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Research Themes Renal disorders News
The following news items are related to the research Renal disorders.
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Miniaturized microfluidic platform for automated epigenetic profiling

6 May 2021

Together with Fluidigm, a US-based company focusing on microfluidics, the team of Hendrik Marks publishes in Genome Research the development of a powerful plug and play ChIP-seq platform for minute amount of cells, such as embryonic specimens or small biopsies.

Dutch Children's Formulary now also in use abroad Drug database for pediatric dosing available online for German, Austrian and Norwegian physicians

30 April 2021

The Kinderformularium, developed in the Netherlands, now also provides pediatricians and pharmacists abroad with a database of drug dosage recommendations specifically aimed at treating children.

Embryonic development and magnesium homeostasis is regulated by Cyclin M2

29 April 2021

Gijs Franken and colleagues, theme Renal disorders, published in Scientific Reports that Cyclin M2 (CNNM2) is vital for embryonic development and magnesium homeostasis.

E-learning avoids gastroscopy in patients with stomach complaints

28 April 2021

Many patients with stomach complaints who are referred for a gastroscopy actually do not need that unpleasant examination. Thanks to an e-learning module, they become more aware of their complaints and many of them refrain from such an examination.

Cross communication between nephron segments by extracellular vesicles

13 April 2021

In the FASEB Journal, Joost Hoenderop and other researchers, theme Renal disorders, demonstrated that purinergic signaling and αENaC mRNA expression is controlled by extracellular vesicles flowing along the nephron segments.

Bifunctional protein PCBD2 operates as a co‐factor for hepatocyte nuclear factor 1β and modulates gene transcription.

30 March 2021

Lotte Tholen, theme Renal disorders, and colleagues published in the FASEB Journal that PCBD1 and PCBD2 exert different effects on HNF1β‐mediated transcription.

Bifunctional protein PCBD2 operates as a co‐factor for hepatocyte nuclear factor 1β and modulates gene transcription.

30 March 2021

Lotte Tholen, theme Renal disorders, and colleagues published in the FASEB Journal that PCBD1 and PCBD2 exert different effects on HNF1β‐mediated transcription.

Michiel Schreuder appointed Professor of Pediatric Nephrology

18 March 2021

Michiel Schreuder appointed full professor of Pediatric Nephrology as of 16 January 2021.

Iron Expertise Center will be transferred from Radboudumc to Sanquin

17 March 2021

The strong connection with Radboudumc will be maintained by current head of the expertise center Dorine Swinkels, who will be employed by both Sanquin and Radboudumc.

Discovery of new protein with an important role in atherosclerosis

11 March 2021

Atherosclerosis is the underlying condition that causes heart attacks and strokes. Researchers at Radboudumc in the Netherlands have discovered a protein that appears to play an important role in atherosclerosis. The protein is called Prosaposin.

Academic Alliance Fund (AAF) grant for Cansu Yanginlar and Johan van der Vlag

10 March 2021

They received 100 kEuro for their project “NETworking: Deciphering the pathologic properties of the neutrophil in COVID-19, ANCA-associated vasculitis (AAV), and systemic lupus erythematosus (SLE).

Dutch Kidney Foundation Innovation Grant for Tom Nijenhuis and Jeroen de Baaij

17 February 2021

This innovation grant was awarded for their project “A sweet deal: repurposing SGLT2i for renal hypomagnesemia”.

Dysfunction of the ciliary ARMC9/TOGARAM1 protein module causes Joubert syndrome

16 February 2021

Brooke L. Latour, theme renal disorders, published an interesting article on the cause of the Joubert syndrome in the Journal of Clinical Investigation.

Marie Curie Fellowship for Juan Pablo Rigalli

11 February 2021

RIMLS postdoc Juan Pablo Rigalli, theme Renal disorders, is awarded with a Marie Curie Fellowship from the European Commission to study the application of extracellular vesicles in precision pharmacotherapy.

ZonMw grants to study optimal use of COVID-19 vaccines in patients with impaired immune systems

3 February 2021

How do people with reduced immunity, especially kidney patients, react to a COVID-19 vaccination? And how can patients with peripheral arterial disease be helped by DNA testing? Our researchers received grants from ZonMw to make these studies possible.

RIMLS online award ceremony proudly presenting the winners

13 January 2021

In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony. 

