News

New mitochondrial DNA maintenance disease uncovered

The group of Hans Spelbrink, theme Mitochondrial diseases, and colleagues, has identified and characterized mutations in the mtDNA maintenance gene SSBP1 in families with optic atrophy and foveopathy. This paper is now online in The Journal of Clinical Investigation.

Elena Volokhina elected as president of the ECN board

The European Complement Network (ECN) is a Pan-European non-profit scientific organization managed by researchers and clinicians investigating the complement system (part of the innate immunity) and/or diseases related to it.

Implementation of single national warning system will make pediatric wards even safer

This fall, all Dutch hospitals with a pediatric ward will have the possibility to implement a single signaling system that provides early warnings to caretakers as soon as the vital functions of admitted children are in danger.

A personal touch of Hedi Claahsen

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Hedi Claahsen.

Mitochondrial DNA replication factors in mtRNA metabolism

Hans Spelbrink, theme Mitochondrial diseases, published in Nucleic Acids Research, that two factors in mitochondrial DNA replication, namely the mtDNA helicase Twinkle and the mtDNA single-stranded DNA-binding protein mtSSB, play an important role in mitochondrial RNA metabolism.

Wout Feitz new coordinator EU ERN eUROGEN

For patients with a rare or complex urogenital disease or condition, eUROGEN is the European Reference Network.

Kika young investigator award for Kirsten Vrenken

This price is awarded each year by Kika (kinderen kankervrij) for excellent research in the area of pediatric oncology.

Tweaking the gearbox of mitochondrial complex I

Alfredo Cabrera-Orefice, Ulrich Brandt and colleagues, theme Mitochondrial Diseases, concluded in Nature Communications that the movement of a critical loop of subunit ND3 located at the ubiquinone-binding pocket of respiratory complex I is required to drive proton pumping.

A personal touch of Marloes Michels

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Marloes Michels.

Biodegradable nanoreactors demonstrate ROS shielding in human-complex-I-deficient fibroblasts

Researchers of the Radboudumc and colleagues have successfully developed enzyme-loaded polymersomal nanoreactors capable of undergoing cellular integration in a controlled fashion and, subsequently, function as synthetic organelles.

Decision-making in extreme prematurity awarded by ZonMW

Rosa Geurtzen was awarded as appreciation for her role in a project that contributes to making effective choices in healthcare. She received the scholarship for the PreCo study, in which prenatal counseling in extreme preterm birth is optimized.

Kika young investigator award for René Marke

This price is handed out each year bij Kika (kinderen kankervrij) for excellent research in the area of pediatric oncology.

Publication in Journal of Allergy and Clinical Immunology