31 January 2019

In Gastroenterology Peter Siersema described the currently used treatment modalities for complex esophageal strictures, based on underlying cause and symptom duration, but also focusing on future treatment perspectives.

Benign esophageal strictures are frequently seen in clinical practice. Benign esophageal strictures are caused by a variety of esophageal disorders, including radiotherapy-induced and caustic injuries, eosinophilic esophagitis, and strictures after surgical resection for esophageal cancer. 
Most endoscopic resection esophageal strictures can be treated by endoscopic dilation, but a minority are found to be refractory or recurring after several dilation sessions. For these complex strictures, additional treatment modalities have become available, including endoscopic incisional therapy  and stent placement, which can be selected on the basis of symptom duration and underlying cause.
This article presents a stepwise algorithm for the clinical management of patients with benign esophageal strictures, including a rational use of currently available treatment modalities. 

Peter Siersema is member of theme Tumors of the digestive tract.
  • Want to know more about these subjects? Click on the buttons below for more news.


Related news items

Electronic nose smells precursor of oesophageal cancer

5 March 2020 A portable electronic nose can effectively detect precursors of oesophageal cancer, reported by RIHS researchers Yonne Peters and Peter Siersema in the medical science journal GUT. This was demonstrated in an initial study involving more than four hundred patients. read more

Mohrmann Stipend for Bakker and Peters

12 December 2019 Tuesday 10 December, Esmée Bakker and Yonne Peters were awarded a Christine Mohrmann stipend. The grant – 5000 euros each – gives them an opportunity to spend time at another university, preferably one abroad. read more

Electronic nose detects bacterium that can cause stomach cancer

10 September 2019 OP Oost promotes innovative cooperation between companies and research institutions. read more

Barrett oesophagus

6 June 2019 In Nature Reviews Disease Primers Yonne Peters and Ali Al-Kaabi provided a global overview of Barrett oesophagus and outlined key open research questions. This primer covered epidemiology, disease mechanism, diagnose, screening, prevention, management, and quality of life. read more

Low risk of progression in persistent non-dysplastic Barrett’s esophagus

19 September 2018 In Clinical Gastroenterology and Hepatology Peter Siersema and Yonne Peters showed that patients with stable persistence of non-dysplastic Barrett’s esophagus have a low risk of malignant progression and may not benefit from routine endoscopic surveillance. read more

Ayla Turan jury and audience award winner Radboud Talks 2018

18 April 2018 Watch Ayla's pitch about the prevention of bleedings after the removal of polyps in the intestines. read more