Our purpose
This program aims to identify mechanisms of therapy resistance in model systems.
Goals
- Identifying mechanisms of therapy resistance in model systems.
- Exploiting molecular knowledge to overcoming therapy resistance in vitro, in preclinical models, in silico.
- Clinically relevant improved targeting strategies and precision medicine.
- Collective processes in tumor biology and immune defense.
- In vivo registration and repurposing molecular reporters across tissue types and disease models.
- Understanding and targeting fibrosis.
- 3D models and targeting of the myofiber compartment.
- Reactive oxygen species-(ROS-) targeted therapies.
Research group leaders
See which research group leaders (RGLs) contribute to this research program.
read moreResearch group leaders
Our programs form inspiring environments in which research groups work together toward a common and clear goal, enabling our researchers to strenghten collaboration and cross thematic and disciplinary boundaries. Within and outside Radboudumc.
RGLs contributing to this research program
- Jeroen de Baaij
- Roland Brock
- Peter Friedl
- Johannes Textor
- Martijn Verdoes
- Nielka van Erp
- Sandra Heskamp
- Carla van Herpen
- Niven Mehra
- Jack Schalken
- Paul Span
- Annemiek van Spriel
In the near future, we plan to link specially designed research group pages instead of these profile pages.