Research news at Radboudumc.
Exercise prevents new cardiovascular diseases4 March 2021
Exercise lowers the risk of glucose intolerance, obesity, elevated cholesterol and hypertension. The risk of new cardiovascular diseases can be lowered by an individual exercise guideline, argues epidemiologist Esmée Bakker in her dissertation on March 4.
Aart Schene appointed honorary member Dutch Psychiatric Association3 March 2021
Aart Schene, theme Stress-related disorders, has received the honorary membership of the Dutch Association for Psychiatry (NVvP). The Professor of Psychiatry received the award because of his extraordinary efforts throughout his career to improve the quality of care for psychiatric patients.
Water as a new tool for cardiac screening for chest pain2 March 2021
Patients with chest pain not caused by a narrowing of the coronary arteries often do not know the cause of their symptoms. Scientists at the Radboudumc have successfully used a new technique to investigate other causes in the coronary arteries of the heart.
Real-time dialogue with a dreaming person is possible25 February 2021
Dreams take us to what feels like a different reality. They also happen while we're fast asleep. So, you might not expect that a person in the midst of a vivid dream would be able to perceive questions and provide answers to them. But a new international study shows that, in fact, they can.
Online, socially distanced, or pre-pandemic style... “In the Lead” is always inspiring and helpful. By Özlem Bulut25 February 2021
Every new RIMLS PhD candidate shares one common experience: an amazing 2-day retreat where you make friends, discover yourself, and get inspired. At least, that was the case pre-pandemic. No more communal retreats in an old convent, but the course still continues helping new PhDs online.
SATB1 - Three classes of mutations and their unique rare diseases18 February 2021
Recent advances in DNA sequencing technologies have made it possible to uncover the causes of multiple rare diseases. A new collaborative study describes how three classes of mutation within the same gene result in different neurodevelopmental disorders.
Trained immunity: a tool for reducing susceptibility to and the severity of SARS-CoV-2 infection17 February 2021
In a review in Cell Mihai Netea, Frank van de Veerdonk, Reinout van Crevel and Jorge Dominguez Andres propose that induction of trained immunity by whole-microorganism vaccines may represent an important tool for reducing susceptibility to and severity of SARS-CoV-2.
Radboudumc and Quirem Medical sign cooperation agreement17 February 2021
Radboudumc and Quirem Medical signed an agreement for joint research. The agreement includes several existing and future projects based on small radioactive spheres. Enhanced cooperation should improve the treatment of cancer patients and stimulate research into new applications.
Lab of Martijn Agterberg stars in prize winning photograph10 February 2021
With this photograph, Koen Verheijden has won De Zilveren Camera in the category Nature and Science. It was taken for the Dutch newspaper Trouw, and shows the mobile lab of the Radboudumc researcher Martijn Agterberg, where bumblebees are studied to improve hearing aids for humans.
Cell-type specific changes induced by culturing on microfluidic chips.10 February 2021
A collaborative TURBO (Twente University RadBoudumc Opportunities) project, recently published in Scientific Reports, developed an organ-on-a-chip device which can be used for modelling the neurovascular unit (NVU).
Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates9 February 2021
Gert-Jan Veenstra and Simon van Heeringen published in the Embo Journal. Their results show that transcription factors cooperate in a combinatorial fashion in generally open chromatin to orchestrate zygotic gene expression.
Saskia Middeldorp appointed professor9 February 2021
Effective 1 January, 2021, internist Saskia Middeldorp has been appointed Professor of Internal Medicine at Radboud University/Radboudumc. This chair is part of the position of Head of the Department of Internal Medicine that she has held since 1 January 2021.
Geriatric syndromes and multimorbidity in older adults with psychiatric disorders An integrated perspective4 February 2021
This thesis includes four studies on prevalence and implications of geriatric syndromes and multimorbidity (chronic health conditions) in older patients with different psychiatric disorders and in different settings.
ZonMw grants to study optimal use of COVID-19 vaccines in patients with impaired immune systems3 February 2021
How do people with reduced immunity, especially kidney patients, react to a COVID-19 vaccination? And how can patients with peripheral arterial disease be helped by DNA testing? Our researchers received grants from ZonMw to make these studies possible.
Establishing the biggest database of pathology images to accelerate the development of artificial intelligence in medicine.2 February 2021
A new consortium of the EU Innovative Medicines Initiative (IMI) aims to establish the biggest database of pathology images to accelerate the development of artificial intelligence in medicine.
Four new professors explain the need for cooperation in developmental neuroscience27 January 2021
In the past, developmental neuroscience was not a field in which people from different disciplines cooperated very much. However, in recent years, the approach has been gradually changing. Four newly appointed professors at Radboudumc/ the Donders Institute understand the importance of teaming up.
Rob Aarnoutse is appointed as professor in Translation pharmacology of antimicrobial agents in particular drugs for tuberculosis25 January 2021
Hospital pharmacist and clinical pharmacologist Rob Aarnoutse is appointed as professor in ‘Translation pharmacology of antimicrobial agents, in particular drugs for tuberculosis’ at Radboud University / Radboudumc, starting 16 November 2020.
Oral health research makes significant impact at the 148th WHO Executive Board meeting25 January 2021
During the 148th session of the World Health Organization (WHO) Executive Board meeting, the Member States passed a game-changing resolution on oral health. WHO Director General Dr Tedros Adhanom Ghebreyesus called it a “landmark resolution”.
Increase radio- and immunotherapy efficacy by targeting hypoxia21 January 2021
In a paper recently accepted by Clinical Cancer Research, Daan Boreel, together with Paul Span, Sandra Heskamp, Gosse Adema and Jan Bussink, reviews the therapeutic potential of decreasing the lack of oxygen (hypoxia) often found in solid tumors.
Radiation boost lowers risk of prostate cancer recurrence21 January 2021
An additional external-beam radiation dose delivered directly to the tumor can benefit the prospects of men with non-metastatic prostate cancer, without causing additional side effects. The risk of relapse within five years for these men is smaller than for men who did not receive this boost.
New research through grants for Radboudumc researchers14 January 2021
Several researchers at the Radboudumc have received grants to start new studies, including on rare diseases, liver disease and cancer metastases. These are grants from the Dutch Research Council, European Joint Programme on Rare Diseases and the Gastric Liver Disease Foundation.
Should we prepare for a corona-related depression wave? Indira Tendolkar and Eric Ruhé talk about their research projects13 January 2021
Since the outbreak of the SARS-CoV-2, many of us have been staying at home in order to limit our social interactions, to keep ourselves and others safe from the virus. Yet, there’s also concern about what social distancing and anxiety generated by media reports are doing to people's mental health.
RIMLS online award ceremony proudly presenting the winners13 January 2021
In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony.
Cooling vests alleviate perceptual heat strain perceived by COVID-19 nurses11 January 2021
Wearing cooling vests during a COVID-19 shift ensures that nurses experience less heat during their work. The cooling vests offer such effective cooling that they are now part of the standard work clothing for nurses in the COVID nursing departments at Radboudumc.
Hermesdorf Prizes for COVID-19 research team and Charlotte Bekker7 January 2021
The entire COVID-19 research team at Radboudumc, which includes Frank van de Veerdonk, Mihai Netea, Roger Brüggemann, Leo Joosten and Alexander Hoischen, will receive the 2020 Hermesdorf Prize. Charlotte Bekker will be awarded the Hermesdorf Talent Prize.