prof. dr. Saskia Middeldorp

Over Saskia Middeldorp

Saskia Middeldorp is Professor of Medicine and Head of the Department of Internal Medicine of the Radboud University Medical Center in Nijmegen, The Netherlands. Prior to her transfer to Nijmegen in January 2021, she has been full professor of Medicine at Amsterdam University Medical Centers for over 10 years, leading the clinical thrombosis and hemostasis research lines of the Department of Vascular Medicine. Since January 2023, Saskia Middeldorp is one of the 4 Research Domain Leaders in the Radboudumc Research Institution for Medical Innovation. Since 2025, she is President of the Dutch Internal Medicine Society.

Her present research focuses on several aspects of hereditary and acquired thrombophilia, women’s issues in thrombosis and hemostasis, and the clinical evaluation of new anticoagulants and antidotes. She is principal investigator of practice-changing trials such as the investigator-initiated ALIFE, ALIFE2 and Highlow randomized controlled trials.

Saskia Middeldorp is elected council member of the International Society of Thrombosis and Haemostasis, president-elect of the Netherlands Society of Internal Medicine, past chair of the INVENT-VTE network, and was Associate Editor of the Journal of Thrombosis and Haemostasis and Editorial Board Member of Blood.

In December 2016, she held the Ham-Wasserman Lecture and received the accompanying award in recognition of pioneering work in inherited thrombophilia at the annual American Society of Hematology (ASH) meeting in San Diego. In O2021, she received the Heijmans van den Bergh penning, a once-per-five-year honorary distinction of the Netherlands Internal Medicine Society for her achievements in terms of science, education, governance and being a role model for young internists. In November 2025, she held the Sol Sherry Distinguished Award Lecture in Thrombosis at the American Heart Association in New Orleans.

She was chair of the Thrombophilia Chapter of ASH VTE Guidelines (2023). Saskia Middeldorp has co-authored the Pregnancy chapter of the ASH pregnancy guideline in 2018 as well as the 9th Edition Antithrombotic Guidelines of the American College of Chest Physicians (ACCP) in 2012.

Saskia has supervised and still supervises numerous PhD students and has co-authored over 450 peer-reviewed papers and several book chapters, and reviews manuscripts for international scientific journals.