Molecular scissors play a role in kidney and lung leakage in COVID-19 patients18 June 2020
‘Molecular scissors', play a role in leakage of fluid from blood vessels to lungs and kidneys in COVID-19 patients. The scissors cut the protective sugar layer in the blood vessels. The more serious the disease, the more active the scissors, wrote Johan van der Vlag and colleagues in MedRxiv.
New insight into the effect of hydroxychloroquine undermines its use in corona11 June 2020
Researchers at Radboud university medical center have discovered an as yet unknown effect of hydroxychloroquine. Raphael Duivenvoorden was interviewed in the program Op1 at NPO1 to elaborate on the findings. It seems unlikely that chloroquine has beneficial effect in corona infections.
Johan van der Vlag appointed as professor of Immunology of Kidney Diseases and Transplantation23 April 2020
Johan van der Vlag is an expert in unravelling the molecular and immunological mechanisms underlying kidney disease and transplantation. His research stems from clinical questions and focuses on the development of new diagnostic/prognostic and therapeutic strategies.
Dutch Kidney Foundation PhD grant for Johan van der Vlag and Tom Nijenhuis14 February 2020
Johan van der Vlag and Tom Nijenhuis, theme Renal disorders, received this grant for their joint research project “Targeting a novel paracrine signaling pathway between glomerular endothelium and podocytes to treat glomerular injury”.
Kolff grants Dutch Kidney Foundation for Raphaël Duivenvoorden and Jitske Jansen17 December 2019
The Dutch Kidney Foundation supports talented postdocs and physician researchers through providing personal grants that support different phases of a research career. This year Raphaël Duivenvoorden and Jitske Jansen, theme Renal disorders, received a Kolff grant.
Scaling up nanotherapy7 October 2019
Scaling up and translating nanotherapy from pre-clinical work in small animal models to a clinical application is not trivial. Raphael Duivenvoorden, theme Renal disorders, and colleagues, published their results on translating a new nanoimmunotherapy in the journal Science Translational Medicine.
A personal touch of Johan van der Vlag13 June 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Johan van der Vlag.
Diversity in Neutrophils Extracellular Traps11 January 2019
Johan van der Vlag, theme Renal disorders, and colleagues, developed a novel method that allows the discrimination of NETs generated through NOX-dependent or NOX-independent pathways. Their findings were published in Annals of the Rheumatic Diseases.
Kidney filter injury further elucidated20 August 2018
Tom Nijenhuis, theme Renal disorders, and colleagues elucidated a novel mechanism that links activity of the calcium-conducting ion channel TRPC6 to structural injury of the kidney filter epithelial cell, via the calcium-dependent protease calpain-1.