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650,000 Euro funding for research into the phasing out of medication for leukaemia patients
30 July 2020With a 650,000 euro funding from ZonMw, researchers from the Haematology and Pharmacy departments can develop a medication phasing out strategy for patients with chronic myeloid leukaemia. This strategy will be tested in practice.
Dolutegravir versus efavirenz in women starting HIV therapy in late pregnancy (DolPHIN-2)
12 May 2020In Lancet HIV RIHS researchers Angela Colbers and David Burger showed in an open-label, randomized controlled trial, that, when initiated in the 3rd trimester of pregnancy, achievement of VL <50cp/mL at delivery was more likely with dolutegravir-based therapy than with efavirenz-based regimens.
The effect of pregnancy on the pharmacokinetics of dolutegravir in women living with HIV
17 March 2020In Clinical infectious diseases RIHS researchers Pauline Bollen, Jolien Freriksen, Angela Colbers and David Burger together with researchers of the PANNA network showed that dolutegravir use in pregnancy results in effective plasma concentrations.
Dosing anticancer drugs in patients with renal or hepatic impairment
11 April 2019Renal or hepatic impairment is a common comorbidity for patients with cancer either because of the disease itself, toxicity of previous anticancer treatments, or because of other factors affecting organ function, such as increased age.
Importance of prospective studies in pregnant and breastfeeding women living with HIV
14 March 2019In Clinical Infectious Diseases Angela Colbers, Stein Schalkwijk and David Burger give considerations on how to effectively evaluate aspects of clinical pharmacology required for safe and effective treatment to optimize pharmacotherapy during pregnancy and breastfeeding.
Pharmacy receives prestigious European prize for research in Africa
27 September 2018On 17 September, David Burger, professor of clinical pharmacy, together with colleagues from the United Kingdom, Uganda and Zimbabwe, received the "Outstanding Research Team" award from the European - Developing Countries Clinical Trial Partnership (EDCTP).
WHO Toolkit Pregnant and breastfeeding women
8 August 2018Stein Schalkwijk, Angela Colbers and David Burger (Pharmacy) developed the Toolkit in cooperation with Mark Mirochnick (Boston University) as a part of “Toolkit for research and development of paediatric antiretroviral drugs and formulations”.
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Pharmacokinetics of HIV medicines in pregnant women
28 June 2018In Clinical Pharmacokinetics David Burger, Ruben van der Galiën and colleagues discuss that although yearly over a million of women with HIV get pregnant, it is often still unknown whether treatment with HIV-integrase inhibitors results in adequate drug exposure.
