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Research Themes Neuro--developmental disorders News
The following news items are related to the research Neuro­developmental disorders.
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Britt Mossink wins Dutch Neurofederation Thesis Prize 2022

28 June 2022

Britt Mossink has won the Dutch Neurofederation Thesis Prize 2022 for his thesis The cell-type specific contribution of EHMT1 to neuronal network dysfunction in Kleefstra syndrome. She received the prize and gave a lecture about her thesis, at the Dutch Neuroscience Meeting, in Tiel.

Scientists find that the impact of social media on wellbeing varies across adolescence

29 March 2022

Girls and boys might be more vulnerable to the negative effects of social media use at different times during their adolescence, say an international team of scientists in a study published today in Nature Communications.

Rogier Kievit and Geert Litjens both receive ERC Starting Grant of 1.5 million euros Board of Directors congratulates researchers on top grant

13 January 2022

Researchers Rogier Kievit and Geert Litjens were today festively welcomed by the Board of Directors, because of the ERC Starting Grants they both received. With these European top grants, they can each design an ambitious research project and put together their own research group.

KNAW Early Career Award for Martine Hoogman

2 December 2021

Martine Hoogman has been awarded a KNAW Early Career Award. The prize, a sum of 15,000 euros and a work of art, is aimed at researchers in the Netherlands who are at the start of their careers and have innovative, original research ideas.

The Effects of Intermittent Fasting on Brain and Cognitive Function

10 November 2021

Intermittent Fasting is a type of diet in which one refrains from eating for periods of time. It is known that it has positive effects on metabolic health, but what is the effect of this diet on brain and cognition? Radboudumc researchers reviewed experimental evidence on this topic.

BRAINMODEL: precision medicine for brain disorders

3 November 2021

A team of researchers is going to look for new and better ways to heal developmental disorders in the brain. Six different knowledge institutions are to collaborate with civil societies, professional associations and companies on new stem cell-based methods in a project entitled ‘BRAINMODEL’.

More frequent genetic testing required in children with language delays

8 October 2021

Genetic cause for developmental language and speech disorder in child provides relief for parents. Lot Snijders Blok describes errors in five new genes.

Study shows no relation between breastfeeding and inhibitory control in three-year-old children

15 September 2021

New study from Radboudumc researchers, investigated whether breastfeeding was related to inhibitory control, the ability to control impulsive behavior, of 3-year-old children, and whether diet played an intermediate role in this relation.

Treatment of brain diseases at risk if neuroscientists can no longer conduct their research

5 August 2021

In order to treat brain diseases such as depression, Alzheimer's or ADHD, more research into the brain is needed.

Gut microbiota alleviates effects of stress on cognition

3 June 2021

Researchers from the Radboudumc and Donders Institute have shown that the gut microbiota is involved in the protecting effects of probiotics on cognitive performance in acute stress circumstances. Their results are now published in Translational Psychiatry.

Families with a child with ADHD can benefit from mindfulness training

27 May 2021

Publication in Journal of Child Psychology and Psychiatry

Miniaturized microfluidic platform for automated epigenetic profiling

6 May 2021

Together with Fluidigm, a US-based company focusing on microfluidics, the team of Hendrik Marks publishes in Genome Research the development of a powerful plug and play ChIP-seq platform for minute amount of cells, such as embryonic specimens or small biopsies.

Higher education does not influence how the brain ages

28 April 2021

Contrary to popular belief, a new study from the Lifebrain consortium at the University of Oslo finds that higher education does not slow brain aging. Radboudumc and Donders Institute researcher Rogier Kievit is also part of this study.

Brain region controls pathological aggression but leaves context-appropriate aggresion intact

21 April 2021

In recent work published in Current Biology, researchers from Radboudumc and Donders Institute, as well as other international collaborators, showed that in mice, anterior cingulate cortex dials down excessive aggression, but leaves context-appropriate aggression intact.

Lack of evidence for genetic defects in previously implicated gene in patients with male infertility

20 April 2021

In a letter to Cell, researchers from the department of Human Genetics at Radboudumc have raised concerns about the claimed role of PIWIL1 D-box region mutations in human male infertility in an earlier publication in the same journal.

ADHD-related alterations in brain organization based on different brain profiles

14 April 2021

Structural differences between the brains of people with and without ADHD are extensively reported. In accordance with earlier (ENIGMA) studies, and using a large cohort, a newly published study builds upon these by showing differences in brain organization that is based on different brain profiles.

