Effectiveness and predictors of response to somatostatin analogues in patients with gastrointestinal angiodysplasias15 September 2021
Lia Goltstein and colleagues published a study about effectiveness and predictors of response to somatostatin analogues in patients with gastrointestinal angiodysplasias: a systematic review and individual patient data meta-analysis.
Christa Sperna Weiland, Erwin van Geenen and Joost Drenth discuss the best strategy to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis28 July 2021
Christa Sperna Weiland, Erwin van Geenen and Joost Drenth, published in Lancet Gastroenterology & Hepatology a systematic review and network meta-analysis to determine the most efficacious prophylaxis strategy to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis.
Aggressive periprocedural hydration + rectal NSAID: no reduction in incidence of post-ERCP pancreatitis1 June 2021
Aggressive fluid hydration plus non-steroidal anti-inflammatory drugs versus non-steroidal anti-inflammatory drugs alone for post-endoscopic retrograde cholangiopancreatography pancreatitis (FLUYT): a multicentre, open-label, randomised, controlled trial.
Miniaturized microfluidic platform for automated epigenetic profiling6 May 2021
Together with Fluidigm, a US-based company focusing on microfluidics, the team of Hendrik Marks publishes in Genome Research the development of a powerful plug and play ChIP-seq platform for minute amount of cells, such as embryonic specimens or small biopsies.
Dutch Children's Formulary now also in use abroad Drug database for pediatric dosing available online for German, Austrian and Norwegian physicians30 April 2021
The Kinderformularium, developed in the Netherlands, now also provides pediatricians and pharmacists abroad with a database of drug dosage recommendations specifically aimed at treating children.
E-learning avoids gastroscopy in patients with stomach complaints28 April 2021
Many patients with stomach complaints who are referred for a gastroscopy actually do not need that unpleasant examination. Thanks to an e-learning module, they become more aware of their complaints and many of them refrain from such an examination.
Cross communication between nephron segments by extracellular vesicles13 April 2021
In the FASEB Journal, Joost Hoenderop and other researchers, theme Renal disorders, demonstrated that purinergic signaling and αENaC mRNA expression is controlled by extracellular vesicles flowing along the nephron segments.
Discovery of new protein with an important role in atherosclerosis11 March 2021
Atherosclerosis is the underlying condition that causes heart attacks and strokes. Researchers at Radboudumc in the Netherlands have discovered a protein that appears to play an important role in atherosclerosis. The protein is called Prosaposin.
ZonMw grants to study optimal use of COVID-19 vaccines in patients with impaired immune systems3 February 2021
How do people with reduced immunity, especially kidney patients, react to a COVID-19 vaccination? And how can patients with peripheral arterial disease be helped by DNA testing? Our researchers received grants from ZonMw to make these studies possible.
RIMLS online award ceremony proudly presenting the winners13 January 2021
In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony.
Transfer of new anti-hepatitis C drugs across the human placenta9 September 2020
In a recent publication in American Journal of Obstetrics and Gynecology, researchers from the Departments of Pharmacology and Toxicology, Pharmacy, Obstetrics and Gynecology, Gastroenterology and Hepatology, investigated the placental passage of two such drugs for the first time.
Safer and more effective use of medicines in children How 'virtual children' will make a difference31 August 2020
The efficacy and safety of about half of all drugs prescribed to children has not been adequately researched. Because growth and development change the way a child's body deals with drugs, it runs an increased risk of receiving ineffective or unsafe drugs.
Molecular scissors play a role in kidney and lung leakage in COVID-19 patients18 June 2020
‘Molecular scissors', play a role in leakage of fluid from blood vessels to lungs and kidneys in COVID-19 patients. The scissors cut the protective sugar layer in the blood vessels. The more serious the disease, the more active the scissors, wrote Johan van der Vlag and colleagues in MedRxiv.
New insight into the effect of hydroxychloroquine undermines its use in corona11 June 2020
Researchers at Radboud university medical center have discovered an as yet unknown effect of hydroxychloroquine. Raphael Duivenvoorden was interviewed in the program Op1 at NPO1 to elaborate on the findings. It seems unlikely that chloroquine has beneficial effect in corona infections.
Johan van der Vlag appointed as professor of Immunology of Kidney Diseases and Transplantation23 April 2020
Johan van der Vlag is an expert in unravelling the molecular and immunological mechanisms underlying kidney disease and transplantation. His research stems from clinical questions and focuses on the development of new diagnostic/prognostic and therapeutic strategies.
Gene controls the formation of photosensitive disks in retinal cells21 April 2020
Researchers have unraveled a molecular mechanism that regulates the build-up of the photosensitive segments in the cones and rods in the retina. A protein PCARE, controls this process. These new insights, published in PNAS USA, could make a significant contribution to new therapies for eye diseases.
NWO Open Competition ENW - KLEIN grant for Jenny van der Wijst9 March 2020
KLEIN grants offer researchers the possibility to realize curiosity-driven, fundamental research and elaborate creative and risky ideas. For this project, Jenny is seeking an enthusiastic postdoc to join her team working on ion channels.
Dutch Kidney Foundation PhD grant for Johan van der Vlag and Tom Nijenhuis14 February 2020
Johan van der Vlag and Tom Nijenhuis, theme Renal disorders, received this grant for their joint research project “Targeting a novel paracrine signaling pathway between glomerular endothelium and podocytes to treat glomerular injury”.
RIMLS PhD retreat registration is open23 January 2020
Yearly, RIMLS PhD candidates gather for the two-day PhD Retreat. Apart from the science, this event is highly valued for the opportunity to meet and get to know fellow PhD candidates during the social activities. Early bird registration and abstract submission deadline: 4 March 2020.
NWO Open Competition Domain Science - XS grant for Ronald van Rij and Jenny van der Wijst21 January 2020
NWO Domain Science has awarded Ronald van Rij, theme Infectious diseases and global health and Jennny van der Wijst, theme Renal disorders an XS grant. The XS category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea.