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About
Who we are
At the Radboudumc Technology Center Bioinformatics we believe that computational biology and big data solutions are key in shaping the data-driven healthcare of the future. We provide complete data analysis solutions, give access to state-of-the-art bioinformatics methods and to the expertise and capabilities of Radboudumc’s bioinformatics community. The RTC is a one-stop-shop for biodata analysis with rapid deployment, with no sacrifices on data safety and privacy, to contribute to Radboudumc’s mission to have a significant impact on healthcare.
Our goals
- Provide bioinformatics advice, tools, infrastructure and services with clear price structures
- Arrange user groups, courses, network events and expert meetings to bolster interaction
- Enhance research and diagnostics through synergy, specialization and collaborations
- Leverage expertise to create opportunities and funding for clients and consortia’s
- Implement data and software standards for better safety, reproducibility and scaling
Services & expertise
What is bioinformatics
Bioinformatics combines expertise from many scientific disciplines, and concerns the processing and analyzing of large amounts of bio-data using computational methodologies.
read moreHOPE User-friendly web service
HOPE analyzes the structural effects of a point mutation in a protein sequence. Input your protein sequence and the mutation and HOPE will collect and combine available information from a series of web services and databases and will produce a report, complete with results, figures and animations.
visit website
Our analysis services and solutions
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- Comprehensive QC and MultiQC reports
- UMI demultiplexing
- Differential Gene Expression Analysis
- Pathway analysis and Annotation
- PacBio Iso-Seq and Isoform Classification
- Publication-grade R graphics and plots
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- Advanced and automated QC
- Single Cell RNA Seq analysis based on Seurat and 10X
- Cluster based Differential Gene Expression Analysis
- Cell-Cell communication using CellChat
- Bulk RNA Seq Deconvolution based on Single Cell data
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- Single Nucleotide and Structural Variant calling and annotation
- Genome assembly, annotation and visualization
- Comparative Genomics and Phylogenetics
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- Complete tumor analysis based on Hartwig Medical Foundation pipeline
- Tumor and metastasis evolution and phylogenetics using Conipher
- CNV and Somatic Variant Annotation
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- Analysis of 3D-structures and complexes
- Protein homology modeling and function prediction
- Alphafold implementation and analysis
- Variant effect prediction using 3D-structures
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- Comparative Genomics
- Whole Genome Sequencing
- Phylogenomics
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- Metagenome assembly
- Taxonomy and Gene Function classification and annotation
- Metatranscriptomics
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- Marker Gene Sequencing (16S, 18S, ITS)
- Single Locus Sequence Typing
- Identifying antibiotics resistance, virulence factors
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- Linux and HPC support
- Ontology and Text mining
- Data management
- Uploading to Repository
- Data analysis automation and upscaling
Organization and people
Getting here
Visiting address
Geert Grooteplein 28
6525 GA Nijmegen
Directions
Our experts
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Sander Bervoets Lead Product Owner
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Tom Ederveen postdoc
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Alem Gusinac data-analist Pathologie
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Youkyung Lim data-analist Medical BioSciences
