News

Reduction in cerebral blood flow related to decline in brain function in people with Alzheimer's disease Brain areas involved in memory and task performance show the largest decline in perfusion

Milk fat to attenuate obesity-related neurological co-morbidities

The use of lipids to attenuate co-morbidities of obesity may sound paradoxical. However, it has shown to be particularly relevant in the fight against a less familiar co-morbidity of obesity, as it can induce alterations in white matter tracks, neuroinflammation and increases the risk of dementia.

Early stage biomarker for Alzheimer's disease

Researchers from the translational metabolic lab and department of neurology, in collaboration with researchers from University of Barcelona, set out to research a new biomarker in cerebrospinal fluid called “neuroleukin” for Alzheimer's disease.

Palliative care for people with Parkinson’s Disease and their family Caregivers Current state of affairs

Advanced stage Parkinson’s disease can cause a variety of symptoms, for which palliative care can be beneficial, though research from the point of view of patients in later stages is still rare. Radboudumc researchers therefore placed their patients perspectives at the center of their recent study.

Radboudumc to lead research team into tackling future pandemics NWO funds complexity research on pandemics

The Radboudumc is going to lead a study on how to deal with future pandemics, together with Radboud University and the University of Amsterdam. Rick Quax from the Informatics Institute/IAS is involved in this project.

Treatment of brain diseases at risk if neuroscientists can no longer conduct their research

In order to treat brain diseases such as depression, Alzheimer's or ADHD, more research into the brain is needed.

On the prevalence of cerebral amyloid angiopathy a systematic review and meta-analysis

Published in ‘Alzheimers and Dementia’, researchers at Radboudumc performed a systematic review and meta-analysis on the prevalence of Cerebral Amyloid Angiopathy. They scrutinized and analyzed 170 publications, comprising publications using either a neuroimaging or a neuropathological approach.

Miniaturized microfluidic platform for automated epigenetic profiling

Together with Fluidigm, a US-based company focusing on microfluidics, the team of Hendrik Marks publishes in Genome Research the development of a powerful plug and play ChIP-seq platform for minute amount of cells, such as embryonic specimens or small biopsies.

Not treating high blood pressure in the elderly a dangerous misconception

Not treating high blood pressure in the elderly and people with dementia can lead to more heart and brain infarctions. That is the conclusion of clinical geriatrician Jurgen Claassen. He co-wrote a review article on the mechanism of brain blood flow that challenges these incorrect assumptions.

Towards the real-time monitoring of patient resilience

Research in the Department of Geriatrics has explored how quantifying a patient’s physical resilience – the ability to resist functional decline and recover physical health following a stressor – can support clinical intuition and decision-making. Results are published in Experimental Gerontology.

COVID-19 regulations for nursing homes have varying effects

On May 11th 2020, the Dutch Government allowed 26 nursing homes to welcome one visitor per resident, after two months of lockdown. An in-depth Radboudumc study monitored the feasibility of the regulations and the impact on the well-being of residents, their visitors, and healthcare staff.

Criticism against Dutch government for their anti-corona measurements

Radboudumc researcher criticized Dutch government for their measurements against corona virus, and how it took care with both old and young generations.

DCMN big data mini-symposium held on 31 January

On 31 January, DCMN researchers and collaborators gathered to talk about big data, as a means to work towards Open Science.

9 million euros made available for lifestyle research

Neuroscientist Esther Aarts has been awarded a Crossover grant from NWO for her MOCIA project. This grant will boost progress in lifestyle research for the elderly. MOCIA focuses on achieving a healthier brain during aging, and involves a public-private partnership.

Simple tool provides insight into the average life expectancy for patients with dementia

A simple tool can quickly provide patients, with a dementia diagnosis, with more clarity about their average life expectancy. This tool is developed by Radboudumc in collaboration with the Karolinska Institute in Sweden.

Healthy weight limits risk of dementia even in old age

Even late in life it makes sense to maintain a healthy weight, and thus to limit the risk of cognitive decline.

A robot for health data acquisition among older adults

In BMJ Quality & Safety Roel Boumans and colleagues from the department of Geriatrics showed that social robots may effectively and acceptably assist healthcare professionals by interviewing older adults on their perceived health status.

Exergaming as an effective method to engage people with dementia in physical exercise

In Alzheimers Research & Therapy Esther Karssemeijer and Roy Kessels from the departments of Geriatrics and Medical Psychology showed that a 12-week exergame and aerobic training improve psychomotor speed in people with dementia.

Report of the 12th New Frontiers symposium Big data, better healthcare? - 1 November 2018

Examples from the application of deep learning to image reading in pathology and radiology and the application of network medicine to monitor infectious disease outbreaks or collective mood states using twitter data showed the huge potential of big data approaches for building better healthcare.

Report of the 12th New Frontiers symposium Better care, network care? - 2 November 2018

No easy answers at this symposium last Friday, only challenges that can be overcome if we succeed in 5 things. First and most radically, put patients in the center of healthcare. Second, start with assessing what the local population needs and not what local professionals have to offer.

New technology helps physicians to look at the patient as a whole

Research from Wageningen University & Research and Radboudumc have found a way to assess the resilience of animals and humans based on data from wearable electronics.

Awardees DCMN Junior Researcher round 2019

DCMN launched a call call for Radboudumc junior researcher (PhD) positions. This year 6 positions have awarded.

Maud Graff appointed as professor of Occupational Therapy

Maud Graff has been appointed as professor (by special appointment) of Occupational Therapy at RadboudUMC and Radboud University. The chair – the first in the Netherlands - is financed by the Dutch Occupational Therapy Association ‘Ergotherapie Nederland’.

Brain specific mutations may only explain sporadic Alzheimer's disease in very few cases

Alexander Hoischen, theme Infectious diseases and global health, and colleagues studied brain- and blood-DNA of sporadic early-onset Alzheimer’s disease (AD) patients, for somatic mutations in the known AD genes.

Save the date for Radboud New Frontiers 2018: Betere zorg, netwerkzorg?

After standard care, standardized care, and personalized care, network care will be care 4.0. But how exactly do you do that? Should we create new structures for it or is it just a matter of trust and ability to step back?

Save the date for Radboud New Frontiers 2018: Big data, better healthcare?

How is big data influencing healthcare and healthcare research? How will it help us and what are the limitations? The first day of the 12th edition of the Radboud New Frontiers symposium, on 1 November 2018, will give you all the answers (and raises new questions).

Register now for RIMLS PhD Retreat

Tomorrow 2 February is the last chance for the early bird registration for the RIMLS PhD retreat 2018.

2.5 million euro for research on dementia Deltaplan Dementia

The national funding programme Memorabel II awarded funding for six research projects and three partner projects. This will bolster research on dementia at Radboudumc and the Donders Institute.

Disturbed deep sleep creates deposits of Alzheimer proteins detectable effects on the brain after a single night

Disturbed sleep causes an increase of amyloid beta in the brain. A single night of poor sleep is sufficient to cause a detectable effect on the brain already.