The following news items are related to the research Infectious diseases and global health.
RIMLS 25 years jubilee festival The Future is Yesterday3 October 2019
Together with more than 250 colleagues and alumni we celebrated 25 years of research into the molecular mechanisms of disease. During this exciting and informal event, we not only took a trip down memory lane, but also looked ahead to the next 25 years and beyond…...
Radboud-led collaboration generates innovative candidate drug against malaria19 September 2019
A molecule once designed to cure the skin disease psoriasis appears to be particularly effective against malaria. The antimalarial properties were revealed thanks to one researcher’s inspired hunch when the psoriasis drug discovery programme came to a dead end.
Radboud study on Dirty Money wins Ig Nobel Prize17 September 2019
By shaking hands we are exchanging bacteria. Does this happen without direct hand-to-hand contact, for example when paying with paper money? Andreas Voss, clinical microbiologist at Radboudumc and CWZ, and colleagues in the United States received an Ig Nobel Prize for research into dirty money.
Four Veni grants for junior RIMLS researchers22 July 2019
Four junior researchers, affiliated to the RIMLS, have each received a Veni grant of 250,000 Euro from NWO. Our researchers received this prestigious grant for their remarkable and original talent and their ability to carry out innovative research.
4,8 million euros for prevention of tuberculosis among people with diabetes in Africa16 July 2019
Reinout van Crevel and Lindsey te Brake have received European funding of 4.8 million euros to lead an international consortium to screen thousands of people with diabetes in Uganda and Tanzania for TB, and investigate the effect and costs of 3 months preventive treatment for TB.
Exome sequencing in routine diagnostics: a generic test for 254 patients with primary immunodeficiencies18 June 2019
Exome sequencing may provide a genetic diagnosis in a significant number of patients in a single genetic test. Alexander Hoischen and Mihai Netea, theme Infectious diseases and global health, and colleagues, published their results in Genome Medicine.
Developing malaria gametocytes under attack6 June 2019
In Science Translational Medicine, researchers from the group of Teun Bousema and international colleagues have revealed previously unknown targets of natural human antibody responses that are found on the surfaces of red blood cells infected with malaria parasites.
The XN-30 hematology analyzer for rapid sensitive detection of malaria a diagnostic accuracy study6 June 2019
In BMC Medicine Annelies Post, Berenger Kaboré, Isaie Reuling and colleagues described a new method of malaria detection using whole blood: the XN-30 is a new hematology analyzer which simultaneously provides a complete blood count and quantification of malaria parasitemia, allowing rapid treatment.
Three VIDI grants for RIMLS researchers24 May 2019
Matthijs Jore, Daniele Tauriello and Johannes Textor are each to receive up to 800,000 euros to develop an innovative research theme and to build up their own research group. NWO is awarding the Vidi grant as part of the Innovational Research Incentives Scheme.
Minocycline to treat pulmonary Mycobacterium avium complex disease9 May 2019
In Journal of Antimicrobial Chemotherapy Mike Ruth, Jakko van Ingen and colleagues showed that minocycline may be useful to treat pulmonary diseases caused by Mycobacterium avium complex bacteria. This is important as few drugs are active against this disease and treatment outcomes are very poor.
Removal of sialic acid from platelets responsible for thrombocytopenia in dengue23 April 2019
In the PLoS Pathogens Quirijn de Mast and his colleagues showed that excessive binding of the coagulation protein von Willebrand factor leads to removal of sialic acid from platelets and platelet clearance.
Nontuberculous mycobacteria and fungal co-infections Bonnie and Clyde?18 April 2019
In The European respiratory journal Jakko van Ingen and Sanne Zweijpfenning showed that 40% of patients diagnosed with nontuberculous mycobacterial pulmonary disease also meet diagnostic criteria for chronic pulmonary aspergillosis.
Interacting non-specific immunological effects of BCG and Tdapf vaccinations5 April 2019
In a randomized trial Mihai Netea and colleagues aim to investigate the non-specific immunological effects of BCG and DTP-containing vaccines on the immune response to unrelated pathogens. They have published their findings in Clinical Infectious Diseases.
Impulsivity and infectious diseases among female prisoners in Indonesia Knowledge transfer alone not sufficient for controlling infectious diseases28 March 2019
Unprotected sexual contact and intravenous drug use are important routes of infection for infectious diseases such as HIV, hepatitis B and C and syphilis.
Importance of prospective studies in pregnant and breastfeeding women living with HIV14 March 2019
In Clinical Infectious Diseases Angela Colbers, Stein Schalkwijk and David Burger give considerations on how to effectively evaluate aspects of clinical pharmacology required for safe and effective treatment to optimize pharmacotherapy during pregnancy and breastfeeding.
Effect of prolonged antibiotic treatment on cognition in patients with Lyme borreliosis5 March 2019
In Neurology Anneleen Berende, Roy Kessels, Bart-Jan Kullberg and colleagues showed that longer-term antibiotic treatment did not lead to better cognitive performance compared to a 2-week regimen in patients with Lyme disease-attributed persistent symptoms.
15 million Euro to identify new drug targets for HIV28 February 2019
André van der Ven and Mihai Netea, theme Infectious diseases and global health, and colleagues, will receive 15 million Euro from pharmaceutical company ViiV Healthcare for research into new ways to fight the HIV virus. The aim of the HIV 2000+ project is to identify new drug targets for HIV.
ZonMw TOP grant to uncover the dormancy of malaria parasites7 February 2019
Richard Bartfai, theme Infectious diseases and global health, and Clemens Kocken (BPRC) received 675,000 euros from ZonMw to uncover the molecular mechanisms underlying dormancy of malaria parasites, a major obstacle to efficient treatment of P. vivax malaria.
KNAW Ammodo Award for Teun Bousema1 February 2019
Each of the laureates of this prestigious award for top researchers in the Netherlands receive a monetary prize of 300,000 euro. The funds can be used to explore new directions in pure scientific research. Bousema is one of the eight laureates of 2019.
A personal touch of Febrina Meutiawati20 January 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Febrina Meutiawati.
LEO Foundation grant for Ellen van den Bogaard and Patrick Zeeuwen17 January 2019
LEO Foundation ‘Open competition grants’ are given to support the best dermatology research projects worldwide that improve the understanding of the underlying medicinal, biological, chemical, or pharmacological mechanisms of dermatological diseases and their symptoms.