News Biobank

New Automated PBMC isolation method introduced in LMI.

The Radboud Biobank (RB) and the laboratory of Medical Immunology (LMI) are making plans to replace the density gradient centrifugation method with a new automated PBMC isolation method, the AutoMACS Pro Separator.

Health-RI, geared up to accelerate

The Dutch cabinet has selected Health-RI's National Growth Fund proposal for a national health data infrastructure. On 5 October, the kick-off will take place during a live meeting in Jaarbeurs Media Plaza in Utrecht.

SUNRISE-CRC sub-biobank

The main purpose of SUNRISE-CRC is to determine whether treatment with a high dose of sunitinib provides a better chance of survival and slows the progression of (colo)rectal cancer (CRC) more than standard treatment with TAS-102.

PRECISE sub-biobank

The aim of the PRECISE biobank is to develop the first, smart multi-modal liquid biopsy test service for the prediction of immune checkpoint inhibitor response in urothelial cancer (UC) patients – the PRECISE IVD.

Lysine Metabolism sub-biobank

Hereditary metabolic disorders form a large group of more than 1,400 rare disorders in which an error in the DNA causes abnormalities in the process in which proteins, fats and carbohydrates are converted into smaller building materials and energy.

Hyperintense sub-biobank

Cerebral small vessel disease (SVD), encompasses a collection of pathologies that affect the smallest blood vessels in the brain.

Duchenne Muscular Dystrophy Parel

Duchenne muscular dystrophy (DMD) is a rare X-linked hereditary disorder (locus Xp21.2) and therefore occurs almost exclusively in boys.

ADOPT sub-biobank

In the multicenter clinical study ADOPT, 280 men with oligo-recurrent prostate cancer from 10 participating hospitals in the Netherlands are randomized to receive standard metastasis-targeted radiotherapy or metastasis-targeted radiotherapy in combination with 6 months of ADT.

Myotonic Dystrophy sub-biobank

Myotonic Dystrophy is an autosomal dominantly inherited multisystem disorder (MD type 1 and MD type 2).

Radboud Biobank Oncology

The Radboud Biobank Oncology stores biomaterial (plasma, serum, cfDNA, tumor tissue) from patients with a proven malignancy or a high suspicion of malignancy, together with data about the patient's disease course.

Overview of samples in storage

It is possible to request an overview of the samples stored in a sub-biobank when desired.

Magazine celebrating 10 years BBMRI.nl

In the past 10 years, BBMRI.nl has made great progress in fulfilling its mission to maximize the use of biomaterial, images and clinical data for health research.

Growth Fund invests in Health-RI proposal for health data infrastructure

The Dutch Government has decided to honor Health-RI's proposal for a national health data infrastructure.

GENPAD sub-biobank

The GENPAD Biobank is part of the GENPAD study and contains biomaterial and clinical data from patients with peripheral arterial disease.

CORONIS sub-biobank

The CORONIS Biobank will focus on research into the pathophysiology of ischemic stroke after COVID-19 infection.

Framework for standards and assessment of accessing identifiable patient data for medical scientific research

A Framework for standards and assessment of accessing identifiable patient data for medical scientific research has been developed in the Radboudumc.

Animation Radboud Biobank for patients

The Radboud Biobank has had an animation made to inform Radboudumc visitors about the Radboud Biobank and its purpose.

HEALTH-RI Biobank Community

Biobanks are an indispensable part of the infrastructure for health research. That is why BBMRI.nl, Parelsnoer and Health-RI are joining forces.

RICH sub-biobank

Spontaneous intracerebral hematomas (ICH) are the most deadly form of stroke. The RICH biobank collects biomaterial (DNA, plasma, serum and PAXgene) from patients with spontaneous ICH.

SHM sub-biobank

Stichting HIV Monitoring’s (SHM) mission is to increase knowledge and understanding of all relevant aspects of HIV infection.

REGenG sub-biobank

The Radboud Expertise Center Sex & Gender (REG & G) is responsible for patient care, education, and research regarding gender incongruity / dysphoria.

Review of the Code of Conduct for Health Research

A public review of the full draft Code of Conduct is expected to occur in early 2021.

Assessment of research with material from an existing biobank.

