About our equipmentRadionuclide imaging, including single-photon emission computed tomography (SPECT) and positron emission tomography (PET), relies on the tracer principle in which a minute amount of a radioactive tracer is injected into the body to monitor a physiological/biochemical process. By combining these imaging with an x-ray Computed Tomography (CT), the images acquired with both devices can be aquired sequentially, in the same session. Thus, functional imaging obtained by PET or SPECT, which depicts the spatial distribution of metabolic or biochemical process, can be aligned with anatomic imaging obtained by CT scanning.
At PRIME a wide series of Tc-99m, In-111, I-125, I-123 labeled probes are used for SPECT. PET probes labeled with F-18, Ga-68, Zr-89 and I-124 are produced.
Applications in PRIME
The PET/CT and SPECT/CT scanners in PRIME can be used for the following applications in mice and rats:
- imaging metabolic/biochemical processes;
- imaging receptor expression;
- imaging gene expression;
- imaging in vivo migration of cells.
The CT scanner (i.e. without PET or SPECT) can be used for the following applications in mice and rats:
- high resolution (20-40 µm) focused CT scans;
- medium resolution (140-200 µm) whole body CT scans;
- bone density measurements.