23 May 2019

Jeroen de Baaij, theme Renal disorders, was awarded with an Innovation Grant of the Dutch Kidney Foundation (Nierstichting). Jeroen's research proposal 'The HNF1B switch: Single-cell RNA sequencing to unravel renal cyst formation in ADTKD-HNF1B' was selected from a competitive field of innovative approaches to treat kidney disease.

Jeroen de Baaij

The project aims to understand renal cyst formation in patients with autosomal dominant tubulointerstitial kidney disease. This rare disease is caused by mutations in the HNF1B gene. Patients suffer from renal cysts, hypomagnesemia and diabetes. In the kidneys of these patients some cells form renal cysts, whereas other cells don’t. This project aims to decipher which mechanisms drive cells into cyst formation. By applying the innovative single-cell RNA-seq technique on renal cells, it will be possible to identify the mechanisms of renal cyst formation.
The Dutch Kidney Foundation aims to stimulate the quality of the renal scientific field in the Netherlands through providing grants that support innovation in the Netherlands. The program establishes stronger links between innovative research and patient care. By providing better understanding of cyst formation, the ultimate goal of improving treatment of patients with tubulointerstitial kidney disease may come one step closer.

Related news items

Bart van de Warrenburg appointed visiting professor at the UKM Medical Centre in Kuala Lumpur

11 November 2019

Neurologist and Principal Investigator at the Donders Institute Bart van de Warrenburg has been appointed visiting professor at the UKM Medical Centre in Kuala Lumpur.

read more

KNAW Van Leersum beurs for Mohammad Alsady

7 November 2019

Mohammad Alsady, theme Disorders of movement, received the “KNAW Van Leersum beurs”.

read more

3D breast ultrasound elastography to improve breast cancer detection

5 November 2019

One out of seven women will be diagnosed with breast cancer during their life. Early detection of breast cancer is important to increase the survival rate. Gijs Hendriks graduated recently on a new technique, 3D elastography, to detect breast cancer better.

read more

Self-management rehabilitation program improves participation in patients with neuromuscular disease

4 November 2019

Yvonne Veenhuizen, Alexander Geurts theme Neurorehabilitation, Baziel van Engelen, theme Disorders of movement, and colleagues, showed that Energetic improves participation in patients with neuromuscular disease. They have published their results in Neurology.

read more

New NFU eBROK® course open for registration

1 November 2019

This platform is not only for researchers who want to obtain their BROK® certificate, but also for researchers who already have a BROK® certificate and want to keep their certification (re-certification).

read more

Emily Klooster wins the NVZF incentive prize

31 October 2019

For the second year in a row, a PhD candidate from the Allied Health Sciences group of IQ Healthcare (RIHS), has won the "Dutch Association for Physiotherapists in the Hospital" incentive prize.

read more