Seven million cases of Parkinson's disease The fastest growing brain disease in the world

13 April 2021

Over seven million people worldwide have Parkinson's disease, and it is the fastest growing brain disease in the world. Different forms of personalized treatment plans are needed. This is what Radboudumc neurologist Bas Bloem writes in a review article published in The Lancet.

SATB1 - Three classes of mutations and their unique rare diseases

18 February 2021

Recent advances in DNA sequencing technologies have made it possible to uncover the causes of multiple rare diseases. A new collaborative study describes how three classes of mutation within the same gene result in different neurodevelopmental disorders.

Cell-type specific changes induced by culturing on microfluidic chips.

10 February 2021

A collaborative TURBO (Twente University RadBoudumc Opportunities) project, recently published in Scientific Reports, developed an organ-on-a-chip device which can be used for modelling the neurovascular unit (NVU).

Four new professors explain the need for cooperation in developmental neuroscience

27 January 2021

In the past, developmental neuroscience was not a field in which people from different disciplines cooperated very much. However, in recent years, the approach has been gradually changing. Four newly appointed professors at Radboudumc/ the Donders Institute understand the importance of teaming up.

Nael Nadif Kasri receives 250k Euro from European Joint Programme on Rare Diseases (EJP-RD)

7 January 2021

Nael Nadif Kasri, Department of Cognitive Neurosciences, Human Genetics theme Neurodevelopmental disorders, received 250,000 Euro as a member of the SCN1A-UP! consortium.

ERC Consolidator Grant for André Marquand

10 December 2020

André Marquand, theme Neurodevelopmental disorders, has been awarded an ERC Consolidator Grant. With this grant of two million euros, he can develop a new research project.

New genetic cause for vision impairment and blindness discovered

8 October 2020

After thirty years of research, the genetic defect that causes the eye disease retinitis pigmentosa type 17 (RP17) has finally been discovered.

Tjitske Kleefstra appointed endowed professor of Clinical genetics and psychopathology of rare syndromes

17 September 2020

Tjitske Kleefstra has been appointed endowed professor of Clinical genetics and psychopathology of rare syndromes at the department of Neurodevelopmental disorders, with effect from 1 September.

Annette Schenck appointed professor of Translational Genomics of Neurodevelopmental Disorders

17 September 2020

Annette Schenck has been appointed professor of Translational Genomics of Neurodevelopmental Disorders. with effect from 1 August. The chair will bring together fundamental and translational research in the field of brain developmental disorders.

Nanda Rommelse appointed endowed professor of Neurodevelopmental disorders

8 September 2020

Nanda Rommelse has been appointed professor of Neurodevelopmental disorders with effect from 1 September. The chair will function as a bridge between the Psychiatry Department of the Radboudumc with Karakter Child and Adolescent Psychiatry.

Largest comparative study provides insights for childhood-onset mental disorders

23 June 2020

The worlds’ largest comparative study with brain scans of patients with ADHD, ASD and OCD showed subtle, but interesting, differences in subcortical and cortical brain structures.

Gene SETD1A bridges a rare genetic syndrome to schizophrenia

6 May 2020

Tjitske Kleefstra, Diante Stremmelaar and Joost Kummeling, in collaboration with colleagues in an international cohort study, have shown that mutations in the SETD1A gene cause a defined rare syndrome.

Gut microbiota from AD(H)D patients affects mice brain

8 April 2020

In a recent study, published in the journal Microbiota, Radboudumc researchers showed that gut microbiota from AD(H)D patients can cause brain alterations in mice.

Worldwide study cracks brain’s genetic code

2 April 2020

A massive genetic study of the human cerebral cortex, the deeply wrinkled sheet of neurons covering the brain, identifies hundreds of genes that give rise to its physical characteristics, which are as unique to each person as a fingerprint.

Jan Buitelaar coordinates CANDY research project

11 March 2020

The European funded research project CANDY investigates the biological links between these neurodevelopmental disorders and co-occurring somatic illnesses and how treatment and monitoring of affected patients can be improved.

Radboudumc and LUMC launch center for RNA therapy for ultrarare diseases

4 March 2020

The aim of this new virtual centre is to develop customised RNA therapies for patients with rare genetic conditions. Several DCMN researchers and medical specialists are involved in DCRT.

