News

Reduction in cerebral blood flow related to decline in brain function in people with Alzheimer's disease Brain areas involved in memory and task performance show the largest decline in perfusion

Young Investigator Award for Esmée Bakker

Esmée Bakker received the Young Investigator Award for her abstract ‘Acute and long-term mortality rates among participants of mass-participation sports events versus the general population.’

Want to be sustainable and cool? Choose fans more and aircon less Keep cool and help the environment

A recent published study led by the University of Sydney, has found using indoor fans more often allows people to reduce their air conditioner use without changing how hot they feel, paving a way for reducing future energy use and greenhouse gas emissions. Coen Bongers, is one of the co-authors.

Esmée Bakker obtained a Marie Skłodowska-Curie grant

Esmée Bakker obtained a Marie Skłodowska-Curie European Postdoctoral Fellowships (160k) of the Horizon 2020 of the European Union.

Veni for 8 researchers Radboudumc and Radboud University

NWO has awarded 89 promising young scientists Veni funding of up to 280,000 euros. Eight of them are from Radboudumc and Radboud University. They can develop their own research ideas over a period of three years.

Veni grants for RIMLS researchers

NWO has awarded 89 promising young scientists Veni funding of up to 280,000 euros. Three of them are from Radboud Institute of Molecular Life Sciences (RIMLS). They can develop their own research ideas over a period of three years.

Exercise program appears to be a good alternative to surgery for chronic chest pain Reduced risk of other conditions, hospitalizations, and mortality

Patients with chronic chest pain may benefit more from following an exercise program than from surgery in which doctors place a stent. Data from over 18,000 patients show a reduced risk of mortality, hospitalizations and other conditions.

How much should we exercise to live healthier lives? Research into the relationship between exercise, heart disease and mortality

It has long been known that exercise reduces the risk of many chronic diseases. However, we do not yet know exactly how much exercise is necessary to achieve health benefits.

Thomas van den Heuvel wins Stairway to Impact Award for safer pregnancies using AI Award for safer pregnancies using AI

Radboudumc researcher Thomas van den Heuvel receives the Stairway to Impact Award from Dutch Research Council NWO. He receives this prize for the development of the BabyChecker, a smartphone application that allows midwives to make ultrasounds during pregnancies.

Technology saves lives! 1.9 million euros from the Heart Foundation for developing smart watches

Niels van Royen is proud to be part of this consortium, initiated by Judith Bonnes, to develop a wrist band for early detection of cardiac arrest. Together with Erasmus, Reinier de Graaf and Corsano Health.

Dick Thijssen appointed Professor of Cardiovascular Physiology

Tiny blood vessels, big problems Radboudumc receives grant for international collaboration

The Radboudumc, together with the University of Cambridge, receives a grant of €1.8M from three collaborating cardiac foundations for international research into the small blood vessels in the brain. This study will be led by Neurologist Frank-Erik de Leeuw and internist Niels Riksen.

RIMLS awards call for nominations

RIMLS awards several prizes to stimulate and honor our (young) researchers. Upcoming awards are Supervisor of the Year, Best Master Thesis, Best Publication, Best Image and more. Send your nominations now before 24 November 2021.

Turbo Grants for four medical-technical research projects

Four TURBO grants were recently awarded to new technical-medical research proposals. The grants are part of the TURBO program, a collaboration between the University of Twente (TechMed Centre) and the Radboudumc.

AI helps the defibrillator think

In the future, the AED and the defibrillator will be able to do more than they do today. Now the devices can only give patients who need to be resuscitated a shock, but in time it will be possible, with the help of artificial intelligence, to say more about the condition of the patient.

How are the Dutch Olympians prepared for the heat and humidity of Tokyo?

Personal heat preparedness advice for Dutch Olympic athletes

COVID-19 associated coagulopathy - lessons after 1 year

Jenneke Leentjens, Saskia Middeldorp, and colleagues, published a review on the current knowledge of COVID-19 associated coagulopathy and the role of antithrombotic therapies in the Lancet Haematology.

