3D biology and disease mechanisms

Aims

• Identifying mechanisms of therapy resistance in model systems.
• Exploiting molecular knowledge to overcoming therapy resistance in vitro, in preclinical models, in silico.
• Clinically relevant improved targeting strategies and precision medicine.
• Collective processes in tumor biology and immune defense.
• In vivo registration and repurposing molecular reporters across tissue types and disease models.
• Understanding and targeting fibrosis.
• 3D models and  targeting of the myofiber compartment.
• Reactive oxygen species-(ROS-) targeted therapies.