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HFSP Grant for Johannes Textor
30 March 2020Johannes Textor, theme Cancer development and immune defense, has been awarded a program grant of 1 million US dollars by The Human Frontier Science Program (HFSP) to investigate how T cells navigate extremely dense environments using experiments, modeling and methods from pedestrian dynamics.
Ritalin enhances your ability to do tasks by making you more motivated
26 March 2020A new study uncovers how stimulants like Ritalin work in the brain, and it challenges some misconceptions for its recreative use. The collaboration between Radboudumc and Brown University (USA) was published in the journal Science.
Dealing with COVID-19 in low- and middle-income countries
26 March 2020RIHS researcher Joost Hopman believes that low-and middle-income countries should intensify their preparedness for a possible COVID-19 outbreak. This was the core message of an opinion article that he wrote at the request of the medical journal JAMA.
Physiotherapy is important to the recovery of patients with the coronavirus
26 March 2020Patients who have been infected with the coronavirus and admitted to the hospital for this reason should receive physiotherapy as soon as their condition allows. This is the view expressed by physiotherapists and researchers from the Radboudumc in a set of joint treatment recommendations.
Healthcare utilization and regional variation of end-of-life hospital care in Dutch cancer patients
26 March 2020In International Journal of Quality Health Care RIHS researcher Femke Atsma showed high healthcare utilization and medical variation in End of Life care in Cancer patients, which was not associated with GP care or long term care.
Study into better protection for healthcare workers against coronavirus infection
19 March 2020Radboudumc and UMC Utrecht will investigate whether health care workers are better protected against the coronavirus after a vaccination against tuberculosis (BCG vaccine). This vaccine does not directly protect against the coronavirus, but provides a boost to the immune system.
Differences in the placental disposition of TNF inhibitors uncovered
19 March 2020In Clinical Pharmacology and Therapeutics, researchers from the Depts. of Pharmacology and Toxicology, Obstetrics and Gynecology, and Health Evidence, in collaboration with Sanquin Diagnostic Services, investigated the placental handling of the TNF inhibitors infliximab and etanercept.
The effect of pregnancy on the pharmacokinetics of dolutegravir in women living with HIV
17 March 2020In Clinical infectious diseases RIHS researchers Pauline Bollen, Jolien Freriksen, Angela Colbers and David Burger together with researchers of the PANNA network showed that dolutegravir use in pregnancy results in effective plasma concentrations.
Greater attention to sex and gender needed in healthcare
13 March 2020Scientific research shows that both sex and gender influence health behavior and impact disease development, having an effect on its diagnosis, treatment, and long-term effects as well. That is what RIHS researcher Sabine Oertelt-Prigione states in The Lancet EClinical Medicine.
Interleukin-37 plays a rol in the pathogenesis and treatment of gout
11 March 2020RIMLS researchers Leo Joosten, Viola Klück and Rosanne van Deuren, in collaboration with the Dept. of Human Genetics, discovered that rare genetic variants in interleukin-37 link the anti-inflammatory cytokine to the pathogenesis and treatment of gout.
NWO Open Competition ENW - KLEIN grant for Jenny van der Wijst
9 March 2020KLEIN grants offer researchers the possibility to realize curiosity-driven, fundamental research and elaborate creative and risky ideas. For this project, Jenny is seeking an enthusiastic postdoc to join her team working on ion channels.
FET-OPEN grant for Toin van Kuppevelt and Willeke Daamen
6 March 2020A grant of 592 kEuro has been awarded to Toin van Kuppevelt and Willeke Daamen, theme Reconstructive and regenerative medicine, for a Horizon 2020 FET-OPEN project entitled “Heparin and heparan sulphate: from sequence determination to therapeutic strategies for Parkinson’s disease”.
Electronic nose smells precursor of oesophageal cancer
5 March 2020A portable electronic nose can effectively detect precursors of oesophageal cancer, reported by RIHS researchers Yonne Peters and Peter Siersema in the medical science journal GUT. This was demonstrated in an initial study involving more than four hundred patients.
Prevention of tuberculosis among people with diabetes the first clinical trial globally
5 March 2020In recent years it has become clear that diabetes is an important factor driving the global tuberculosis epidemic. Diabetes also leads to more severe and recurrent disease and more TB deaths. The first clinical trial to prevent TB among people with diabetes will be started by the PROTID consortium.
Plugging the gap ZonMw/Health Holland grant
3 March 2020RIMLS en RIHS researchers Willeke Daamen, Frank Vandenbussche, Joris van Drongelen, Toin van Kuppevelt and Janneke Grutters have been granted 1.3 million euro for the development and evaluation of a new technology to prevent premature rupture of fetal membranes (iPPROM).
People-like-me treatment for intermittent claudication Personalized approach for patients
27 February 2020Radboudumc, with the University of Colorado, ClaudicatioNet and Harteraad, has developed a method to better treat people with intermittent claudication. This method, by RIHS researcher Thomas Hoogeboom among others, enables physiotherapists to coordinate the care process with the patient better.
Jurgen Fütterer appointed Professor of Image-Guided Oncological Interventions
26 February 2020RIHS researcher Fütterer is an interventional radiologist and an expert in the field of cancer imaging techniques, image-guided interventions and robotics. He is also Professor at the Robotics and Mechatronics Group at the University of Twente.
