Research Research programs 3D biology and disease mechanisms

Our purpose

This program aims to identify mechanisms of therapy resistance in model systems.


Goals

See some of the most important goals for this research program.

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Goals

  • Identifying mechanisms of therapy resistance in model systems.
  • Exploiting molecular knowledge to overcoming therapy resistance in vitro, in preclinical models, in silico.
  • Clinically relevant improved targeting strategies and precision medicine.
  • Collective processes in tumor biology and immune defense.
  • In vivo registration and repurposing molecular reporters across tissue types and disease models.
  • Understanding and targeting fibrosis.
  • 3D models and  targeting of the myofiber compartment.
  • Reactive oxygen species-(ROS-) targeted therapies.



Research group leaders

See which research group leaders (RGLs) contribute to this research program.

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Research group leaders

Our programs form inspiring environments in which research groups work together toward a common and clear goal, enabling our researchers to strenghten collaboration and cross thematic and disciplinary boundaries. Within and outside Radboudumc.

RGLs contributing to this research program

In the near future, we plan to link specially designed research group pages instead of these profile pages.



Spokesperson

prof. dr. Alessandra Cambi

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Spokesperson

prof. dr. Peter Friedl

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Spokesperson

prof. dr. Jack Schalken

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