Dutch Digestive Foundation grant for Joost Drenth

13 January 2021

Joost Drenth, theme Renal disorders, received a Dutch Digestive Foundation grant in cooperation with his colleagues from Amsterdam UMC and Leiden UMC.

A better understanding of iron deficiency with new insights

16 December 2020

Dorine Swinkels, together with her colleagues, provides scientific evidence-based guidance on how iron deficiency should be diagnosed and treated to ensure positive health effects over time.

Vote for the Supervisor of the year

10 December 2020

Now you have the chance to vote for your preferred candidate. Have fun, and go for it, support and promote your ideal supervisor. Please submit your vote at the latest 4 January 2021.

COVID-19 and the kidney overview of papers

26 November 2020

Within the research theme Renal Disorders several studies were initiated to contribute to the knowledge on COVID-19. Check out our overview of the papers that originated from these studies.

Hydroxychloroquine against malaria appears to block 'trained immunity'

25 November 2020

Raphaël Duivenvoorden and colleagues have discovered an as yet unknown effect of hydroxychloroquine, which are published in Cell Reports Medicine.

Multiple prizes for nephrological researchers

24 November 2020

A rain of prizes was awarded to colleagues from the research theme Renal Disorders during the combined Dutch Nephrology Days and Scientific Fall symposium of the Dutch Federation for Nephrology (NFN).

The best thesis prize 2019 within Nephrology awarded to Kioa Wijnsma

28 October 2020

Kioa Wijnsma, theme Renal disorders, won the best thesis award 2019 within Nephrology

Transfer of new anti-hepatitis C drugs across the human placenta

9 September 2020

In a recent publication in American Journal of Obstetrics and Gynecology, researchers from the Departments of Pharmacology and Toxicology, Pharmacy, Obstetrics and Gynecology, Gastroenterology and Hepatology, investigated the placental passage of two such drugs for the first time.

Safer and more effective use of medicines in children How 'virtual children' will make a difference

31 August 2020

The efficacy and safety of about half of all drugs prescribed to children has not been adequately researched. Because growth and development change the way a child's body deals with drugs, it runs an increased risk of receiving ineffective or unsafe drugs.

Molecular scissors play a role in kidney and lung leakage in COVID-19 patients

18 June 2020

‘Molecular scissors', play a role in leakage of fluid from blood vessels to lungs and kidneys in COVID-19 patients. The scissors cut the protective sugar layer in the blood vessels. The more serious the disease, the more active the scissors, wrote Johan van der Vlag and colleagues in MedRxiv.

New insight into the effect of hydroxychloroquine undermines its use in corona

11 June 2020

Researchers at Radboud university medical center have discovered an as yet unknown effect of hydroxychloroquine. Raphael Duivenvoorden was interviewed in the program Op1 at NPO1 to elaborate on the findings. It seems unlikely that chloroquine has beneficial effect in corona infections.

Johan van der Vlag appointed as professor of Immunology of Kidney Diseases and Transplantation

23 April 2020

Johan van der Vlag is an expert in unravelling the molecular and immunological mechanisms underlying kidney disease and transplantation. His research stems from clinical questions and focuses on the development of new diagnostic/prognostic and therapeutic strategies.

Gene controls the formation of photosensitive disks in retinal cells

21 April 2020

Researchers have unraveled a molecular mechanism that regulates the build-up of the photosensitive segments in the cones and rods in the retina. A protein PCARE, controls this process. These new insights, published in PNAS USA, could make a significant contribution to new therapies for eye diseases.

Martinus van Marum prize for Tom Schirris

3 April 2020

This award of € 12,500 is intended as an incentive prize for researchers who have obtained their PhD degree in 2015 or later. The jury, consisting of members of the Society, came to this decision unanimously.

NWO Open Competition ENW - KLEIN grant for Jenny van der Wijst

9 March 2020

KLEIN grants offer researchers the possibility to realize curiosity-driven, fundamental research and elaborate creative and risky ideas. For this project, Jenny is seeking an enthusiastic postdoc to join her team working on ion channels.

Dutch Kidney Foundation PhD grant for Johan van der Vlag and Tom Nijenhuis

14 February 2020

Johan van der Vlag and Tom Nijenhuis, theme Renal disorders, received this grant for their joint research project “Targeting a novel paracrine signaling pathway between glomerular endothelium and podocytes to treat glomerular injury”.

