Research news at Radboudumc.
Researchers and industry join forces to unravel and treat autism Public-private project AIMS-2 receives 110 million euros from IMI12 July 2018
In a large public-private project, supported by 110 million euros by the IMI, a large consortium of researchers will search for biomarkers with which people with autism can be divided into clear subgroups.
Biodegradable nanoreactors demonstrate ROS shielding in human-complex-I-deficient fibroblasts9 July 2018
Researchers of the Radboudumc and colleagues have successfully developed enzyme-loaded polymersomal nanoreactors capable of undergoing cellular integration in a controlled fashion and, subsequently, function as synthetic organelles.
Veterinary drug can prevent outbreaks of malaria and Zika in humans5 July 2018
Drugs that protect pets against ticks and fleas can also be used to prevent outbreaks of malaria, Zika and dengue fever in humans. This was the conclusion of an article by scientists from TropIQ Health Sciences, together with English and American colleagues, and published in the journal PNAS.
Pneumococcal DNA predicts course of infection4 July 2018
In Clinical Infectious Diseases, Radboudumc researchers describe several pneumococcal genes predicting whether a patient runs the risk of developing meningitis or dying from the disease. Use of such genetic tests can improve infection diagnostics.
Making choices in healthcare is difficult but citizens will show politics the way22 June 2018
Well-informed citizens are not just aware of the financial necessity of making choices in healthcare, they are also prepared to make these choices. They do so by providing concrete criteria and examples, which serve as guidelines for politicians.
How to measure >70 (phospho-) protein levels via sequencing DNA-tagged antibodies21 June 2018
Jessie van Buggenum and Klaas Mulder, theme Cancer development and immune defense, show in Nature Communications how immuno-detection by sequencing uses antibodies tagged with DNA barcodes and high-throughput sequencing to detect up to 70 phospho-proteins in skin stem cell.
A low cholesterol level is not a good thing21 June 2018
Research shows that low cholesterol can also be harmful. Researchers from Radboudumc and their Australian and American colleagues discovered a new metabolic defect, producing very low cholesterol levels. This causes brain anomalies, developmental delay, epilepsy and typical facial deformities.
Small vessel disease often affects entire brain Nijmegen researchers present new framework for serious disease13 June 2018
Radboud university medical center researchers state that damage to the smallest cerebral vessels can have effects throughout the brain. Small vessel disease (SVD) should therefore no longer be regarded as a local but as a generalized brain disorder.
Rick Helmich receives 693,000 dollar from Michael J Fox Foundation for Parkinson research12 June 2018
Rick Helmich, researcher at the Donders Center for Medical Neurosciences, receives a grant of $ 693,000 from the Michael J Fox Foundation. With this he can investigate the brain mechanisms that are responsible for the progression of Parkinson's disease.
First steps toward new cancer vaccine22 May 2018
In order to reduce cancer mortality, there is a great need for new treatments. In the last few years, there have been many studies into immunotherapy. Tim Hutten, theme Cancer development and immune defense, has been studying the interactions between immune cells and cancer.
Decision-making in extreme prematurity awarded by ZonMW16 May 2018
Rosa Geurtzen was awarded as appreciation for her role in a project that contributes to making effective choices in healthcare. She received the scholarship for the PreCo study, in which prenatal counseling in extreme preterm birth is optimized.
The National Healthcare Institute (ZIN) provides insight in the displacement of healthcare25 April 2018
Displacement of care is difficult to assess. On behalf of the National Healthcare Institute, a consortium led by the Radboudumc has therefore carried out research into displacement of care in Dutch healthcare.
Honorary doctorate in Aalborg for Nico Verdonschot25 April 2018
Verdonschot has a global reputation in the field of orthopaedic biomechanics. Besides professor in the Radboudumc, he is the scientific director of the TechMed Centre, and professor of Biomechanical Implants at the department of Biomechanical Engineering at the UT.
Longer dives because of larger spleen Seanomads in Southeast Asia have larger spleens because of natural selection20 April 2018
In the journal Cell, researchers of Radboudumc and international colleagues, report that the extraordinary diving abilities of the Bajau may be thanks in part to their unusually large spleens.