Researchers at Radboud university medical center find gene with two faces

4 March 2020

Mutations in the SPOP gene cause two different syndromes with associated intellectual disability

Three Vici grants for Radboudumc researchers

20 February 2020

Christian Beckmann, Sander Leeuwenburgh and Annette Schenck each receive a 1.5 million euro Vici research grant from NWO.

DCMN big data mini-symposium held on 31 January

5 February 2020

On 31 January, DCMN researchers and collaborators gathered to talk about big data, as a means to work towards Open Science.

6 million euros to uncover link between metabolic and brain disorders

21 January 2020

An important European-funded initiative, coordinated by Radboudumc researchers Barbara Franke, Jan Buitelaar, and Janita Bralten, has been launched to explore how common molecular mechanisms may link metabolic disorders with brain disorders.

Rubicon Grant for Marieke Klein

14 January 2020

DCMN researcher Marieke Klein, theme Neurodevelopmental disorders, received a Rubicon Grant from the Dutch Organisation for Scientific Research (NWO). The Rubicon program gives young, highly promising researchers the opportunity to gain international research experience.

Two DCMN researchers in top 1 percent by citations

28 November 2019

Jan Buitelaar and Christian Beckmann made it to this year’s list of highly cited researchers. Researchers in this list are selected for their exceptional research performance and are regarded to have had a major impact on fellow scientists.

1.5 million for research into young people with mild intellectual disabilities

13 November 2019

Researchers from the Radboud University and Radboudumc will partner with social organisations to map how often young people with mild intellectual disabilities have psychological problems and how they can be treated. The project was recently awarded a subsidy of 1.5 million euro by ZonMw.

Self-management rehabilitation program improves participation in patients with neuromuscular disease

4 November 2019

Yvonne Veenhuizen, Alexander Geurts theme Neurorehabilitation, Baziel van Engelen, theme Disorders of movement, and colleagues, showed that Energetic improves participation in patients with neuromuscular disease. They have published their results in Neurology.

Towards molecular therapies for Myotonic Dystrophy

1 October 2019

ReCognitION, a new 1.3 M€ European project under the leadership of Peter-Bram ‘t Hoen, Baziel van Engelen and Jeffrey Glennon, was kicked-off in Gent.

Hans van Bokhoven newly elected in Academia Europaea

22 August 2019

The Academia Europaea is a functioning European Academy of Humanities, Letters and Sciences, composed of individual members.

Front cover Human Mutation

21 August 2019

The MetaDome web server build to interpret genetic variants based on genetic tolerance and homologous protein domains is featured on the Cover of Human Mutation. MetaDome was developed by Laurens van de Wiel, Coos Baakman, Daan Gilissen, Joris Veltman, Gert Vriend and Christian Gilissen,

How a gene called G9a regulates the energy supply for stress

18 March 2019

In order to survive, all organisms must be able to detect (threatening) changes in their environment and respond to them adequately and quickly. However, such stress responses (e.g., escape from a predator or immune response to an infection) are very energy-consuming.

Genetic overlap between ADHD and brain volumes

6 March 2019

In the American Journal of Psychiatry Marieke Klein and Barbara Franke showed that significant genetic overlap exists between brain volume measures and ADHD, both on the global and the single variant level.

Who is the average patient with ADHD? Does he or she exist?

4 March 2019

In Psychological Medicine Thomas Wolfers and André Marquand showed that the average patient with ADHD does not exist biologically.

Adjunct Professorship awarded to Barbara Franke at the Goethe University in Frankfurt am Main

21 January 2019

Barbara Franke is awarded an honorary Adjunct Professorship at the Goethe University in Frankfurt am Main in Germany.

3 DCMN researchers among most cited scientists

10 December 2018

Christian Beckmann, Jan Buitelaar and Barbara Franke made it to this year’s list of highly cited researchers. Scientists in this list are selected for their exceptional research performance and are regarded to have had a major impact on fellow scientists.

Researchers have found the first risk genes for ADHD New insight into the biology behind ADHD.

28 November 2018

A major international collaboration headed by researchers from the Danish iPSYCH project, the Broad Institute of Harvard and MIT, and the Psychiatric Genomics Consortium has - for the first time - identified genetic variants which increase the risk of ADHD.

TURBO grants for four medical-technical research projects

8 November 2018

Four TURBO grants were awarded to new technical-medical research proposals. The grants are part of the TURBO program, a collaboration between Radboudumc and the University of Twente.