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Three quarters of women in the Netherlands use some form of medication during pregnancy, but little is known about the appropriate dosages. Research by the Radboudumc, MUMC+ and Lareb Mothers of Tomorrow should change this.
The online care concept Luchtbrug, an initiative of Radboudumc, is an effective way to monitor and supervise children with asthma. Following the use of Luchtbrug, children need to visit the hospital less often.
On 18 February the RIHS 'Koek & Zopie' event took place. In front of an audience of more than 125 colleagues, RIHS awardees accepted their awards for the best PhD thesis, the research product with the highest impact on society, the best peer-reviewed publication and the Supervisor of the year 2019.
Pharmaceutical company Khondrion, a spin-off from Radboudumc, has taken another important step in the development of its drug sonlicromanol. The first patients have used the drug as part of a phase 2b study, which focuses on determining the optimum dose and efficacy.
Daan Panneman & Richard Rodenburg have been awarded a Stofwisselkracht grant for their proposal “CRISPR/Cas9 knock-in complementation in fibroblasts of mitochondrial disease patients”. Together with Omar Tutakhel & Jan Smeitink they will investigate the possibility of using CRISPR/Cas9 knock-in.
The group of Hans Spelbrink, theme Mitochondrial diseases, and colleagues, has identified and characterized mutations in the mtDNA maintenance gene SSBP1 in families with optic atrophy and foveopathy. This paper is now online in The Journal of Clinical Investigation.
The European Complement Network (ECN) is a Pan-European non-profit scientific organization managed by researchers and clinicians investigating the complement system (part of the innate immunity) and/or diseases related to it.
This fall, all Dutch hospitals with a pediatric ward will have the possibility to implement a single signaling system that provides early warnings to caretakers as soon as the vital functions of admitted children are in danger.
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Hedi Claahsen.
Hans Spelbrink, theme Mitochondrial diseases, published in Nucleic Acids Research, that two factors in mitochondrial DNA replication, namely the mtDNA helicase Twinkle and the mtDNA single-stranded DNA-binding protein mtSSB, play an important role in mitochondrial RNA metabolism.
For patients with a rare or complex urogenital disease or condition, eUROGEN is the European Reference Network.
This price is awarded each year by Kika (kinderen kankervrij) for excellent research in the area of pediatric oncology.
Alfredo Cabrera-Orefice, Ulrich Brandt and colleagues, theme Mitochondrial Diseases, concluded in Nature Communications that the movement of a critical loop of subunit ND3 located at the ubiquinone-binding pocket of respiratory complex I is required to drive proton pumping.
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Marloes Michels.
Researchers of the Radboudumc and colleagues have successfully developed enzyme-loaded polymersomal nanoreactors capable of undergoing cellular integration in a controlled fashion and, subsequently, function as synthetic organelles.
Rosa Geurtzen was awarded as appreciation for her role in a project that contributes to making effective choices in healthcare. She received the scholarship for the PreCo study, in which prenatal counseling in extreme preterm birth is optimized.
This price is handed out each year bij Kika (kinderen kankervrij) for excellent research in the area of pediatric oncology.
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