Experts call for urgent action to reduce global burden of cardiovascular disease in women by 2030

There is an urgent need to address this, states the international Lancet 'Women and Cardiovascular Disease' Commission

Royal decorations for Nicoline Hoogerbrugge, Jolanda de Vries, Koos van der Velden and Jan Buitelaar

Nicoline Hoogerbrugge, Jolanda de Vries, Koos van der Velden and Jan Buitelaar are appointed by His Majesty as Knight in the Order of the Dutch Lion, a highly prestigious decoration on 26 April 2021.

Patients who are obese or overweight are at risk for a more severe course of COVID-19

International study shows risk of mortality does not increase

Exercise prevents new cardiovascular diseases

Exercise lowers the risk of glucose intolerance, obesity, elevated cholesterol and hypertension. The risk of new cardiovascular diseases can be lowered by an individual exercise guideline, argues epidemiologist Esmée Bakker in her dissertation on March 4.

Arterial wall inflammation and increased hematopoietic activity in patients with primary aldosteronism

Niels Riksen and colleagues identified increased inflammatory activity in patients with primary aldosteronism.

Water as a new tool for cardiac screening for chest pain

Patients with chest pain not caused by a narrowing of the coronary arteries often do not know the cause of their symptoms. Scientists at the Radboudumc have successfully used a new technique to investigate other causes in the coronary arteries of the heart.

Reducing sitting time improves blood flow in the brain and in the legs

During a regular day, the average person sits for 8-10 hours. These high levels of sitting time seem linked to an increased risk for both cardiovascular and cerebrovascular diseases.

We are getting less physically active due to the coronavirus pandemic

“If exercise was available in the form of a pill, it would be the most commonly prescribed drug in the world.”

Pregnancy complications and early menopause affect cardiovascular disease in women

A number of specific conditions in women are important in their risk of cardiovascular disease. These include high blood pressure during pregnancy, gestational diabetes and early menopause.

RIMLS online award ceremony proudly presenting the winners

In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony. 

Reprogramming of bone marrow myeloid precursor cells in patients with severe coronary artery disease

Exploratory ''first-in-man'' study adds a new dimension to the role of our innate immune system in the development of cardiovascular disease. This study from Niels Riksen and colleagues is published in Elife.

Cum Laude PhD defense for Vincent Aengevaeren

We congratulate Vincent Aengevaeren! After defending his thesis entitled: ‘Potential Detrimental Effects of Exercise on the Heart’ on 28 October, Vincent attained his PhD degree with honors. Vincent had been appointed on a RIHS Junior Researcher grant.

Dora the explorer: exploring new ways of recognition and reward in science Blog by Siroon Bekkering

This blog by Siroon Bekkering, theme Vascular Damage, is a great way to draw more attention to the discussion around recognition and reward.

Centuries-old medicine reduces the risk of new cardiovascular disease in heart patients

Colchicine, an anti-inflammatory drug that has been used for gout for centuries, has been shown to prevent cardiovascular disease in patients who have had a heart attack or are suffering from narrowed coronary arteries. Results of the study are published in the New England Journal of Medicine.

Can a change in lifestyle relieve heart cramps?

Cardiac spasm, or angina pectoris, is a common heart condition. Even though these patients are well monitored and treated, they are still at risk of more severe heart failure.

Transfer of new anti-hepatitis C drugs across the human placenta

In a recent publication in American Journal of Obstetrics and Gynecology, researchers from the Departments of Pharmacology and Toxicology, Pharmacy, Obstetrics and Gynecology, Gastroenterology and Hepatology, investigated the placental passage of two such drugs for the first time.

Long-term and acute benefits of reduced sitting on vascular flow and function

In Medicine and Science in Sports and Exercise Yvonne Hartman described a 16-week reduced sitting intervention that improved vascular function and cerebral blood flow. This highlights the potential benefits of reducing sedentary behaviour to improve cardio- or cerebrovascular risk.