If you want to perform research with material from a biobank and the initiation of this biobank has already been approved by the CMO Radboudumc, you only need to submit an application to the CMO Radboudumc for assessment in certain cases.

Sub-biobank MEMORY

The MEMORY biobank focuses on research into biomarkers for memory impairment and dementia and their validation in clinical cohorts.

RYR1 sub-biobank

The RYR1 biobank is part of a study of the neuromuscular and multisystem features of patients with malignant hyperthermia or rhabdomyolysis related to RYR1 (ryanodine receptor type 1) variants.

Sub-biobank CDG Congenital Disorders of Glycosylation

New colleague

My name is Robbert Croes and I started mid 2020 as a data-scientist at the Radboud Biobank.

ProBCI sub-biobank

There is a pressing need for predictive biomarkers to personalize bladder cancer treatment.

Financial regulation for sub-biobanks

Sub-biobanks are not required to pay up-front for the processing and storage of biomaterials. The effectiveness of this pre-financing agreement however is dependent on adherence to the demands regarding delivery and processing according to the Radboud Biobank standard operating procedures.

Biobanking: the power of collecting

Urine, cerebrospinal fluid, blood. Everything is stored in Dutch biobanks. Collecting this takes a lot of time and money. Is it worth that? What does it yield?

Costs for internal researchers in case of request for samples

As of January 1, 2020, internal researchers who request samples from the Radboud Biobank will only be charged for the number of samples received.

New sub-biobanks

The Radboud Biobank has added one new sub-biobank to the collection: HEMLYM.

Biobank OPMD

In oculopharyngeal muscular dystrophy (OPMD), muscle strength slowly decreases due to a breakdown of muscle cells. The Biobank OPMD contains clinical data and residual biomaterial.

Biobank BVO

The Biobank BVO contains left-over cytological material from the cervical screening program. The ambition of the BVO Biobank is to make this residual material available for scientific research.

Pilot Broad Consent at the Gate

In line with the NFU initiative “Broad Consent at the Gate” (Breed Consent aan de Poort), the Radboud Biobank is currently conducting a feasibility study examining consent procedures for the use of residual material for scientific research.

BBMRI-NL series on sustainable biobanking

BBMRI-NL has made a series on sustainable biobanking, combining current knowledge from literature, workshops, and focus groups.

COREON and the Dutch Code of Conduct on data protection in health research

COREON is currently revising the Dutch Code of Conduct for data protection in health research.

Biobank information for patients on the Radboudumc website

There is patient information available about biobanking in Dutch.

Information letter and consent form - new template available

The Radboud Biobank has drafted a template for the Information letter and consent form.

Nijmegen Bladder Cancer Study (NBCS)

The aim of NBCS is to investigate lifestyle factors and genetic factors in relation to the risk of bladder cancer, the course of the disease, and the effect of therapy.

FUTURE Biobank

The “Follow-Up of Transient ischemic attack and stroke patients and Unelucidated Risk factor Evaluation” (FUTURE) study is a prospective cohort study of prognosis of stroke in young adults.

Nijmegen Four Day March Cohort

Participants in the Nijmegen Four Days Marches are asked annually to complete an online questionnaire.

AortaBank

The ambition of AortaBank is to store biomaterial and associated clinical data of all patients who undergo operations on the Aorta(valve).

Visibility of the Radboud Biobank

It is essential to have a complete and up-to-date list of publications where the Radboud Biobank has provided source material and data.

PhD defense Martin Boeckhout “The Ethics and Governance of Health Research Infrastructure"

New biomedical innovations offer the promise of personalised medicine and health. Getting there requires huge amounts of sensitive personal health and care data.

Opt-out versus Opt-In Consent for Residual Samples

The Radboud Biobank will be conducting a 6-month feasibility study, as proposed by the Netherlands Federation of University Medical Centers (NFU), to evaluate the impact of migrating to a opt-in method, which requires explicit consent from the patient for use of the residual material.

Biobanking with invasive procedures - new Radboudumc policy

Recently, the CMO-light decided to allow invasive procedures for biobanking under strict conditions.

Healthy Brain Cohort

The goal of the Healthy Brain Cohort is to undertake an innovative approach to understand the human brain by examining the brain’s integration, individuality and dynamics.