Transfer of new anti-hepatitis C drugs across the human placenta9 September 2020
In a recent publication in American Journal of Obstetrics and Gynecology, researchers from the Departments of Pharmacology and Toxicology, Pharmacy, Obstetrics and Gynecology, Gastroenterology and Hepatology, investigated the placental passage of two such drugs for the first time.
Safer and more effective use of medicines in children How 'virtual children' will make a difference31 August 2020
The efficacy and safety of about half of all drugs prescribed to children has not been adequately researched. Because growth and development change the way a child's body deals with drugs, it runs an increased risk of receiving ineffective or unsafe drugs.
Molecular scissors play a role in kidney and lung leakage in COVID-19 patients18 June 2020
‘Molecular scissors', play a role in leakage of fluid from blood vessels to lungs and kidneys in COVID-19 patients. The scissors cut the protective sugar layer in the blood vessels. The more serious the disease, the more active the scissors, wrote Johan van der Vlag and colleagues in MedRxiv.
New insight into the effect of hydroxychloroquine undermines its use in corona11 June 2020
Researchers at Radboud university medical center have discovered an as yet unknown effect of hydroxychloroquine. Raphael Duivenvoorden was interviewed in the program Op1 at NPO1 to elaborate on the findings. It seems unlikely that chloroquine has beneficial effect in corona infections.
Johan van der Vlag appointed as professor of Immunology of Kidney Diseases and Transplantation23 April 2020
Johan van der Vlag is an expert in unravelling the molecular and immunological mechanisms underlying kidney disease and transplantation. His research stems from clinical questions and focuses on the development of new diagnostic/prognostic and therapeutic strategies.
Gene controls the formation of photosensitive disks in retinal cells21 April 2020
Researchers have unraveled a molecular mechanism that regulates the build-up of the photosensitive segments in the cones and rods in the retina. A protein PCARE, controls this process. These new insights, published in PNAS USA, could make a significant contribution to new therapies for eye diseases.
NWO Open Competition ENW - KLEIN grant for Jenny van der Wijst9 March 2020
KLEIN grants offer researchers the possibility to realize curiosity-driven, fundamental research and elaborate creative and risky ideas. For this project, Jenny is seeking an enthusiastic postdoc to join her team working on ion channels.
Dutch Kidney Foundation PhD grant for Johan van der Vlag and Tom Nijenhuis14 February 2020
Johan van der Vlag and Tom Nijenhuis, theme Renal disorders, received this grant for their joint research project “Targeting a novel paracrine signaling pathway between glomerular endothelium and podocytes to treat glomerular injury”.
RIMLS PhD retreat registration is open23 January 2020
Yearly, RIMLS PhD candidates gather for the two-day PhD Retreat. Apart from the science, this event is highly valued for the opportunity to meet and get to know fellow PhD candidates during the social activities. Early bird registration and abstract submission deadline: 4 March 2020.
NWO Open Competition Domain Science - XS grant for Ronald van Rij and Jenny van der Wijst21 January 2020
NWO Domain Science has awarded Ronald van Rij, theme Infectious diseases and global health and Jennny van der Wijst, theme Renal disorders an XS grant. The XS category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea.
Rubicon Grant for Sami Mohammed14 January 2020
Former RIMLS researcher Sami Mohammed, theme Renal disorders, received a Rubicon Grant from the Dutch Organisation for Scientific Research (NWO). The Rubicon program gives young, highly promising researchers the opportunity to gain international research experience.
Kolff grants Dutch Kidney Foundation for Raphaël Duivenvoorden and Jitske Jansen17 December 2019
The Dutch Kidney Foundation supports talented postdocs and physician researchers through providing personal grants that support different phases of a research career. This year Raphaël Duivenvoorden and Jitske Jansen, theme Renal disorders, received a Kolff grant.
A personal touch of Marlies Cornelissen31 October 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Marlies Cornelissen.
X² Ambition Award for Sandra Heskamp28 October 2019
This award is intended for 'coming women’: young, ambitious women at a stage of their careers where they make important career choices. This prize is especially for women who show exemplary behaviour within the organization where they work, but also outside their organization.
KWF Roadshow 11 November 201910 October 2019
In which way(s) can KWF provide optimal support to oncological research and care? How can we maximize impact on our investments? These questions are pivotal in Ambition 2030: the vision that KWF developed in close cooperation with stakeholders in the oncological field.
Dorine Swinkels collaborates with winners of the Nobel Prize in Physiology or Medicine9 October 2019
The Nobel Prize in Physiology or Medicine 2019 was awarded jointly to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza for their discoveries of how cells sense and adapt to oxygen availability.
Scaling up nanotherapy7 October 2019
Scaling up and translating nanotherapy from pre-clinical work in small animal models to a clinical application is not trivial. Raphael Duivenvoorden, theme Renal disorders, and colleagues, published their results on translating a new nanoimmunotherapy in the journal Science Translational Medicine.
RIMLS 25 years jubilee festival The Future is Yesterday3 October 2019
Together with more than 250 colleagues and alumni we celebrated 25 years of research into the molecular mechanisms of disease. During this exciting and informal event, we not only took a trip down memory lane, but also looked ahead to the next 25 years and beyond…...
A personal touch of Juan Pablo Rigalli26 September 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Juan Pablo Rigalli.
Artificial intelligence for renal tissue assessment16 September 2019
Meyke Hermsen and Jeroen van der Laak, present an alternative approach, featuring a convolutional neural network for multi-class segmentation of periodic acid–Schiff-stained kidney tissue sections. Their work was published in the Journal of the American Society of Nephrology.
University Teaching Prize for Joost Hoenderop26 August 2019
The prize is a reward for excellent teaching and consists of a certificate and a sum of €3000, two-thirds of which is to be spent on educational activities. The prize was awarded on Monday 2 September when the 2019-2020 Academic Year was opened.
Four Veni grants for junior RIMLS researchers22 July 2019
Four junior researchers, affiliated to the RIMLS, have each received a Veni grant of 250,000 Euro from NWO. Our researchers received this prestigious grant for their remarkable and original talent and their ability to carry out innovative research.
Radboudumc Master Prize for Mark van Goor18 June 2019
Mark van Goor, theme Renal disorders, received the Radboudumc Master Prize for his MSc thesis entitled “High-resolution structure of the renal calcium channel TRPV5 revealed with cryo-EM”, which was based on his internship at the lab of Prof. Yifan Cheng, USA.
A personal touch of Johan van der Vlag13 June 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Johan van der Vlag.
Special microscope films how gateway in kidney cells opens and closes6 May 2019
One of the gateways in the kidney cell virtually exclusively allows calcium through. But how does that calcium channel work exactly? What does the molecular machine look like that makes sure that the channel opens and closes?
Lanreotide reduces liver and kidney growth in patients with polycystic liver disease29 April 2019
Joost Drenth, theme Renal disorders, made use of data from an open-label, randomized trial to determine the effects of lanreotide on height-adjusted liver volume and combined height-adjusted liver and kidney volume in patients with ADPKD. They have published their findings in Gastroenterology.