Research news at Radboudumc.
Nijmegen literally puts Digital Health on the map Flourishing ecosystem gets its own interactive overview22 July 2021
Digital Health is thriving in the Nijmegen region, where it contributes to better care and health and also creates jobs. To bring developers and end users even closer together, The Economic Board and the Radboudumc are introducing the Interactive Digital Health map.
Michiel Vermeulen and Klaas Mulder receive funding from ZonMw for a collaborative project using stem cell-based models15 July 2021
Michiel Vermeulen and Klaas Mulder, theme Cancer development and immune defense, receive funding from ZonMw for a collaborative project to develop a stem cell based model to study early human embryogenesis.
VIDI grants for researchers of Radboud university medical center14 July 2021
Several Radboudumc researchers have been awarded a VIDI grant by the Dutch Organisation for Scientific Research (NWO). They each receive a sum of 800,000 euros, which they will use over the next five years to develop their own innovative line of research and to set up a research group.
Newborn screening in sight through the discovery of novel disease biomarkers by new technique8 July 2021
To identify new biomarkers that can be used in the newborn screening protocol, also known as the neonatal heel prick, Karlien Coene and colleagues joined forces with scientists at the Radboud University’s FELIX laser laboratory. They published their findings in The Journal of Clinical Investigation.
Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum in Nature Communcations1 July 2021
Using complexome profiling Felix Evers, Taco Kooij and colleagues unravel the composition of mitochondrial oxidative phosphorylation complexes of asexual and sexual blood-stage malaria parasites, showing abundance differences and a metabolic switch central to gametocyte development and function.
Radboudumc helps people go into surgery fitter Fit4Surgery available in steps throughout the hospital28 June 2021
Getting patients in the best possible shape for surgery. With that goal in mind, the Radboudumc started the Fit4Surgery program for people with colon cancer two years ago. And with success.
Biomarkers for pyridoxine-dependent epilepsy identified by untargeted metabolomics and infrared ion spectroscopy24 June 2021
Karlien Coene, theme Metabolic Diseases, and colleagues published in the Journal of Clinical Investigation that untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy.
ZonMw Open Competition Grant for Annemiek van Spriel and Piet Gros15 June 2021
Annemiek van Spriel, theme cancer development and immune defense, together with Piet Gros, Dept. of Chemistry, Utrecht University obtained a ZonMw Open Competition Grant to investigate IL-6 receptor structure and signalling in tumor cells.
New ultra-high field MRI system available for Radboudumc and Radboud University10 June 2021
Recently, the Hahn institute in Essen has received a new heart: a 20-ton ultra-high-field MRI scanner from Siemens Healthcare with a magnetic field strength of 7 Tesla. The new CE-approved scanner is ready for business, and projects on body and brain imaging are starting up.
On the prevalence of cerebral amyloid angiopathy a systematic review and meta-analysis10 June 2021
Published in ‘Alzheimers and Dementia’, researchers at Radboudumc performed a systematic review and meta-analysis on the prevalence of Cerebral Amyloid Angiopathy. They scrutinized and analyzed 170 publications, comprising publications using either a neuroimaging or a neuropathological approach.
Epidemiology and reporting characteristics of preclinical systematic reviews in PLoS Biology7 June 2021
Kim Wever, researcher of the department of Health Evidence and an international team published the article 'Epidemiology and reporting characteristics of preclinical systematic reviews' in PLoS Biology.
Gut microbiota alleviates effects of stress on cognition3 June 2021
Researchers from the Radboudumc and Donders Institute have shown that the gut microbiota is involved in the protecting effects of probiotics on cognitive performance in acute stress circumstances. Their results are now published in Translational Psychiatry.
Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses2 June 2021
Rosanne van Deuren published her study in Genome Medicine which shows that functionally grouping common and rare genetic variants enables the elucidation IL-1-mediated biological mechanisms, specifically, for IL-1β and IL-6 cytokine responses induced by various stimuli.
Vaccination with immune cells boosts immune system after stem cell transplantation1 June 2021
Jesper van Eck van der Sluijs and other researchers have developed a method for growing different types of dendritic cells: the cells of the immune system that specialize in processing foreign substances (including tumor proteins) and presenting them to killer cells.
Maarten van der Weijden Foundation selects Radboudumc research for recruitment campaign Preventing cancer in people with intellectual disabilities1 June 2021
The Maarten van der Weijden Foundation, founded by top swimmer Maarten van der Weijden, supports several innovative cancer research projects each year. One of the three selected this year is Radboudumc's research into the prevention of cancer in people with intellectual disabilities.
Aggressive periprocedural hydration + rectal NSAID: no reduction in incidence of post-ERCP pancreatitis1 June 2021
Aggressive fluid hydration plus non-steroidal anti-inflammatory drugs versus non-steroidal anti-inflammatory drugs alone for post-endoscopic retrograde cholangiopancreatography pancreatitis (FLUYT): a multicentre, open-label, randomised, controlled trial.
Innovative therapy developed for the future treatment of hereditary (deaf)blindness26 May 2021
Researchers from the department of Otorhinolaryngology, headed by Erwin van Wijk, developed a novel therapeutic strategy to halt the progression or to prevent vision loss in patients as a consequence of USH2A exon 13 mutations.