Cardiac rehabilitation has a positive impact on the life expectancy of cardiac patients

All cardiovascular patients can benefit from participation in a cardiac rehabilitation program. People who participate in a program, in which they gain more knowledge about risk factors for cardiovascular disease and receive advice about lifestyle and stress management, live longer on average.

Cardiac function in relation to myocardial injury in hospitalised patients with COVID-19

In Netherlands Heart Journal RIHS researcher Frederik van den Heuvel described that in hospitalized COVID-19 patients, COVID-19 predominantly affects the respiratory system, while cardiac dysfunction occurs less often.

Jan Hein Cornel and Robert-Jan van Geuns appointed as full Professors of Cardiology

On 1 April, two new professors were added to the Cardiology department. Jan Hein Cornel has been named by special appointment as professor of Inflammation in Atherosclerotic Cardiovascular Disease, and Robert-Jan van Geuns has been appointed as the new professor of Interventional Cardiology.

Cooling strategies for COVID-19 health personnel to attentuate PPE-induced heat strain

Radboudumc develops infographic with cooling information

Set7 regulates enhanced cytokine production in trained immunity in vitro

Postdoc Sam Keating and colleagues from the group of Niels Riksen, theme Vascular damage, revealed Set7 as a key regulator of trained immunity. They have published their findings in Cell Reports. 

Marc Spaanderman appointed Professor of Obstetrics

Marc Spaanderman has been appointed Professor of Obstetrics at Radboud University/ Radboud university medical center, with effect from 1 March 2020.

Catecholamines induce trained immunity in monocytes in vitro and in vivo

Niels Riksen and colleagues contributed data in Circulation Research, to the understanding of pathways driving inflammatory changes in conditions characterized by high catecholamine levels, and proposed that trained immunity underlies the increased cardiovascular event rate in PHEO patients.

RIMLS PhD retreat registration is open

Yearly, RIMLS PhD candidates gather for the two-day PhD Retreat. Apart from the science, this event is highly valued for the opportunity to meet and get to know fellow PhD candidates during the social activities. Early bird registration and abstract submission deadline: 4 March 2020.

Mohrmann Stipend for Bakker and Peters

Tuesday 10 December, Esmée Bakker and Yonne Peters were awarded a Christine Mohrmann stipend. The grant – 5000 euros each – gives them an opportunity to spend time at another university, preferably one abroad.

Dietrich-Knorr Prize for Hedi Claahsen-van der Grinten

Hedi Claahsen-van der Grinten, theme Vascular damage, received the Dietrich-Knorr prize 2019 for the best published paper in the field of adrenal research, for her publication in the Journal of Clinical Endocrinology & Metabolism.

Dutch National Postdoc award for Siroon Bekkering

Siroon Bekkering, theme Vascular damage, will use the prize money (€10,000) for her follow-up research into the memory of the innate immune system of patients with cardiovascular diseases.

Dekker personal grants call for proposals

These personal grants are intended for talented (clinical) investigators in the field of cardiovascular research. The deadline for submission is 4 February 2020.

Knowledge translation in health how implementation science could contribute more

In BMC Medicine Michel Wensing and Richard Grol reflect on the development of implementation science in health in the previous decade and give recommendations for how it could contribute more.

RIMLS awards call for nominations

RIMLS awards several prizes to stimulate and honor our (young) researchers. Please find here an overview of the upcoming awards. Deadline 12 December 2019.

3D breast ultrasound elastography to improve breast cancer detection

One out of seven women will be diagnosed with breast cancer during their life. Early detection of breast cancer is important to increase the survival rate. Gijs Hendriks graduated recently on a new technique, 3D elastography, to detect breast cancer better.

RIMLS 25 years jubilee festival The Future is Yesterday

Together with more than 250 colleagues and alumni we celebrated 25 years of research into the molecular mechanisms of disease. During this exciting and informal event, we not only took a trip down memory lane, but also looked ahead to the next 25 years and beyond…...