News Research

Sensitive blood-test as patient-friendly alternative for bone marrow-based cancer monitoring

Hans Jacobs and Pieter Langerhorst, theme Cancer development and immune defense, and colleagues are one step closer to implementation of personalized diagnostics for bone marrow-based cancer monitoring.

Register for peer coaching for RIMLS PhD candidates

As a PhD candidate, you are in the lead of your own learning process. But you don’t need to do this alone: Register for the peer-coaching group ‘Stay in the lead – Together’ before 11 November 2021.

Frans Russel appointed member Supervisory Committee of RIVM

Frans Russel, theme Renal disorders, has been appointed by The Minister of Health, Welfare and Sport (VWS).

Often additional demand for care without decreasing number of admissions Telemonitoring in chronic heart failure not unqualifiedly positive

To contain rising healthcare costs, digitization of healthcare is often seen as a solution. Researchers at the Radboudumc examined the use of telemonitoring in chronic heart failure. Does this reduce hospital admissions and visits to the emergency room?

RIMLS awards call for nominations

RIMLS awards several prizes to stimulate and honor our (young) researchers. Please find here an overview of the upcoming awards. Deadline 24 November 2021.

Epigenetics: Immunization is passed on to offspring Mice transmit adaptations to infections to next generations

Does an infection affect the immunization of subsequent generations? It does, according to research now published in Nature Immunology.

Why we are curious about 'useless' information A neurocognitive explanation

In our daily lives, we are exposed to an overload of information. We found ourselves to be curious about both 'useful' information such as weather forecasts, and 'useless' information such as the infinite content on social media. A new study provides us a cognitive explanation to such curiosity.

Doubling of depression in pregnant women during corona lockdown

Worries about the virus and reduced support from healthcare and social network contribute to mental health problems

More frequent genetic testing required in children with language delays

Genetic cause for developmental language and speech disorder in child provides relief for parents. Lot Snijders Blok describes errors in five new genes.

Palliative care for people with Parkinson’s Disease and their family Caregivers Current state of affairs

Advanced stage Parkinson’s disease can cause a variety of symptoms, for which palliative care can be beneficial, though research from the point of view of patients in later stages is still rare. Radboudumc researchers therefore placed their patients perspectives at the center of their recent study.

Genetic mutations cause severe magnesium deficiency

Newly discovered errors in DNA change diagnostics and treatment. Jeroen de Baaij tracked down new genetic errors that cause magnesium deficiency and published the findings in the Journal of the American Society of Nephrology.

AI helps the defibrillator think

In the future, the AED and the defibrillator will be able to do more than they do today. Now the devices can only give patients who need to be resuscitated a shock, but in time it will be possible, with the help of artificial intelligence, to say more about the condition of the patient.

Tom Nijenhuis appointed professor of Rare Kidney Diseases

Wanted: RIMLS PhDs to organize ENABLE symposium in Seville in November 2022

Ever thought it could be fun to organize a scientific symposium? Want to improve your CV? Want to collaborate with international PhD candidates? Want to get in contact with biomedical companies? Ever felt lost at a conference because of too little focus on young researchers?

Best presentation award for Felicitas Pardow at the European Epidermal Barrier Research Network

During the annual meeting of the European Epidermal Barrier Research Network (E2BRN) recently, Felicitas Pardow received the best presentation award.

Antibodies are sustained in nasal fluid after mild corona infection

Testing through nasal fluids is easier than through blood

Large AI project receives over €95 million for ten years of public-private research

The Dutch Research Council (NWO) is to fund two consortia for a period of ten years. Radboudumc participates in the ROBUST consortium, which consists of 17 AI labs, eight of which are dedicated to healthcare. Radboudumc leads five of these eight labs.

Reading ADP-ribosylation signaling using chemical biology and interaction proteomics published in Molecular Cell

Kasia Kliza and Michiel Vermeulen worked on a project to synthesize biotinylated ADPr-based probes that can identify ADPr readers and determine their specificity for mono- and polyADPr. They published this in Molecular Cell.

Systematic analysis of short tandem repeats in 38,095 exomes provides an additional diagnostic yield

Christian Gilissen and colleagues published in Genetics in Medicine about their work guiding the application of short tandem repeat analysis in clinical exome sequencing.

TropIQ seeks new mosquito repellents

TropIQ Health Sciences, a Radboudumc spin-off, has received a 1.3 million USD grant from the Bill & Melinda Gates Foundation to track down new mosquito repellents.

New start-up Patholyt will bring AI research into pathology diagnostics

Patholyt is on a mission to accelerate the adoption of artificial intelligence in pathology diagnostics and improve the chances of cancer patients worldwide. Patholyt is a spin-off from Radboudumc, a frontrunner in computational pathology research.

Treatment of most common skin cancer can sometimes wait

Not treating but keeping an eye on the cancer is also an option

Donor limbs last longer thanks to improved preservation technology

Research by Anne Sophie supported Maartje's double hand transplantation

Young Radboudumc researchers receive grant to engage in bio-medical and health research that is off the beaten path

The ZonMw Off Road program is once again giving young scientists the opportunity to conduct innovative research in medical and/or health care. This research is off the beaten track and aims to bring about new insights and unexpected breakthroughs for healthcare and healthcare innovation.

Infections increase risk to develop dementia

In a recently published study, Radboudumc researchers investigated the effects of infectious events on cognitive decline and the development of dementia and its possible structural underpinning using pre- and post-infection MRI of the brain.

