

IgA nephropathy is a slowly progressing disease that causes kidney damage and leads to kidney failure in about 25-50% of patients. The reason why some people develop IgA nephropathy is unclear and there is no effective treatment.

New culture method reveals how cancer cells bypass immune system

Publication in Cancer Immunology Research

Radboudumc receives prestigious Edmond J. Safra Fellowship

Fellowship to train a new movement disorder clinician-researcher (a neurologist with additional education and expertise in Parkinson’s and related diseases)

Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum in Nature Communcations

Using complexome profiling Felix Evers, Taco Kooij and colleagues unravel the composition of mitochondrial oxidative phosphorylation complexes of asexual and sexual blood-stage malaria parasites, showing abundance differences and a metabolic switch central to gametocyte development and function.

DNA from 34-thousand-year-old skull helps research on the immune system

Scientists at the Radboudumc have gained knowledge about genetic variation in the DNA of mankind of that time thanks to DNA research from a 34-thousand-year-old skull found in a Romanian cave.

Diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis in taskforce report

Diagnosis and management of COVID-19 associated pulmonary aspergillosis (CAPA) is challenging, so Paul Verweij and colleagues set a goal to develop practical guidelines.

RIMLS introductory course: ''In the Lead of your PhD" Online and personal

During last week’s introductory course, new RIMLS PhD candidates worked on personal development from a comfortable chair at home.

Radboudumc helps people go into surgery fitter Fit4Surgery available in steps throughout the hospital

Getting patients in the best possible shape for surgery. With that goal in mind, the Radboudumc started the Fit4Surgery program for people with colon cancer two years ago. And with success.

Biomarkers for pyridoxine-dependent epilepsy identified by untargeted metabolomics and infrared ion spectroscopy

Karlien Coene, theme Metabolic Diseases, and colleagues published in the Journal of Clinical Investigation that untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy.

Magnesium deficiency increases the risk of cardiovascular disease in diabetic patients

Publication in Diabetes Care.

Two science talents to foreign top institutes with Rubicon

Rubicons for Michelle Brouwer and Guido van Mierlo

Radboud university medical center and Astherna join forces for new therapy for Stargardt disease

RNA therapy for patients with a severe inherited retinal disease

Children with asymptomatic malaria a ‘hidden risk’ to disease control efforts Publication in The Lancet Infectious Diseases

The international dataset for colorectal local excisions is published

Iris Nagtegaal and colleagues presented their first paper on the colorectal cancer dataset and published this in the journal Gastroenterology.

Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis

Intan Dewi and Frank van de Veerdonk published in Cell Reports Medicine that Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis.

ZonMw Open Competition Grants for several Radboud researchers

Four teams including researchers from Radboudumc and Radboud University receive a ZonMw Open Competion grant. Each proposal has a maximum budget of 750K euros.

ZonMw Open Competition Grant for Annemiek van Spriel and Piet Gros

Annemiek van Spriel, theme cancer development and immune defense, together with Piet Gros, Dept. of Chemistry, Utrecht University obtained a ZonMw Open Competition Grant to investigate IL-6 receptor structure and signalling in tumor cells.

New ultra-high field MRI system available for Radboudumc and Radboud University

Recently, the Hahn institute in Essen has received a new heart: a 20-ton ultra-high-field MRI scanner from Siemens Healthcare with a magnetic field strength of 7 Tesla. The new CE-approved scanner is ready for business, and projects on body and brain imaging are starting up.

On the prevalence of cerebral amyloid angiopathy a systematic review and meta-analysis

Published in ‘Alzheimers and Dementia’, researchers at Radboudumc performed a systematic review and meta-analysis on the prevalence of Cerebral Amyloid Angiopathy. They scrutinized and analyzed 170 publications, comprising publications using either a neuroimaging or a neuropathological approach.

Retina-on-chip modeling and treating eye diseases in a dish

Alex Garanto, together with Anneke den Hollander and Andries van der Meer (UTwente) have received 1,17M€ to develop a retina-on-chip model to improve our understanding in eye diseases and to develop treatments against them.

New method to prevent ovarian cancer increases quality of life

Researchers at Radboudumc have shown that quality of life is better in women with a BRCA1 or BRCA2 mutation after fallopian tube removal with delayed ovarian removal to prevent ovarian cancer.

Radboud Pluim for Dagmar Eleveld-Trancikova Policy advisor of the three research institutes

Radboudpluim for research policy adviser Dagmar Eleveld-Trancikova.

Epidemiology and reporting characteristics of preclinical systematic reviews in PLoS Biology

Kim Wever, researcher of the department of Health Evidence and an international team published the article 'Epidemiology and reporting characteristics of preclinical systematic reviews' in PLoS Biology.

First Dutch professor of infectious disease outbreaks at Radboud university medical center

Chantal Bleeker-Rovers about research on coronavirus, Q fever and other infectious diseases outbreaks

Gut microbiota alleviates effects of stress on cognition

Researchers from the Radboudumc and Donders Institute have shown that the gut microbiota is involved in the protecting effects of probiotics on cognitive performance in acute stress circumstances. Their results are now published in Translational Psychiatry.

A hybrid in silico and tumor-on-a-chip approach to model targeted protein behavior in 3D microenvironments

Valentina Palacio-Castañeda published in Cancers about modeling the behavior of targeted proteins in 3D microenvironments by approaching a hybrid in silico and tumor-on-a-chip.

Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses

Rosanne van Deuren published her study in Genome Medicine which shows that functionally grouping common and rare genetic variants enables the elucidation IL-1-mediated biological mechanisms, specifically, for IL-1β and IL-6 cytokine responses induced by various stimuli.

Vaccination with immune cells boosts immune system after stem cell transplantation

Jesper van Eck van der Sluijs and other researchers have developed a method for growing different types of dendritic cells: the cells of the immune system that specialize in processing foreign substances (including tumor proteins) and presenting them to killer cells.

Maarten van der Weijden Foundation selects Radboudumc research for recruitment campaign Preventing cancer in people with intellectual disabilities

The Maarten van der Weijden Foundation, founded by top swimmer Maarten van der Weijden, supports several innovative cancer research projects each year. One of the three selected this year is Radboudumc's research into the prevention of cancer in people with intellectual disabilities.

Aggressive periprocedural hydration + rectal NSAID: no reduction in incidence of post-ERCP pancreatitis

Aggressive fluid hydration plus non-steroidal anti-inflammatory drugs versus non-steroidal anti-inflammatory drugs alone for post-endoscopic retrograde cholangiopancreatography pancreatitis (FLUYT): a multicentre, open-label, randomised, controlled trial.

Families with a child with ADHD can benefit from mindfulness training

Publication in Journal of Child Psychology and Psychiatry

Long-term symptoms more common after Lyme disease

Research of RIVM, Radboud university medical center and Amsterdam UMC

4th ENABLE symposium a big success

RIMLS PhD candidates co-organized this unique event with three other European research institutes (IRB Barcelona, CPR Copenhagen, SEMM Milan), which was facilitated by a competitive Horizon 2020 grant.

Innovative therapy developed for the future treatment of hereditary (deaf)blindness

Researchers from the department of Otorhinolaryngology, headed by Erwin van Wijk, developed a novel therapeutic strategy to halt the progression or to prevent vision loss in patients as a consequence of USH2A exon 13 mutations.

Lisanne Gommers nominated for James Lind Prize Your vote is needed

Her PhD research entitled "Digesting the role of the gut microbiome in proton pump inhibitor (PPI)-induced hypomagnesemia'' has been nominated for the James Lind Prize. You can vote now until 8 June.