Research Facilities Radionuclide imaging

About our equipment

Radionuclide imaging relies on the tracer principle in which a minute amount of a radioactive tracer is injected into the body to monitor a physiological/biochemical process

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About our equipment

Radionuclide imaging, including single-photon emission computed tomography (SPECT) and positron emission tomography (PET), relies on the tracer principle in which a minute amount of a radioactive tracer is injected into the body to monitor a physiological/biochemical process. By combining these imaging with an x-ray Computed Tomography (CT), the images acquired with both devices can be aquired sequentially, in the same session. Thus, functional imaging obtained by PET or SPECT, which depicts the spatial distribution of metabolic or biochemical process, can be aligned with anatomic imaging obtained by CT scanning.

At PRIME a wide series of Tc-99m, In-111, I-125, I-123 labeled probes are used for SPECT. PET probes labeled with F-18, Ga-68, Zr-89 and I-124 are produced.

Applications in PRIME

Our PET/CT equipment can be used for several applications in mice and rats.

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Applications in PRIME

The PET/CT and SPECT/CT scanners in PRIME can be used for the following applications in mice and rats:

  • imaging metabolic/biochemical processes;
  • imaging receptor expression;
  • imaging gene expression;
  • imaging in vivo migration of cells.

The CT scanner (i.e. without PET or SPECT) can be used for the following applications in mice and rats:

  • high resolution (20-40 µm) focused CT scans;
  • medium resolution (140-200 µm) whole body CT scans;
  • bone density measurements.

MicroPET/CT Siemens


MicroSPECT/CT MILabs


More information

Otto Boerman PhD

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More information

Peter Laverman PhD

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