Young Investigator Award for Alex Garanto

Alex Garanto has been honored with the 2021 Mary Ann Liebert, Inc. publishers Young Investigator Award

Depressive symptoms during pregnancy affect baby

Depression or depressive symptoms during pregnancy may lead to a bad start for the infant, such as a preterm birth. Researchers of Radboudumc found that this was true for both women who were treated with antidepressants and those who received no medication.

ENABLECARES launches a course on entrepreneurship for PhD candidates and postdocs

Are you thinking about what to do after your PhD? Want to know more about entrepreneurship? This course gives you insight in many aspects of entrepreneurship and research in industry.

Effectiveness and predictors of response to somatostatin analogues in patients with gastrointestinal angiodysplasias

Lia Goltstein and colleagues published a study about effectiveness and predictors of response to somatostatin analogues in patients with gastrointestinal angiodysplasias: a systematic review and individual patient data meta-analysis.

Study shows no relation between breastfeeding and inhibitory control in three-year-old children

New study from Radboudumc researchers, investigated whether breastfeeding was related to inhibitory control, the ability to control impulsive behavior, of 3-year-old children, and whether diet played an intermediate role in this relation.

Increasing stress resilience through neurofeedback training

Stress-related mental illnesses are amongst those with the highest disease burden, and efforts to reduce their prevalence have remained largely unsuccessful. A recent study from Florian Krause and colleagues investigated the possibility of regulating your brain networks away from a “stressed” state.

Cooperating T cells clear tumor cells more effectively

Live imaging: immune cells attack tumor

Two million euros for improved treatment and outcomes of COVID-19 in the elderly

ZonMw awarded a grant of nearly two million euros to a large group of researchers to improve the outcomes of elderly people with COVID-19. The study, in which the Radboudumc also participates, provides insight into the course and treatment of COVID-19 in the elderly.

Genetic archaeology reveals major changes in the immune system

Evolution of the immune system unraveled based on ancient DNA

People with Parkinson’s disease can benefit from seven gait strategies

People with Parkinson’s disease who have difficulty walking can use several strategies to improve walking. New research shows that many people have never heard of or tried these strategies.

Consortium grant Dutch Kidney Foundation for ArtDECO consortium

The Dutch Kidney Foundation awarded a consortium grant of 1.5M euros to the ArtDECO consortium, >400K euros of which will be allocated to the Radboudumc and more specifically to the AGORA data- and biobank.

Tackling cancer with radioactive particles

Professor Sandra Heskamp receives grant for research into cancer treatment with radioactivity

Three groundbreaking Radboud projects launched through NWO open competition

Three groundbreaking research projects at Radboudumc and Radboud University have been awarded grants of up to 50,000 euros through NWO's ENW - XS Open Competition.

New Frontiers symposium on Translational Glycoscience Last chance for early bird registration

Register now for our annual New Frontiers Symposium (18 & 19 November 2021) on current advances in glycobiology.

Unraveling piRNA-mediated degradation of viral RNA in vector mosquitoes published in Nucleic Acids Research

Joep Joosten and colleagues have published their discoveries about a new molecular mechanism with important implications for our understanding of the mosquito immune system and its role in controlling transmission of viruses.

Photosensitizer-based multimodal PSMA-targeting ligands for intraoperative detection of prostate cancer

Sandra Heskamp and Yvonne Derks published in Theranostics that photosensitizer-based PSMA-targeting ligands can be used for intraoperative detection and treatment of prostate cancer.

Genetic diagnosis in hereditary hemochromatosis discovering and understanding the biological relevance of variants

Floor Baas and Dorine Swinkels, theme Renal Disorders, published about assessment of pathogenicity of genetic variants in hereditary hemochromatosis.

A single comprehensive DNA test of a tumor is usually sufficient

A one-time measurement of the entire tumor DNA is almost always sufficient to find all DNA errors that are important for treatment.

Fresh postdoc wanted for RIMLS Graduate School committee

Do you want to use your experience as a RIMLS PhD candidate for the next generation?

Call for Research at InScience Filmfestival Register before 16 September 2021

ENABLE continues New funding guarantees four more international conferences by and for young researchers

Thanks to sponsoring of FEBS (Federation of European Biochemical Societies) and IUBMB (International Union of Biochemistry and Molecular Biology), ENABLE’s success formula can be continued for four more years. That means: four more gatherings full of science, career options, outreach and fun.

Off the shelf proximity biotinylation for interaction proteomics

Irene Santos-Barriopedro and Michiel Vermeulen, theme Cancer development and immune defense, published an off-the-shelf proximity biotinylation enzyme for interaction proteomics.

Fewer gallbladder surgeries do not reduce pain symptoms

A third of patients still have symptoms a year after a gallbladder removal. Dutch research in JAMA Surgery shows how patient and surgeon can make a better choice.

KNAW Ter Meulen grants for Radboudumc researchers

Four young researchers of the Radboudumc in the field of pediatrics and related fields can go abroad for a scientific research project/work visit in the coming year with a KNAW Ter Meulen grant.

Radboudumc to lead research team into tackling future pandemics NWO funds complexity research on pandemics

The Radboudumc is going to lead a study on how to deal with future pandemics, together with Radboud University and the University of Amsterdam. Rick Quax from the Informatics Institute/IAS is involved in this project.