HFSP Grant for Johannes Textor30 March 2020
Johannes Textor, theme Cancer development and immune defense, has been awarded a program grant of 1 million US dollars by The Human Frontier Science Program (HFSP) to investigate how T cells navigate extremely dense environments using experiments, modeling and methods from pedestrian dynamics.
Ritalin enhances your ability to do tasks by making you more motivated26 March 2020
A new study uncovers how stimulants like Ritalin work in the brain, and it challenges some misconceptions for its recreative use. The collaboration between Radboudumc and Brown University (USA) was published in the journal Science.
Dealing with COVID-19 in low- and middle-income countries26 March 2020
RIHS researcher Joost Hopman believes that low-and middle-income countries should intensify their preparedness for a possible COVID-19 outbreak. This was the core message of an opinion article that he wrote at the request of the medical journal JAMA.
Physiotherapy is important to the recovery of patients with the coronavirus26 March 2020
Patients who have been infected with the coronavirus and admitted to the hospital for this reason should receive physiotherapy as soon as their condition allows. This is the view expressed by physiotherapists and researchers from the Radboudumc in a set of joint treatment recommendations.
Healthcare utilization and regional variation of end-of-life hospital care in Dutch cancer patients26 March 2020
In International Journal of Quality Health Care RIHS researcher Femke Atsma showed high healthcare utilization and medical variation in End of Life care in Cancer patients, which was not associated with GP care or long term care.
Study into better protection for healthcare workers against coronavirus infection19 March 2020
Radboudumc and UMC Utrecht will investigate whether health care workers are better protected against the coronavirus after a vaccination against tuberculosis (BCG vaccine). This vaccine does not directly protect against the coronavirus, but provides a boost to the immune system.
Differences in the placental disposition of TNF inhibitors uncovered19 March 2020
In Clinical Pharmacology and Therapeutics, researchers from the Depts. of Pharmacology and Toxicology, Obstetrics and Gynecology, and Health Evidence, in collaboration with Sanquin Diagnostic Services, investigated the placental handling of the TNF inhibitors infliximab and etanercept.
The effect of pregnancy on the pharmacokinetics of dolutegravir in women living with HIV17 March 2020
In Clinical infectious diseases RIHS researchers Pauline Bollen, Jolien Freriksen, Angela Colbers and David Burger together with researchers of the PANNA network showed that dolutegravir use in pregnancy results in effective plasma concentrations.
Greater attention to sex and gender needed in healthcare13 March 2020
Scientific research shows that both sex and gender influence health behavior and impact disease development, having an effect on its diagnosis, treatment, and long-term effects as well. That is what RIHS researcher Sabine Oertelt-Prigione states in The Lancet EClinical Medicine.
Interleukin-37 plays a rol in the pathogenesis and treatment of gout11 March 2020
RIMLS researchers Leo Joosten, Viola Klück and Rosanne van Deuren, in collaboration with the Dept. of Human Genetics, discovered that rare genetic variants in interleukin-37 link the anti-inflammatory cytokine to the pathogenesis and treatment of gout.
NWO Open Competition ENW - KLEIN grant for Jenny van der Wijst9 March 2020
KLEIN grants offer researchers the possibility to realize curiosity-driven, fundamental research and elaborate creative and risky ideas. For this project, Jenny is seeking an enthusiastic postdoc to join her team working on ion channels.
FET-OPEN grant for Toin van Kuppevelt and Willeke Daamen6 March 2020
A grant of 592 kEuro has been awarded to Toin van Kuppevelt and Willeke Daamen, theme Reconstructive and regenerative medicine, for a Horizon 2020 FET-OPEN project entitled “Heparin and heparan sulphate: from sequence determination to therapeutic strategies for Parkinson’s disease”.
Electronic nose smells precursor of oesophageal cancer5 March 2020
A portable electronic nose can effectively detect precursors of oesophageal cancer, reported by RIHS researchers Yonne Peters and Peter Siersema in the medical science journal GUT. This was demonstrated in an initial study involving more than four hundred patients.
Prevention of tuberculosis among people with diabetes the first clinical trial globally5 March 2020
In recent years it has become clear that diabetes is an important factor driving the global tuberculosis epidemic. Diabetes also leads to more severe and recurrent disease and more TB deaths. The first clinical trial to prevent TB among people with diabetes will be started by the PROTID consortium.
Plugging the gap ZonMw/Health Holland grant3 March 2020
RIMLS en RIHS researchers Willeke Daamen, Frank Vandenbussche, Joris van Drongelen, Toin van Kuppevelt and Janneke Grutters have been granted 1.3 million euro for the development and evaluation of a new technology to prevent premature rupture of fetal membranes (iPPROM).
People-like-me treatment for intermittent claudication Personalized approach for patients27 February 2020
Radboudumc, with the University of Colorado, ClaudicatioNet and Harteraad, has developed a method to better treat people with intermittent claudication. This method, by RIHS researcher Thomas Hoogeboom among others, enables physiotherapists to coordinate the care process with the patient better.
Jurgen Fütterer appointed Professor of Image-Guided Oncological Interventions26 February 2020
RIHS researcher Fütterer is an interventional radiologist and an expert in the field of cancer imaging techniques, image-guided interventions and robotics. He is also Professor at the Robotics and Mechatronics Group at the University of Twente.
NWO open call GROOT grant for Michiel Vermeulen24 February 2020
Michiel Vermeulen, theme Cancer development and immune defense, received a 300,000 EUR grant within the NWO-GROOT consortium. He will use mass spectrometry-based proteomics and interaction proteomics applications to study proteome and gene expression dynamics during early C. Elegans development.
Dutch Brain Foundation grant for EENnacoma20 February 2020
Lavrijsen and Van Erp: ‘This grant will facilitate practice-based research, professionalization and further academization of EENnacoma, and links between different health care and research institutions all for the benefit of people with prolonged disorders of consciousness and their families.'
RIHS Awards Ceremony five winners19 February 2020
On 18 February the RIHS 'Koek & Zopie' event took place. In front of an audience of more than 125 colleagues, RIHS awardees accepted their awards for the best PhD thesis, the research product with the highest impact on society, the best peer-reviewed publication and the Supervisor of the year 2019.
Preserved specific force in facioscapulohumeral muscular dystrophy19 February 2020
DCMN researcher Saskia Lassche et al., theme Disorders of Movement, recently showed in Neurology that remaining muscle fibers in Facioscapulohumeral muscular dystrophy (FSHD) patients have normal muscle strength, even in severely affected muscles.
Researchers investigate how stem cells affect the immune system18 February 2020
RIMLS researchers Irma Joosten and Renate van der Molen, participating in an European study into the treatment of brain damage in premature babies. Is it possible to limit or even partly repair the damage with stem cells? They focus primarily on the effect of those stem cells on the immune system.
Five ZonMw ‘Off Road’ grants for Radboudumc researchers17 February 2020
Benoit Besson, Annemarie Boleij, Jonne Doorduin, Jorik Nonnekes and Sara Roig Merino have each received an ZonMw ‘Off Road’ grant of €100,000. The grants are intended for biomedical health researchers who dare to go off the beaten track in their search for new insights and unexpected breakthroughs.
Dutch Kidney Foundation PhD grant for Johan van der Vlag and Tom Nijenhuis14 February 2020
Johan van der Vlag and Tom Nijenhuis, theme Renal disorders, received this grant for their joint research project “Targeting a novel paracrine signaling pathway between glomerular endothelium and podocytes to treat glomerular injury”.
KNAW Early Career Award for Geert Litjens13 February 2020
Twelve young researchers received the Early Career Award from KNAW on 4 february. One of them is RIHS researcher Geert Litjens. The Award is aimed at researchers in the Netherlands at the start of their career who are capable of developing innovative and original research ideas.
Interactive career day for Postdocs and PhD candidates13 February 2020
45 Postdocs and PhD candidates attended the first Interactive career day organised by Janssen Pharmaceutica, to learn more about career perspectives and R&D activities that on the longer term can lead to ideas and potential future collaboration.
SPL Medical starts clinical trial with contrast agent ferrotran11 February 2020
SPL Medical is starting an international registration study for its contrast agent Ferrotran. The study is being conducted in ten hospitals in Germany, Switzerland and the Netherlands. RIHS researcher Jelle Barentsz discovered the value of this drug in patients with lymph node metastases.
Khondrion begins study on optimal dosage of new drug10 February 2020
Pharmaceutical company Khondrion, a spin-off from Radboudumc, has taken another important step in the development of its drug sonlicromanol. The first patients have used the drug as part of a phase 2b study, which focuses on determining the optimum dose and efficacy.
Human pDCs attract cytolytic lymphocytes in anti-cancer vaccination6 February 2020
RIMLS researchers Jasper van Beek and Jolanda de Vries, theme Cancer development and immune defense, discovered that pDCs can efficiently recruit cytolytic immune effector cells, a property that could be exploited in anti-cancer vaccines. They have published these findings in Cell Reports.
King Willem-Alexander meets up with Judith Wolf about the causes of doubling number of homeless people6 February 2020
King Willem-Alexander and State Secretary Paul Blokhuis of Health, Welfare and Sport (Ministry of VWS) paid a working visit to Weert on 21 January in the context of shelter for the homeless and day care. During his visit the King and State Secretary spoke with RIHS researcher Judith Wolf.
Research Integrity Round with Frank Miedema6 February 2020
Guest speaker on 9 March 2020 is Frank Miedema, Vice Rector for research and chair of the Utrecht University Open Science program. He is one of the initiators of Science in Transition. All students, PhD candidates and senior researchers are invited to attend. Please register via the website.
ZonMw funding for teams of Michiel Vermeulen and Jolanda de Vries4 February 2020
The awarded research projects of RIMLS researchers Michiel Vermeulen, Jolanda de Vries, Gerty Schreibelt and Martijn Verdoes and colleagues will initiate new research lines and collaborations between various research groups.
General practitioners rarely order images for back problems4 February 2020
8% Of all general practitioners regularly order imaging for patients who have lower-back pain without severe symptoms. Such imaging does not contribute to the treatment. This is indicated by the results from the Doen of Laten? project, a study conducted by Radboudumc, the LUMC and VGZ Cooperation.
New Guidelines for the detection of prostate cancer MRI instead of tissue samples3 February 2020
The module on diagnostic prostate MRI for the NVU guidelines for prostate carcinoma took effect on 29 January 2020. The development of these guidelines is due in part to the efforts of RIHS researcher Jelle Barentsz and Ivo Schoots (Erasmus MC).