A "QR code" to read metabolism inside prostate cells: labeled extra-cellular citrate12 April 2022
In a recent publication in the Proceedings of the National Academy of Sciences USA, Frits van Heijster and his colleagues describe investigations to uncover which carbon sources and metabolic pathways are used by epithelial cells of the prostate to sustain high luminal citrate levels.
Body composition is more important than BMI for renal cancer survival rates11 January 2022
Body composition is important for survival rates in renal cell cancer. Research from the Radboudumc shows that low muscle quality and low organ fat are associated with poor survival. This involves different stages of renal cancer, ranging from stage I-III to stage IV.
Millions of euros for study of laser treatment for glioblastoma2 April 2021
A research group from Radboudumc and UMC Utrecht is to investigate laser treatment of a rare brain tumor, glioblastoma. 3.9 million euros has been made available for the research by Zorginstituut Nederland and ZonMw, under the auspices of the Subsidy Scheme for Promising Care.
RIMLS online award ceremony proudly presenting the winners13 January 2021
In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony.
Plugging the gap ZonMw/Health Holland grant3 March 2020
RIMLS en RIHS researchers Willeke Daamen, Frank Vandenbussche, Joris van Drongelen, Toin van Kuppevelt and Janneke Grutters have been granted 1.3 million euro for the development and evaluation of a new technology to prevent premature rupture of fetal membranes (iPPROM).
Guiding the surgeon real-time tumor visualization during surgery26 February 2020
Incomplete excision of tumor tissue negatively affects the prognosis of the patient. RIHS researcher Mark Rijpkema and colleagues are working on the development of new dual-labeled tracers and currently are implementing this into the clinic.
Jurgen Fütterer appointed Professor of Image-Guided Oncological Interventions26 February 2020
RIHS researcher Fütterer is an interventional radiologist and an expert in the field of cancer imaging techniques, image-guided interventions and robotics. He is also Professor at the Robotics and Mechatronics Group at the University of Twente.
KNAW Early Career Award for Geert Litjens13 February 2020
Twelve young researchers received the Early Career Award from KNAW on 4 february. One of them is RIHS researcher Geert Litjens. The Award is aimed at researchers in the Netherlands at the start of their career who are capable of developing innovative and original research ideas.
SPL Medical starts clinical trial with contrast agent ferrotran11 February 2020
SPL Medical is starting an international registration study for its contrast agent Ferrotran. The study is being conducted in ten hospitals in Germany, Switzerland and the Netherlands. RIHS researcher Jelle Barentsz discovered the value of this drug in patients with lymph node metastases.
New Guidelines for the detection of prostate cancer MRI instead of tissue samples3 February 2020
The module on diagnostic prostate MRI for the NVU guidelines for prostate carcinoma took effect on 29 January 2020. The development of these guidelines is due in part to the efforts of RIHS researcher Jelle Barentsz and Ivo Schoots (Erasmus MC).
RIMLS PhD retreat registration is open23 January 2020
Yearly, RIMLS PhD candidates gather for the two-day PhD Retreat. Apart from the science, this event is highly valued for the opportunity to meet and get to know fellow PhD candidates during the social activities. Early bird registration and abstract submission deadline: 4 March 2020.
Prostate cancer can now be diagnosed better using artificial intelligence9 January 2020
RIHS researchers Wouter Bulten and Geert Litjens have developed a ‘deep learning’ system that is better than most pathologists at determining the aggressiveness of prostate cancer. The Artificial Intelligence system taught itself to identify prostate cancer based on data from over 1200 patients.
Exploration meeting Academic Alliance on Oncology2 December 2019
Within the Academic Alliance, the Maastricht UMC+ and Radboudumc are already working together in several areas. And this is happening in more and more fields. On 27 November researchers from both umc's met during the fourth Exploration meeting, this time with the theme: Oncology.
KWF Roadshow 11 November 201910 October 2019
In which way(s) can KWF provide optimal support to oncological research and care? How can we maximize impact on our investments? These questions are pivotal in Ambition 2030: the vision that KWF developed in close cooperation with stakeholders in the oncological field.
RIMLS 25 years jubilee festival The Future is Yesterday3 October 2019
Together with more than 250 colleagues and alumni we celebrated 25 years of research into the molecular mechanisms of disease. During this exciting and informal event, we not only took a trip down memory lane, but also looked ahead to the next 25 years and beyond…...
Cost-effectiveness of mpMRI in active surveillance of prostate cancer25 June 2019
In European Urology Oncology Sejal Patel and colleagues evaluated the potential cost-effectiveness of including mpMRI in active surveillance for men diagnosed with low-risk prostate cancer in comparison to the standard monitoring program.
Intake of a reduced dose of pazopanib with food the effect on pharmacokinetics, patient safety and preference13 June 2019
In Clinical Pharmacology & Therapeutics Floor Lubberman and colleagues showed that the intake of 600mg pazopanib with food resulted in a bioequivalent exposure and was preferred over a standard pazopanib dose without food.
How do we keep new technology affordable to improve the lives of people?16 May 2019
Improving healthcare by means of new technological developments? We need to change the entire approach for evaluating the true impact , says Maroeska Rovers. By bringing together all stakeholders from the beginning, millions of euros can be saved.
Algorithm calculates the presence and aggressiveness of prostate tumors14 May 2019
A computer program that analyzes MRI images can reliably map the presence and even the aggressiveness of a prostate tumor. This is what Radboudumc researchers and international colleagues have published in the scientific journal Investigative Radiology.
A new therapeutic option for the treatment of castration-resistant prostate cancer5 February 2019
Jack Schalken and Vicky Luna Velez and colleagues, theme Urological cancers, published in Oncogene about suppression of prostate tumor cell survival by antisense oligonucleotide-mediated inhibition of AR-V7 mRNA synthesis.
Julia van Tol-Geerdink appointed member Dutch Health Council31 January 2019
Julia van Tol-Geerdink is appointed as member of the Dutch Health Council (Gezondheidsraad). She is now member of the permanent committee on Population screening and of the temporary committee on AAA screening (Abdominal Aorta Aneurysm).
MRI improves detection of prostate cancer Prostate biopsy no longer necessary for 50% of male patients4 December 2018
There is good news for the more than 40,000 men per year who go to the hospital for diagnosis because of elevated Prostate-Specific Antigen (PSA) levels. “Thanks to the use of MRI, we can reduce the number of prostate biopsies by half,” says Jelle Barentsz.
Active surveillance in the majority of Dutch patients with very low risk prostate cancer27 November 2018
In Prostate Cancer and Prostatic Diseases Katja Aben and colleagues showed that most Dutch patients with very low risk prostate cancer are managed with active surveillance, thereby delaying and possible avoiding therapy and its side effects.
Report of the 12th New Frontiers symposium Big data, better healthcare? - 1 November 20187 November 2018
Examples from the application of deep learning to image reading in pathology and radiology and the application of network medicine to monitor infectious disease outbreaks or collective mood states using twitter data showed the huge potential of big data approaches for building better healthcare.
Report of the 12th New Frontiers symposium Better care, network care? - 2 November 20187 November 2018
No easy answers at this symposium last Friday, only challenges that can be overcome if we succeed in 5 things. First and most radically, put patients in the center of healthcare. Second, start with assessing what the local population needs and not what local professionals have to offer.