Marie Curie Global Fellowship for Maria Ibars Serra

7 February 2020

RIMLS postdoc Maria Ibars Serra, theme Renal disorders, is awarded with a Marie-Curie Global Fellowship. The next three years she will focus on unraveling the role of a mysterious gene involved in magnesium balance in the body.

RIMLS PhD retreat registration is open

23 January 2020

Yearly, RIMLS PhD candidates gather for the two-day PhD Retreat. Apart from the science, this event is highly valued for the opportunity to meet and get to know fellow PhD candidates during the social activities. Early bird registration and abstract submission deadline: 4 March 2020.

NWO Open Competition Domain Science - XS grant for Ronald van Rij and Jenny van der Wijst

21 January 2020

NWO Domain Science has awarded Ronald van Rij, theme Infectious diseases and global health and Jennny van der Wijst, theme Renal disorders an XS grant. The XS category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea.

Rubicon Grant for Sami Mohammed

14 January 2020

Former RIMLS researcher Sami Mohammed, theme Renal disorders, received a Rubicon Grant from the Dutch Organisation for Scientific Research (NWO). The Rubicon program gives young, highly promising researchers the opportunity to gain international research experience.

Kolff grants Dutch Kidney Foundation for Raphaël Duivenvoorden and Jitske Jansen

17 December 2019

The Dutch Kidney Foundation supports talented postdocs and physician researchers through providing personal grants that support different phases of a research career. This year Raphaël Duivenvoorden and Jitske Jansen, theme Renal disorders, received a Kolff grant.

Vote for the Supervisor of the year

12 December 2019

Deadline for voting is closed. The three nominated finalists are: Joost Drenth, Marien de Jonge and Iris Nagtegaal.

E-rare grant for Joost Hoenderop

9 December 2019

Joost Hoenderop, theme Renal disorders, received an European Joint Programme Rare Diseases grant for his project, entitled 'Improving diagnostics and grasping the disease mechanisms of rare hypomagnesemia in patients with CNNM2 mutations'. 

Response to treatment of Autoimmune Hepatitis

6 December 2019

Simon Pape and Joost Drenth published in Clinial Gastroenterology and Hepatology that a rapid response to treatment associates with normalization of transaminase levels in patients with Autoimmune Hepatitis.

A personal touch of Mark van Goor

28 November 2019

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Mark van Goor.

RIMLS awards call for nominations

26 November 2019

RIMLS awards several prizes to stimulate and honor our (young) researchers. Please find here an overview of the upcoming awards. Deadline 12 December 2019.

A personal touch of Marlies Cornelissen

31 October 2019

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Marlies Cornelissen.

X² Ambition Award for Sandra Heskamp

28 October 2019

This award is intended for 'coming women’: young, ambitious women at a stage of their careers where they make important career choices. This prize is especially for women who show exemplary behaviour within the organization where they work, but also outside their organization.

Awardees RIHS Junior Researcher round 2020

23 October 2019

Recently, RIHS held an internal call for Radboudumc junior researcher (PhD) positions. This year 6 positions have been awarded.

KWF Roadshow 11 November 2019

10 October 2019

In which way(s) can KWF provide optimal support to oncological research and care? How can we maximize impact on our investments? These questions are pivotal in Ambition 2030: the vision that KWF developed in close cooperation with stakeholders in the oncological field.

Dorine Swinkels collaborates with winners of the Nobel Prize in Physiology or Medicine

9 October 2019

The Nobel Prize in Physiology or Medicine 2019 was awarded jointly to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza for their discoveries of how cells sense and adapt to oxygen availability.

Scaling up nanotherapy

7 October 2019

Scaling up and translating nanotherapy from pre-clinical work in small animal models to a clinical application is not trivial. Raphael Duivenvoorden, theme Renal disorders, and colleagues, published their results on translating a new nanoimmunotherapy in the journal Science Translational Medicine.

RIMLS 25 years jubilee festival The Future is Yesterday

3 October 2019

Together with more than 250 colleagues and alumni we celebrated 25 years of research into the molecular mechanisms of disease. During this exciting and informal event, we not only took a trip down memory lane, but also looked ahead to the next 25 years and beyond…...

A personal touch of Juan Pablo Rigalli

26 September 2019

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Juan Pablo Rigalli.

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