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Inflammatory diseases About theme

Our mission is to understand and control inflammatory disease for the benefit of each individual patient.

To realize this mission, we defined three lines of research along the spectrum of molecule-man-population:

Pathophysiology of inflammation
Personalized medicine in practice
Population-based biomarker studies

Objectives

We aim to unravel the (immune)pathogenesis of inflammatory disease processes and the efficacy and side effects of current treatments.
We will assess the role of tissue-specific factors in regulating local immunity and inflammation.
We will identify druggable genes and develop anti-inflammatory drugs.
We will identify biomarkers for personalized therapy and investigate treatment approaches using biomarkers as co-diagnostics.
We aim to capture disease severity in validated outcome measures and assess side effects of treatments in real clinical practice.
We will perform (pharmaco)genetic and epidemiological studies to identify risk factors associated with disease susceptibility, severity and treatment outcome.