NWO open call GROOT grant for Michiel Vermeulen
24 February 2020Michiel Vermeulen, theme Cancer development and immune defense, received a 300,000 EUR grant within the NWO-GROOT consortium. He will use mass spectrometry-based proteomics and interaction proteomics applications to study proteome and gene expression dynamics during early C. Elegans development.
Dutch Brain Foundation grant for EENnacoma
20 February 2020Lavrijsen and Van Erp: ‘This grant will facilitate practice-based research, professionalization and further academization of EENnacoma, and links between different health care and research institutions all for the benefit of people with prolonged disorders of consciousness and their families.'
RIHS Awards Ceremony five winners
19 February 2020On 18 February the RIHS 'Koek & Zopie' event took place. In front of an audience of more than 125 colleagues, RIHS awardees accepted their awards for the best PhD thesis, the research product with the highest impact on society, the best peer-reviewed publication and the Supervisor of the year 2019.
Preserved specific force in facioscapulohumeral muscular dystrophy
19 February 2020DCMN researcher Saskia Lassche et al., theme Disorders of Movement, recently showed in Neurology that remaining muscle fibers in Facioscapulohumeral muscular dystrophy (FSHD) patients have normal muscle strength, even in severely affected muscles.
Researchers investigate how stem cells affect the immune system
18 February 2020RIMLS researchers Irma Joosten and Renate van der Molen, participating in an European study into the treatment of brain damage in premature babies. Is it possible to limit or even partly repair the damage with stem cells? They focus primarily on the effect of those stem cells on the immune system.
Five ZonMw ‘Off Road’ grants for Radboudumc researchers
17 February 2020Benoit Besson, Annemarie Boleij, Jonne Doorduin, Jorik Nonnekes and Sara Roig Merino have each received an ZonMw ‘Off Road’ grant of €100,000. The grants are intended for biomedical health researchers who dare to go off the beaten track in their search for new insights and unexpected breakthroughs.
Dutch Kidney Foundation PhD grant for Johan van der Vlag and Tom Nijenhuis
14 February 2020Johan van der Vlag and Tom Nijenhuis, theme Renal disorders, received this grant for their joint research project “Targeting a novel paracrine signaling pathway between glomerular endothelium and podocytes to treat glomerular injury”.
KNAW Early Career Award for Geert Litjens
13 February 2020Twelve young researchers received the Early Career Award from KNAW on 4 february. One of them is RIHS researcher Geert Litjens. The Award is aimed at researchers in the Netherlands at the start of their career who are capable of developing innovative and original research ideas.
Interactive career day for Postdocs and PhD candidates
13 February 202045 Postdocs and PhD candidates attended the first Interactive career day organised by Janssen Pharmaceutica, to learn more about career perspectives and R&D activities that on the longer term can lead to ideas and potential future collaboration.
SPL Medical starts clinical trial with contrast agent ferrotran
11 February 2020SPL Medical is starting an international registration study for its contrast agent Ferrotran. The study is being conducted in ten hospitals in Germany, Switzerland and the Netherlands. RIHS researcher Jelle Barentsz discovered the value of this drug in patients with lymph node metastases.
Khondrion begins study on optimal dosage of new drug
10 February 2020Pharmaceutical company Khondrion, a spin-off from Radboudumc, has taken another important step in the development of its drug sonlicromanol. The first patients have used the drug as part of a phase 2b study, which focuses on determining the optimum dose and efficacy.
Human pDCs attract cytolytic lymphocytes in anti-cancer vaccination
6 February 2020RIMLS researchers Jasper van Beek and Jolanda de Vries, theme Cancer development and immune defense, discovered that pDCs can efficiently recruit cytolytic immune effector cells, a property that could be exploited in anti-cancer vaccines. They have published these findings in Cell Reports.
King Willem-Alexander meets up with Judith Wolf about the causes of doubling number of homeless people
6 February 2020King Willem-Alexander and State Secretary Paul Blokhuis of Health, Welfare and Sport (Ministry of VWS) paid a working visit to Weert on 21 January in the context of shelter for the homeless and day care. During his visit the King and State Secretary spoke with RIHS researcher Judith Wolf.
Research Integrity Round with Frank Miedema
6 February 2020Guest speaker on 9 March 2020 is Frank Miedema, Vice Rector for research and chair of the Utrecht University Open Science program. He is one of the initiators of Science in Transition. All students, PhD candidates and senior researchers are invited to attend. Please register via the website.
ZonMw funding for teams of Michiel Vermeulen and Jolanda de Vries
4 February 2020The awarded research projects of RIMLS researchers Michiel Vermeulen, Jolanda de Vries, Gerty Schreibelt and Martijn Verdoes and colleagues will initiate new research lines and collaborations between various research groups.
General practitioners rarely order images for back problems
4 February 20208% Of all general practitioners regularly order imaging for patients who have lower-back pain without severe symptoms. Such imaging does not contribute to the treatment. This is indicated by the results from the Doen of Laten? project, a study conducted by Radboudumc, the LUMC and VGZ Cooperation.
New Guidelines for the detection of prostate cancer MRI instead of tissue samples
3 February 2020The module on diagnostic prostate MRI for the NVU guidelines for prostate carcinoma took effect on 29 January 2020. The development of these guidelines is due in part to the efforts of RIHS researcher Jelle Barentsz and Ivo Schoots (Erasmus MC).
